TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Anacor Pharmaceuticals
Curated by ChEMBL
Anacor Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Inhibition of human recombinant PDE7A1 expressed in baculovirus-infected insect Sf9 cells by modified two-step methodMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Anacor Pharmaceuticals
Curated by ChEMBL
Anacor Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant PDE7A1 expressed in baculovirus-infected insect Sf9 cells by modified two-step methodMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Anacor Pharmaceuticals
Curated by ChEMBL
Anacor Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human recombinant PDE1A3 expressed in baculovirus-infected insect Sf9 cells by modified two-step methodMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Anacor Pharmaceuticals
Curated by ChEMBL
Anacor Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE1A3 expressed in baculovirus-infected insect Sf9 cells by modified two-step methodMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 in pooled human liver microsomes using dextromethorphan as substrate preincubated for 30 mins in presence of NADPH followed by s...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens)
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C19 in pooled human liver microsomes using (S)-(+)-mephenytoin as substrate preincubated for 30 mins in presence of NADPH followed ...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 in pooled human liver microsomes using diclofenac as substrate preincubated for 30 mins in presence of NADPH followed by substra...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 in pooled human liver microsomes using midazolam or testosterone as substrate preincubated for 30 mins in presence of NADPH foll...More data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Drugs For Neglected Diseases Initiative (Dndi)
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2 in pooled human liver microsomes using phenacetin as substrate preincubated for 30 mins in presence of NADPH followed by substra...More data for this Ligand-Target Pair