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Found 456 with Last Name = 'chorev' and Initial = 'm'
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50007965(CHEMBL312194 | Tyr(psi)CH2O-Gly-Gly-Phe-Leu-NH2 | ...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity of the compound to opioid receptor mu was determined in rat brain using [3H]-DAGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity of the compound to opioid receptor mu was determined in rat brain using [3H]-DAGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50007965(CHEMBL312194 | Tyr(psi)CH2O-Gly-Gly-Phe-Leu-NH2 | ...)
Affinity DataKi:  7.80nMAssay Description:Binding affinity of the compound to opioid receptor delta was determined in rat brain using [3H]-DSTBULET as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  629nMAssay Description:Binding affinity of the compound to opioid receptor delta was determined in rat brain using [3H]-DSTBULET as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50007966(CHEMBL420022 | Tyr-Gly(psi)CH2O-Gly-PheLeu-NH2)
Affinity DataKi:  1.38E+3nMAssay Description:Binding affinity of the compound to opioid receptor mu was determined in rat brain using [3H]-DAGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50007966(CHEMBL420022 | Tyr-Gly(psi)CH2O-Gly-PheLeu-NH2)
Affinity DataKi:  9.20E+3nMAssay Description:Binding affinity of the compound to opioid receptor delta was determined in rat brain using [3H]-DSTBULET as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10804((3R)-3-[methyl(prop-2-yn-1-yl)amino]-2,3-dihydro-1...)
Affinity DataIC50:  7nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10807(1-[methyl(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-ind...)
Affinity DataIC50:  8nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10742(1-amino-2,3-dihydro-1H-inden-4-yl N,N-dimethylcarb...)
Affinity DataIC50:  9nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10796(1-(dimethylamino)-2,3-dihydro-1H-inden-4-yl N,N-di...)
Affinity DataIC50:  13nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Teva Pharmaceutical Industries

LigandPNGBDBM10742(1-amino-2,3-dihydro-1H-inden-4-yl N,N-dimethylcarb...)
Affinity DataIC50:  14nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10803(3-[methyl(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-ind...)
Affinity DataIC50:  15nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Teva Pharmaceutical Industries

LigandPNGBDBM10784(1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl ...)
Affinity DataIC50:  19nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10804((3R)-3-[methyl(prop-2-yn-1-yl)amino]-2,3-dihydro-1...)
Affinity DataIC50:  20nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10743(1-amino-2,3-dihydro-1H-inden-4-yl N-ethyl-N-methyl...)
Affinity DataIC50:  26nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10794(1-[methyl(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-ind...)
Affinity DataIC50:  27nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10726(3-[1-(dimethylamino)ethyl]phenyl N,N-dimethylcarba...)
Affinity DataIC50:  30nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10803(3-[methyl(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-ind...)
Affinity DataIC50:  30nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10806(3-[methyl(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-ind...)
Affinity DataIC50:  50nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10783(1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl ...)
Affinity DataIC50:  53nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Teva Pharmaceutical Industries

LigandPNGBDBM10743(1-amino-2,3-dihydro-1H-inden-4-yl N-ethyl-N-methyl...)
Affinity DataIC50:  54nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10807(1-[methyl(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-ind...)
Affinity DataIC50:  70nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10806(3-[methyl(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-ind...)
Affinity DataIC50:  70nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10824(3-{2-[methyl(prop-2-yn-1-yl)amino]propyl}phenyl N-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10824(3-{2-[methyl(prop-2-yn-1-yl)amino]propyl}phenyl N-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10823(3-{2-[methyl(prop-2-yn-1-yl)amino]propyl}phenyl N,...)
Affinity DataIC50:  120nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10812(3-[2-(dimethylamino)ethyl]phenyl N,N-dimethylcarba...)
Affinity DataIC50:  160nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10820(3-[2-(prop-2-yn-1-ylamino)propyl]phenyl N-methyl-N...)
Affinity DataIC50:  170nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10832(3-[2-(but-3-yn-2-ylamino)ethyl]phenyl N,N-dimethyl...)
Affinity DataIC50:  170nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Teva Pharmaceutical Industries

LigandPNGBDBM10813(3-[2-(prop-2-yn-1-ylamino)ethyl]phenyl N,N-dimethy...)
Affinity DataIC50:  210nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10813(3-[2-(prop-2-yn-1-ylamino)ethyl]phenyl N,N-dimethy...)
Affinity DataIC50:  220nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10830(3-[(2R)-2-[methyl(prop-2-yn-1-yl)amino]propyl]phen...)
Affinity DataIC50:  220nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10821(3-[2-(prop-2-yn-1-ylamino)propyl]phenyl N-cyclohex...)
Affinity DataIC50:  230nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10797(3-(2-aminoethyl)phenyl N,N-dimethylcarbamate | Phe...)
Affinity DataIC50:  230nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10799((3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Teva Pharmaceutical Industries

LigandPNGBDBM10833(3-[2-(but-3-yn-2-ylamino)ethyl]phenyl N-ethyl-N-me...)
Affinity DataIC50:  240nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10829(3-(N-Methyl,Ncyclohexylcarbamyloxy)-N-methyl-N-pro...)
Affinity DataIC50:  240nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Teva Pharmaceutical Industries

LigandPNGBDBM10832(3-[2-(but-3-yn-2-ylamino)ethyl]phenyl N,N-dimethyl...)
Affinity DataIC50:  240nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10783(1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl ...)
Affinity DataIC50:  260nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10831(3-[(2S)-2-[methyl(prop-2-yn-1-yl)amino]propyl]phen...)
Affinity DataIC50:  280nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10810(3-[2-(methylamino)ethyl]phenyl N,N-dimethylcarbama...)
Affinity DataIC50:  280nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10815(3-[2-(prop-2-yn-1-ylamino)ethyl]phenyl N-methyl-N-...)
Affinity DataIC50:  290nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Teva Pharmaceutical Industries

LigandPNGBDBM10793(7-(prop-2-yn-1-ylamino)-5,6,7,8-tetrahydronaphthal...)
Affinity DataIC50:  290nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10732(3-amino-2,3-dihydro-1H-inden-5-yl N-(4-methoxyphen...)
Affinity DataIC50:  300nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10799((3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10816(3-{2-[methyl(prop-2-yn-1-yl)amino]ethyl}phenyl N,N...)
Affinity DataIC50:  300nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Teva Pharmaceutical Industries

LigandPNGBDBM10778(3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl ...)
Affinity DataIC50:  310nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10822(3-[2-(prop-2-yn-1-ylamino)propyl]phenyl N-butyl-N-...)
Affinity DataIC50:  400nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10739(3-amino-2,3-dihydro-1H-inden-4-yl N,N-dimethylcarb...)
Affinity DataIC50:  460nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10741(3-(methylamino)-2,3-dihydro-1H-inden-4-yl N,N-dime...)
Affinity DataIC50:  510nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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