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Found 121 with Last Name = 'connelly' and Initial = 'ma'
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50389319(CHEMBL2063924)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50128164(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-chlo...)
Affinity DataIC50:  3nMAssay Description:Inhibition of CETP (unknown origin)-mediated transfer of [3H]cholesteryl ester from HDL donar particles to LDL acceptor particlesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50128164(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-chlo...)
Affinity DataIC50:  3nMAssay Description:Inhibition of CETP (unknown origin)-mediated transfer of [3H]cholesteryl ester from HDL donar particles to LDL acceptor particles in presence of buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199225(US9216998, 8)
Affinity DataIC50:  4nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199225(US9216998, 8)
Affinity DataIC50:  4nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50380257(CHEMBL2017253)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50380246(CHEMBL2017214)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443627(CHEMBL3092450 | US9216998, 5)
Affinity DataIC50:  14nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50389323(CHEMBL2063925)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443627(CHEMBL3092450 | US9216998, 5)
Affinity DataIC50:  17nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199219(US9216998, 7 | US9216998, Reference Compound 2)
Affinity DataIC50:  17nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199219(US9216998, 7 | US9216998, Reference Compound 2)
Affinity DataIC50:  22nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50433473(CHEMBL2381070)
Affinity DataIC50:  23nMAssay Description:Time dependent inhibition of human EL (19 to 500) expressed in HEK293 cells using PED-A1 as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199219(US9216998, 7 | US9216998, Reference Compound 2)
Affinity DataIC50:  26nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50389321(CHEMBL2063927)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50389322(CHEMBL2063929)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443625(CHEMBL3092448 | US9216998, 25)
Affinity DataIC50:  31nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199205(US9216998, 9)
Affinity DataIC50:  36nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50276348((2R, aS)-3,4-dihydro-2-[3-(1,1,2,2-tetrafluoroetho...)
Affinity DataIC50:  39nMAssay Description:Inhibition of human plasma-derived CETP activity by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443625(CHEMBL3092448 | US9216998, 25)
Affinity DataIC50:  39nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50389311(CHEMBL2063916)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50389318(CHEMBL2063923)
Affinity DataIC50:  43nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199205(US9216998, 9)
Affinity DataIC50:  43nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50276347((+/-)-1,1,1-trifluoro-3-(2-(3-(1,1,2,2-tetrafluoro...)
Affinity DataIC50:  45nMAssay Description:Inhibition of CETP (unknown origin)-mediated transfer of [3H]cholesteryl ester from HDL donar particles to LDL acceptor particlesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199219(US9216998, 7 | US9216998, Reference Compound 2)
Affinity DataIC50:  48nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50:  48nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50389307(CHEMBL2063928)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199226(US9216998, 10)
Affinity DataIC50:  54nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50389309(CHEMBL2063914)
Affinity DataIC50:  58nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50128164(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-chlo...)
Affinity DataIC50:  59nMAssay Description:Inhibition of CETP (unknown origin)-mediated transfer of [3H]cholesteryl ester from HDL donar particles to LDL acceptor particles in presence of huma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50389312(CHEMBL2063917)
Affinity DataIC50:  66nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199207(US9216998, 19)
Affinity DataIC50:  68nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50389308(CHEMBL2063913)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199223(US9216998, 6)
Affinity DataIC50:  71nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199226(US9216998, 10)
Affinity DataIC50:  75nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199229(US9216998, 27)
Affinity DataIC50:  82nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199207(US9216998, 19)
Affinity DataIC50:  87nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199221(US9216998, 3)
Affinity DataIC50:  96nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199216(US9216998, 22)
Affinity DataIC50:  101nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199229(US9216998, 27)
Affinity DataIC50:  108nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50389310(CHEMBL2063915)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199221(US9216998, 3)
Affinity DataIC50:  115nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199209(US9216998, 13)
Affinity DataIC50:  124nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199208(US9216998, 12)
Affinity DataIC50:  131nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199208(US9216998, 12)
Affinity DataIC50:  135nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199223(US9216998, 6)
Affinity DataIC50:  136nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199216(US9216998, 22)
Affinity DataIC50:  142nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199222(US9216998, 4)
Affinity DataIC50:  143nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199209(US9216998, 13)
Affinity DataIC50:  150nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50389319(CHEMBL2063924)
Affinity DataIC50:  150nMAssay Description:Inhibition of KHKC in human HepG2 cells assessed as level of fructose-1-phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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