Affinity DataKi: 250nMAssay Description:Inhibition of human norepinephrine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 1.35E+3nMAssay Description:Inhibition of human MMP12More data for this Ligand-Target Pair
Affinity DataKi: 7.73E+3nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP10More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP15More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP7More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP20More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP24More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP25More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP26More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human TACEMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP1More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP3More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP8More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP9More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP14More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP16More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Concentration of the compound required in vitro to inhibit Matrix metalloproteinase-13More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Concentration of the compound required in vitro to inhibit Matrix metalloproteinase-13More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
Affinity DataIC50: 0.511nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxC expressed in Escherichia coli using UDP-3-O-N-acetylglucosamine substrate measured after 30 mins by mass sp...More data for this Ligand-Target Pair
Affinity DataIC50: 0.530nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxC expressed in Escherichia coli using UDP-3-O-N-acetylglucosamine substrate measured after 30 mins by mass sp...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 0.657nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:In vitro inhibition of Matrix metalloprotease-13.More data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Affinity DataIC50: 0.912nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 0.938nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 9 (MMP-9).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxC expressed in Escherichia coli using UDP-3-O-N-acetylglucosamine substrate measured after 30 mins by mass sp...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Concentration of the compound required in vitro to inhibit Matrix metalloproteinase-13More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 9 (MMP-9).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 13 (MMP-13).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 13 (MMP-13).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 13 (MMP-13).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 13 (MMP-13).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 13 (MMP-13).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 13 (MMP-13).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 13 (MMP-13).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Concentration of the compound required in vitro to inhibit Matrix metalloproteinase-13More data for this Ligand-Target Pair