Affinity DataKi: 0.0100nMAssay Description:Inhibition of DHFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibitory constant against thymidylate synthase from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibitory constant against thymidylate synthase from Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibitory constant against thymidylate synthase from Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibitory constant against thymidylate synthase from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibitory constant against thymidylate synthase from Lactobacillus caseiMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of thymidin synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibitory constant against thymidylate synthase from Escherichia coliMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Inhibitory constant against human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibitory constant against thymidylate synthase from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibitory constant against thymidylate synthase from Lactobacillus caseiMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Inhibitory constant against human thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 8.5nMAssay Description:Inhibitory constant against human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 9.40nMAssay Description:Inhibitory constant against thymidylate synthase from Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of Escherichia coli beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate after 180 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Inhibitory constant against human thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibitory constant against human thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of human thymidylate synthase expressed in Escherichia coli incubated for 1 hr by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibitory constant against thymidylate synthase from Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of Escherichia coli beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibition of Escherichia coli beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibition of Escherichia coli beta-lactamaseMore data for this Ligand-Target Pair
TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Homo sapiens (Human))
University Of Dundee
Curated by ChEMBL
University Of Dundee
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Competitive inhibition of human FolD dehydrogenase activityMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of Escherichia coli beta-lactamaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of Escherichia coli beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Inhibition of Escherichia coli beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Inhibition of Escherichia coli beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of Escherichia coli beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Inhibition of Escherichia coli beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
Affinity DataKi: 60nM ΔG°: -40.5kJ/molepH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
Affinity DataKi: 60nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate after 180 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 80nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
Affinity DataKi: 80nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Inhibition of Escherichia coli beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Apparent inhibition constant against Escherichia coli AmpC beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataKi: 82nMAssay Description:Inhibition of Escherichia coli beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataKi: 83nMAssay Description:Inhibition of Escherichia coli beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 100nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate after 180 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate after 180 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 120nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate after 180 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 170nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of Escherichia coli beta-lactamaseMore data for this Ligand-Target Pair