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Found 322 with Last Name = 'gjerstad' and Initial = 'e'
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410903(CHEMBL207598)
Affinity DataKi:  0.5nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410898(CHEMBL205757)
Affinity DataKi:  0.510nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410901(CHEMBL206413)
Affinity DataKi:  0.650nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410899(CHEMBL383674)
Affinity DataKi:  0.720nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410904(CHEMBL377532)
Affinity DataKi:  0.720nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50180400(2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-6,2'-...)
Affinity DataKi:  1nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50181921(2-[5-(5-carbamimidoyl-1H-indol-2-yl)-6-hydroxy-3'-...)
Affinity DataKi:  1nMAssay Description:Binding affinity to factor7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50189939(5-(4-amino-1H-pyrrolo[3,2-c]pyridin-2-yl)-6-hydrox...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to f7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50181916(CHEMBL206168 | [5-(5-carbamimidoyl-1H-benzoimidazo...)
Affinity DataKi:  2nMAssay Description:Binding affinity to factor7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50069984((R)-1-((S)-2-((S)-2-(benzyloxycarbonyl)-4-methylpe...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50189938(2-{5-(4-amino-1H-pyrrolo[3,2-c]pyridin-2-yl)-3'-[3...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity to f7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14312(CHEMBL214368 | CRA23 | ethyl N-[(2S)-6-amino-1-(5-...)
Affinity DataKi:  3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186211(CHEMBL211482 | N-[3'-(5-carbamimidoyl-1H-indol-2-y...)
Affinity DataKi:  3nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM13778(2-[3-(5-carbamimidoyl-1H-indol-2-yl)-4-hydroxy-5-(...)
Affinity DataKi:  3nMAssay Description:Binding affinity to factor7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50069985((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...)
Affinity DataKi:  3.70nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM14898(2-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-5-(...)
Affinity DataKi:  4nMAssay Description:Binding affinity to factor7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50181919(2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5'-fl...)
Affinity DataKi:  4nMAssay Description:Binding affinity to factor7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14311(CRA22 | N-[(2S)-6-amino-1-(5-{[4-(2,3-dihydro-1H-i...)
Affinity DataKi:  4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186210(2-(2,2'-dihydroxy-5-methyl-5'-ureidomethyl-bipheny...)
Affinity DataKi:  4nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186216(2-(5-fluoro-2,2'-dihydroxy-5'-ureidomethyl-bipheny...)
Affinity DataKi:  5nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410906(CHEMBL207160)
Affinity DataKi:  5.70nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14316((2R)-N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-inden-2-ylca...)
Affinity DataKi:  6nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM14863(({3-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-2...)
Affinity DataKi:  13nMAssay Description:Binding affinity to f7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186214(CHEMBL380098 | hexanoic acid [3'-(5-carbamimidoyl-...)
Affinity DataKi:  13nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50181917(3-[5-(5-carbamimidoyl-1H-indol-2-yl)-6-hydroxy-3'-...)
Affinity DataKi:  13nMAssay Description:Binding affinity to factor7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186217(CHEMBL377990 | [5-(5-carbamimidoyl-1H-benzoimidazo...)
Affinity DataKi:  14nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14152(6-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-C...)
Affinity DataKi:  14nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14863(({3-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-2...)
Affinity DataKi:  14nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50189941(2-{5-(4-amino-1H-pyrrolo[3,2-c]pyridin-2-yl)-6-hyd...)
Affinity DataKi:  15nMAssay Description:Binding affinity to f7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM13776(2-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-4-h...)
Affinity DataKi:  15nMAssay Description:Binding affinity to factor7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14150(APC-11417 | CA-12 | CRA-11417 | {amino[6-fluoro-2-...)
Affinity DataKi:  16nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186212(CHEMBL214351 | N-[3'-(5-carbamimidoyl-1H-indol-2-y...)
Affinity DataKi:  16nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186215(CHEMBL214352 | morpholine-4-carboxylic acid [3'-(5...)
Affinity DataKi:  17nMAssay Description:Binding affinity to f7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14481(CA-23 | [amino({5-[(3,4-dihydroxynaphthalene-2-)am...)
Affinity DataKi:  17nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50181915(2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-6-hyd...)
Affinity DataKi:  17nMAssay Description:Binding affinity to factor7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50189942(4-{3-[3'-(4-amino-1H-pyrrolo[3,2-c]pyridin-2-yl)-5...)
Affinity DataKi:  20nMAssay Description:Binding affinity to f7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14317(CRA28 | N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-inden-2-y...)
Affinity DataKi:  21nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50181920(2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-6-hyd...)
Affinity DataKi:  21nMAssay Description:Binding affinity to factor7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM14908(2-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-4-h...)
Affinity DataKi:  22nMAssay Description:Binding affinity to factor7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14307((2R)-N-[(1S)-1-{[6-amino-1-(1,3-benzothiazol-2-yl)...)
Affinity DataKi:  23nM ΔG°:  -43.2kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14314(CRA25 | prop-2-en-1-yl N-[(2S)-1-(5-{[4-(2,3-dihyd...)
Affinity DataKi:  25nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14350(2-{5-[amino(iminiumyl)methyl]-6-fluoro-1H-1,3-benz...)
Affinity DataKi:  30nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410900(CHEMBL207425)
Affinity DataKi:  32nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14142(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-phe...)
Affinity DataKi:  33nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50181918(3-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-6-hyd...)
Affinity DataKi:  36nMAssay Description:Binding affinity to factor7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410896(CHEMBL383122)
Affinity DataKi:  38nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14481(CA-23 | [amino({5-[(3,4-dihydroxynaphthalene-2-)am...)
Affinity DataKi:  41nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410907(CHEMBL437311)
Affinity DataKi:  45nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14316((2R)-N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-inden-2-ylca...)
Affinity DataKi:  53nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50189937((S)-N-[3'-(4-amino-1H-pyrrolo[3,2-c]pyridin-2-yl)-...)
Affinity DataKi:  81nMAssay Description:Binding affinity to f7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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