Compile Data Set for Download or QSAR
maximum 50k data
Found 27 with Last Name = 'curtis' and Initial = 'dr'
TargetGamma-aminobutyric acid receptor subunit gamma-1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021185(5-Aminomethyl-4,5-dihydro-isoxazol-3-ol | CHEMBL42...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of [3H]-GABA binding to Gamma-aminobutyric-acid receptor of rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit gamma-1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM23183(5-(aminomethyl)-1,2-oxazol-3-ol | Agarin | CHEMBL2...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibition of [3H]-GABA binding to Gamma-aminobutyric-acid receptor of rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit gamma-1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)
Affinity DataIC50:  33nMAssay Description:In vitro inhibition of [3H]-GABA binding to Gamma-aminobutyric-acid receptor of rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit gamma-1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021189(5-Aminomethyl-4,5-dihydro-isoxazol-3-ol | CHEMBL40...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibition of [3H]-GABA binding to Gamma-aminobutyric-acid receptor of rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit gamma-1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021186(4-Amino-3-hydroxy-butyric acid | CHEMBL296263 | S(...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibition of [3H]-GABA binding to Gamma-aminobutyric-acid receptor of rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro effect on GABA uptake in a crude preparation of synaptosomes from rat brain.More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50226144(2,4-Diamino-Butyric Acid | CHEBI:64307 | CHEMBL307...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibition of rat neuronal (synaptosomal) GABA uptake.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro inhibition of GABA uptake in rat brain synaptic membranesMore data for this Ligand-Target Pair
LigandPNGBDBM50021186(4-Amino-3-hydroxy-butyric acid | CHEMBL296263 | S(...)
Affinity DataIC50:  2.90E+4nMAssay Description:In vitro inhibition of GABA uptake in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021187(4-Amino-3-hydroxy-butyric acid | CHEMBL290216 | R(...)
Affinity DataIC50:  6.70E+4nMAssay Description:In vivo inhibition of GABA uptake in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021189(5-Aminomethyl-4,5-dihydro-isoxazol-3-ol | CHEMBL40...)
Affinity DataIC50:  7.00E+4nMAssay Description:In vivo inhibition of GABA uptake in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit gamma-1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021262(4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-5-ium-3-...)
Affinity DataIC50:  7.20E+4nMAssay Description:In vitro affinity for GABA binding sites on purified synaptic membranes from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50225363(CHEMBL40363)
Affinity DataIC50:  1.30E+5nMAssay Description:In vitro inhibition of GABA uptake in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50226141(CHEMBL309688)
Affinity DataIC50:  1.30E+5nMAssay Description:In vitro inhibition of rat neuronal (synaptosomal) GABA uptake.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50226145(CHEMBL150830)
Affinity DataIC50:  1.60E+5nMAssay Description:In vitro inhibition of rat neuronal (synaptosomal) GABA uptake.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021262(4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-5-ium-3-...)
Affinity DataIC50:  1.60E+5nMAssay Description:In vitro effect on GABA uptake in a crude preparation of synaptosomes from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224812(CHEBI:35010 | CHEMBL170539)
Affinity DataIC50:  2.20E+5nMAssay Description:In vitro effect on GABA uptake in a crude preparation of synaptosomes from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224810(CHEMBL171241)
Affinity DataIC50:  2.30E+5nMAssay Description:In vitro effect on GABA uptake in a crude preparation of synaptosomes from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50226143(CHEMBL305673)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibition of rat neuronal (synaptosomal) GABA uptake.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50226142(CHEMBL292757)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibition of rat neuronal (synaptosomal) GABA uptake.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50226146(CHEMBL74364)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibition of rat neuronal (synaptosomal) GABA uptake.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50224808(CHEMBL309689)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibition of rat neuronal (synaptosomal) GABA uptake.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM23183(5-(aminomethyl)-1,2-oxazol-3-ol | Agarin | CHEMBL2...)
Affinity DataIC50:  3.20E+5nMAssay Description:In vitro inhibition of GABA uptake in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224811(CHEMBL170753)
Affinity DataIC50:  4.00E+5nMAssay Description:In vitro effect on GABA uptake in a crude preparation of synaptosomes from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224809(CHEBI:34373 | Gaboxadol | LU-02030 | MK-0928)
Affinity DataIC50: >5.00E+5nMAssay Description:In vitro effect on GABA uptake in a crude preparation of synaptosomes from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021185(5-Aminomethyl-4,5-dihydro-isoxazol-3-ol | CHEMBL42...)
Affinity DataIC50: >5.00E+5nMAssay Description:In vitro inhibition of GABA uptake in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224808(CHEMBL309689)
Affinity DataIC50: >5.00E+5nMAssay Description:In vitro effect on GABA uptake in a crude preparation of synaptosomes from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed