Affinity DataKi: 0.0300nMAssay Description:Displacement of [125I]tyr11-SRIF from human sst2 receptor after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [125I]tyr11-SRIF from human sst4 receptor after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.17E+3nMAssay Description:Displacement of [125I]tyr11-SRIF from human sst4 receptor after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.65E+3nMAssay Description:Binding affinity to sst4 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.02E+3nMAssay Description:Binding affinity to human sst4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.05E+3nMAssay Description:Displacement of [125I]-SRIF14 from human sst4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.66E+3nMAssay Description:Displacement of [125I]tyr11-SRIF from human sst2 receptor after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.52E+3nMAssay Description:Binding affinity to sst2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4.69E+3nMAssay Description:Binding affinity to human sst2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.85E+3nMAssay Description:Displacement of [125I]tyr11-SRIF from human sst2 receptor after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 7.09E+3nMAssay Description:Displacement of [125I]tyr11-SRIF from human sst4 receptor after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Rattus norvegicus)
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 761nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 813nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair