Compile Data Set for Download or QSAR
maximum 50k data
Found 225 with Last Name = 'chambers' and Initial = 'cl'
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085666((2S,3S,4R,5R)-5-{6-(2,2-Diphenyl-ethylamino)-2-[2-...)
Affinity DataKi:  0.0300nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085674((2S,3S,4R,5R)-5-[2-(4-Amino-cyclohexylamino)-6-(2,...)
Affinity DataKi:  0.0500nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085671((2S,3S,4R,5R)-5-[6-(2,2-Diphenyl-ethylamino)-2-(2-...)
Affinity DataKi:  0.0800nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085668((2S,3S,4R,5R)-5-[6-Amino-2-((1R,2R)-2-hydroxy-cycl...)
Affinity DataKi:  0.100nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085662((2S,3S,4R,5R)-5-[6-(2,2-Diphenyl-ethylamino)-2-((1...)
Affinity DataKi:  0.160nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085661((2R,3R,4S,5R)-2-[6-Amino-2-((1R,2R)-2-hydroxy-cycl...)
Affinity DataKi:  0.800nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKi:  1nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
TargetAdenosine receptor A1(GUINEA PIG)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKi:  1nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085658((2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin...)
Affinity DataKi:  1nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085664((2R,3R,4S,5R)-2-[6-Amino-2-((1S,2S)-2-hydroxy-cycl...)
Affinity DataKi:  1.80nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085663((2R,3R,4S,5R)-2-[2-Chloro-6-((R)-(S)-2-hydroxy-cyc...)
Affinity DataKi:  2nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085670((2S,3S,4R,5R)-5-(6-Amino-2-cyclopentylamino-purin-...)
Affinity DataKi:  2.20nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085672((2R,3R,4S,5R)-2-(6-Amino-2-cyclopentylamino-purin-...)
Affinity DataKi:  5.10nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085665((2S,3S,4R,5R)-5-[2-Cyclopentylamino-6-(2,2-dipheny...)
Affinity DataKi:  6.20nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085667((2R,3S,4R,5R)-2-Hydroxymethyl-5-{6-[(naphthalen-1-...)
Affinity DataKi:  9.40nMAssay Description:Agonistic activity against Adenosine A2A receptor on rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085658((2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin...)
Affinity DataKi:  17nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085667((2R,3S,4R,5R)-2-Hydroxymethyl-5-{6-[(naphthalen-1-...)
Affinity DataKi:  24nMAssay Description:Agonistic activity against Adenosine A1 receptor on rat whole-brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085669((2R,3R,4S,5R)-2-{2-Cyclopentylamino-6-[(naphthalen...)
Affinity DataKi:  25nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085673((2R,3R,4S,5R)-2-[2-Cyclopentylamino-6-(2,2-dipheny...)
Affinity DataKi:  36nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085660((2R,3R,4S,5R)-2-{6-[2-(3-Chloro-phenyl)-ethylamino...)
Affinity DataKi:  39nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085670((2S,3S,4R,5R)-5-(6-Amino-2-cyclopentylamino-purin-...)
Affinity DataKi:  80nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085664((2R,3R,4S,5R)-2-[6-Amino-2-((1S,2S)-2-hydroxy-cycl...)
Affinity DataKi:  84nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085675((2S,3S,4R,5R)-5-[6-Amino-2-(1-ethyl-propylamino)-p...)
Affinity DataKi:  85nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085663((2R,3R,4S,5R)-2-[2-Chloro-6-((R)-(S)-2-hydroxy-cyc...)
Affinity DataKi:  171nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085668((2S,3S,4R,5R)-5-[6-Amino-2-((1R,2R)-2-hydroxy-cycl...)
Affinity DataKi:  260nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085671((2S,3S,4R,5R)-5-[6-(2,2-Diphenyl-ethylamino)-2-(2-...)
Affinity DataKi:  263nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085674((2S,3S,4R,5R)-5-[2-(4-Amino-cyclohexylamino)-6-(2,...)
Affinity DataKi:  369nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085662((2S,3S,4R,5R)-5-[6-(2,2-Diphenyl-ethylamino)-2-((1...)
Affinity DataKi:  390nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085672((2R,3R,4S,5R)-2-(6-Amino-2-cyclopentylamino-purin-...)
Affinity DataKi:  549nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085673((2R,3R,4S,5R)-2-[2-Cyclopentylamino-6-(2,2-dipheny...)
Affinity DataKi: >612nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085666((2S,3S,4R,5R)-5-{6-(2,2-Diphenyl-ethylamino)-2-[2-...)
Affinity DataKi:  672nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085660((2R,3R,4S,5R)-2-{6-[2-(3-Chloro-phenyl)-ethylamino...)
Affinity DataKi: >1.00E+3nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085661((2R,3R,4S,5R)-2-[6-Amino-2-((1R,2R)-2-hydroxy-cycl...)
Affinity DataKi:  1.47E+3nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085665((2S,3S,4R,5R)-5-[2-Cyclopentylamino-6-(2,2-dipheny...)
Affinity DataKi: >5.00E+3nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085659((2R,3R,4S,5R)-2-{2-Cyclohexylamino-6-[(naphthalen-...)
Affinity DataKi:  1.03E+4nMAssay Description:Agonistic activity against Adenosine A2A receptor on rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085659((2R,3R,4S,5R)-2-{2-Cyclohexylamino-6-[(naphthalen-...)
Affinity DataKi:  4.50E+4nMAssay Description:Agonistic activity against Adenosine A1 receptor on rat whole-brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040583((R)-4-(1,3-Dioxo-5-propoxy-1,3-dihydro-isoindol-2-...)
Affinity DataIC50:  2.10nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040607((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)
Affinity DataIC50:  3.80nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040600((R)-4-(1,3-Dioxo-5-phenyl-1,3-dihydro-isoindol-2-y...)
Affinity DataIC50:  4.5nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040585((R)-2-[(S)-3-Methyl-1-((S)-1-methylcarbamoyl-2-phe...)
Affinity DataIC50:  4.80nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040594((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)
Affinity DataIC50:  5nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040593((R)-4-(5,7-Dioxo-5,7-dihydro-[1,3]dioxolo[4,5-f]is...)
Affinity DataIC50:  5nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040610((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)
Affinity DataIC50:  6.70nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040597((R)-4-(4-Methoxy-1,3-dioxo-1,3-dihydro-benzo[f]iso...)
Affinity DataIC50:  7.40nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040596((R)-4-(1,3-Dioxo-1,3-dihydro-pyrrolo[3,4-b]quinoli...)
Affinity DataIC50:  7.5nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040616((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)
Affinity DataIC50:  11nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040593((R)-4-(5,7-Dioxo-5,7-dihydro-[1,3]dioxolo[4,5-f]is...)
Affinity DataIC50:  12nMAssay Description:Activity against human collagenase (MMP-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040592((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)
Affinity DataIC50:  12nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040609((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)
Affinity DataIC50:  13nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040613((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)
Affinity DataIC50:  14nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 225 total ) | Next | Last >>
Jump to: