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Found 216 with Last Name = 'duncan' and Initial = 'jn'
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50056445(1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroerg...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity towards Serotonin 5-hydroxytryptamine 1A receptor by displacement of [3H]-(+)-8-OH-DPAT.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
University Of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50016777(((R)-8-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  0.5nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50056445(1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroerg...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity towards Dopamine receptor D2 by displacement of [3H]-U-86,170.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
University Of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034366(CHEMBL28437 | Trifluoro-methanesulfonic acid 7-dip...)
Affinity DataKi:  0.800nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
University Of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50407735(CHEMBL2021539)
Affinity DataKi:  1.30nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50051562(1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-p...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity of [3H]-Spiperone towards Dopamine receptor D4 expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50056445(1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroerg...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity towards Dopamine receptor D3 by displacement of [3H]-(+)-7-OH-DPAT.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50051561(1-((S)-2-Isochroman-1-yl-ethyl)-4-(4-methoxy-pheny...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity of [3H]-Spiperone towards Dopamine receptor D4 expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50056446((R)-5-Propylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity towards Dopamine receptor D2 by displacement of [3H]-U-86,170.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
University Of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034368(CHEMBL28313 | Trifluoro-methanesulfonic acid 7-pro...)
Affinity DataKi:  2.80nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | CHEMBL81330 | PNU 96415E | PNU-9...)
Affinity DataKi:  3nMAssay Description:Binding affinity of [3H]-Spiperone towards Dopamine receptor D4 expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Medicinaregatan

Curated by ChEMBL
LigandPNGBDBM50034368(CHEMBL28313 | Trifluoro-methanesulfonic acid 7-pro...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor in homogenated rat brain tissue, using by [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50017543((6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,...)
Affinity DataKi:  4nMAssay Description:Binding affinity towards Serotonin 5-hydroxytryptamine 1A receptor by displacement of [3H]-(+)-8-OH-DPAT.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50017543((6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,...)
Affinity DataKi:  4nMAssay Description:Binding affinity towards Dopamine receptor D3 by displacement of [3H]-(+)-7-OH-DPAT.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50017543((6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,...)
Affinity DataKi:  4nMAssay Description:Binding affinity towards Dopamine receptor D2 by displacement of [3H]-U-86,170.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50107877((4-Methoxy-indan-2-yl)-dipropyl-amine | CHEMBL4219...)
Affinity DataKi:  4.20nMAssay Description:Affinity at D2 dopamine receptor on CHO cell membranes by [3H]-PNU-86170 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity of the compound was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone)More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Medicinaregatan

Curated by ChEMBL
LigandPNGBDBM50107877((4-Methoxy-indan-2-yl)-dipropyl-amine | CHEMBL4219...)
Affinity DataKi:  5.10nMAssay Description:Binding affinity of the compound towards 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50107867((R)-2-Dipropylamino-indan-4-ol | (S)-2-Dipropylami...)
Affinity DataKi:  5.20nMAssay Description:Affinity at D2 dopamine receptor on CHO cell membranes by [3H]-PNU-86170 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
University Of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50407735(CHEMBL2021539)
Affinity DataKi:  6.70nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1D receptor alpha by using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataKi:  7.20nMAssay Description:Binding affinity towards Dopamine receptor D2 by displacement of [3H]-U-86,170.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(4) dopamine receptor(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50051565(4-[4-((S)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]...)
Affinity DataKi:  7.20nMAssay Description:Binding affinity of [3H]-Spiperone towards Dopamine receptor D4 expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50407737(CHEMBL2021538)
Affinity DataKi:  8.70nMAssay Description:In vitro binding affinity towards Dopamine receptor D2 by using [3H]U-86170 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Medicinaregatan

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataKi:  8.70nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor in homogenated rat brain tissue, using by [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  9nMAssay Description:Binding affinity of [3H]-spiperone towards cloned mammalian Dopamine receptor D4 expressed in cultured cells or from rat whole brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50056443((R)-5-Methylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-...)
Affinity DataKi:  9nMAssay Description:Binding affinity towards Dopamine receptor D2 by displacement of [3H]-U-86,170.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Medicinaregatan

Curated by ChEMBL
LigandPNGBDBM50034366(CHEMBL28437 | Trifluoro-methanesulfonic acid 7-dip...)
Affinity DataKi:  9.60nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor in homogenated rat brain tissue, using by [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Medicinaregatan

Curated by ChEMBL
LigandPNGBDBM50016737((8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dip...)
Affinity DataKi:  10nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor in homogenated rat brain tissue, using by [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
University Of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50407737(CHEMBL2021538)
Affinity DataKi:  10nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  10nMAssay Description:Binding affinity towards Dopamine receptor D2 by displacement of [3H]-U-86,170.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)
Affinity DataKi:  11nMAssay Description:Binding affinity against dopamine receptor D2 in rat brain tissue using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50056444((R)-5-Dimethylamino-5,6-dihydro-1H,4H-imidazo[4,5,...)
Affinity DataKi:  12nMAssay Description:Binding affinity towards Dopamine receptor D2 by displacement of [3H]-U-86,170.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
University Of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034366(CHEMBL28437 | Trifluoro-methanesulfonic acid 7-dip...)
Affinity DataKi:  12nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1D receptor alpha by using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
University Of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50407734(CHEMBL2021524)
Affinity DataKi:  13nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50107870(2-Dipropylamino-indan-5-ol | CHEMBL16409)
Affinity DataKi:  14nMAssay Description:Affinity at rat D3 dopamine receptor on CHO cell membranes by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50107874((5,6-Dimethoxy-indan-2-yl)-propyl-(2-thiophen-3-yl...)
Affinity DataKi:  14nMAssay Description:Affinity at rat D3 dopamine receptor on CHO cell membranes by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
University Of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034368(CHEMBL28313 | Trifluoro-methanesulfonic acid 7-pro...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1D receptor alpha by using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50407737(CHEMBL2021538)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity towards Dopamine receptor D3 by using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  15nMAssay Description:Binding affinity of the compound was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]-U-86,170)More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)
Affinity DataKi:  19nMAssay Description:Binding affinity towards Dopamine receptor D3 by displacement of [3H]-(+)-7-OH-DPAT.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Medicinaregatan

Curated by ChEMBL
LigandPNGBDBM50107867((R)-2-Dipropylamino-indan-4-ol | (S)-2-Dipropylami...)
Affinity DataKi:  19.5nMAssay Description:Binding affinity of the compound towards 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50040245(8-Methyl-6-(4-methyl-piperazin-1-yl)-11H-benzo[e]p...)
Affinity DataKi:  21nMAssay Description:Binding affinity of [3H]-Spiperone towards Dopamine receptor D4 expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50107883(CHEMBL142535 | [2-(4-Bromo-phenyl)-ethyl]-(5,6-dim...)
Affinity DataKi:  22nMAssay Description:Affinity at rat D3 dopamine receptor on CHO cell membranes by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50107882((5,6-Dimethoxy-indan-2-yl)-(3-phenyl-propyl)-propy...)
Affinity DataKi:  23nMAssay Description:Affinity at rat D3 dopamine receptor on CHO cell membranes by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  24nMAssay Description:Binding affinity towards Serotonin 5-hydroxytryptamine 1A receptor by displacement of [3H]-(+)-8-OH-DPAT.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50026847(1-[2-(6,7-Dimethoxy-isochroman-1-yl)-ethyl]-4-(4-f...)
Affinity DataKi:  24nMAssay Description:Binding affinity of [3H]-Spiperone towards Dopamine receptor D4 expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50051564(1-((R)-2-Isochroman-1-yl-ethyl)-4-(4-methoxy-pheny...)
Affinity DataKi:  25nMAssay Description:Binding affinity of [3H]-Spiperone towards Dopamine receptor D4 expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50041959(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  26nMAssay Description:Binding affinity of the compound was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone)More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(1A) dopamine receptor(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50026847(1-[2-(6,7-Dimethoxy-isochroman-1-yl)-ethyl]-4-(4-f...)
Affinity DataKi:  26nMAssay Description:Binding affinity of [3H]-SCH-23,390 towards Dopamine receptor D1 in cloned mammalian receptor expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50107869((5,6-Dimethoxy-indan-2-yl)-phenethyl-propyl-amine ...)
Affinity DataKi:  27nMAssay Description:Affinity at D2 dopamine receptor on CHO cell membranes by [3H]-PNU-86170 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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