TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of CETP (unknown origin)-mediated transfer of [3H]cholesteryl ester from HDL donar particles to LDL acceptor particlesMore data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of CETP (unknown origin)-mediated transfer of [3H]cholesteryl ester from HDL donar particles to LDL acceptor particles in presence of buff...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Time dependent inhibition of human EL (19 to 500) expressed in HEK293 cells using PED-A1 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of human plasma-derived CETP activity by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of CETP (unknown origin)-mediated transfer of [3H]cholesteryl ester from HDL donar particles to LDL acceptor particlesMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of CETP (unknown origin)-mediated transfer of [3H]cholesteryl ester from HDL donar particles to LDL acceptor particles in presence of huma...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 75nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 82nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 87nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 96nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 101nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 108nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
Affinity DataIC50: 115nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 124nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 131nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 135nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 136nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 142nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 143nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of KHKC in human HepG2 cells assessed as level of fructose-1-phosphateMore data for this Ligand-Target Pair