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Found 44 with Last Name = 'goekjian' and Initial = 'pg'
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Universite De Lyon

LigandPNGBDBM34110(glucopyranosylidene-spiro-isoxazoline, 4e)
Affinity DataKi:  630nM ΔG°:  -36.0kJ/molepH: 6.8 T: 2°CAssay Description:Phosphorylase activity was measured in the direction of glycogen synthesis by the release of orthophosphate from Glc-1-P. The enzyme was assayed in g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Universite De Lyon

LigandPNGBDBM34106(glucopyranosylidene-spiro-isoxazoline, 4a)
Affinity DataKi:  6.60E+3nM ΔG°:  -30.1kJ/molepH: 6.8 T: 2°CAssay Description:Phosphorylase activity was measured in the direction of glycogen synthesis by the release of orthophosphate from Glc-1-P. The enzyme was assayed in g...More data for this Ligand-Target Pair
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Universite De Lyon

LigandPNGBDBM34107(glucopyranosylidene-spiro-isoxazoline, 4b)
Affinity DataKi:  7.90E+3nM ΔG°:  -29.6kJ/molepH: 6.8 T: 2°CAssay Description:Phosphorylase activity was measured in the direction of glycogen synthesis by the release of orthophosphate from Glc-1-P. The enzyme was assayed in g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Universite De Lyon

LigandPNGBDBM34108(glucopyranosylidene-spiro-isoxazoline, 4c)
Affinity DataKi:  1.96E+4nM ΔG°:  -27.3kJ/molepH: 6.8 T: 2°CAssay Description:Phosphorylase activity was measured in the direction of glycogen synthesis by the release of orthophosphate from Glc-1-P. The enzyme was assayed in g...More data for this Ligand-Target Pair
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Universite De Lyon

LigandPNGBDBM34109(glucopyranosylidene-spiro-isoxazoline, 4d)
Affinity DataKi:  9.25E+4nM ΔG°:  -23.4kJ/molepH: 6.8 T: 2°CAssay Description:Phosphorylase activity was measured in the direction of glycogen synthesis by the release of orthophosphate from Glc-1-P. The enzyme was assayed in g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50:  51nMAssay Description:Inhibition of NPM/ALK (unknown origin) transfected in mouse BAF3 cells assessed as cell growth inhibition after 72 hrs by [3H]-thymidine incorporatio...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM482158(BDBM50242742 | TAE684)
Affinity DataIC50:  56nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448037(CHEMBL3115500)
Affinity DataIC50:  340nMAssay Description:Inhibition of NPM/ALK (unknown origin) transfected in mouse BAF3 cells assessed as cell growth inhibition after 72 hrs by [3H]-thymidine incorporatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM153477(US8999955, 5-hydroxy-1-trimethylsilanyl-3,3a,4,5-t...)
Affinity DataIC50:  620nMAssay Description:The tests are carried out as follows: the enzyme to be assayed was purified, for example by affinity chromatography on agarose beads. The catalytic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM153477(US8999955, 5-hydroxy-1-trimethylsilanyl-3,3a,4,5-t...)
Affinity DataIC50:  650nMAssay Description:The tests are carried out as follows: the enzyme to be assayed was purified, for example by affinity chromatography on agarose beads. The catalytic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448048(CHEMBL3115504)
Affinity DataIC50:  650nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448048(CHEMBL3115504)
Affinity DataIC50:  840nMAssay Description:Inhibition of NPM/ALK (unknown origin) transfected in mouse BAF3 cells assessed as cell growth inhibition after 72 hrs by [3H]-thymidine incorporatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448035(CHEMBL3115499)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of NPM/ALK (unknown origin) transfected in mouse BAF3 cells assessed as cell growth inhibition after 72 hrs by [3H]-thymidine incorporatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM153482(US8999955, 5-hydroxy-9-methoxy-1-trimethylsilanyl-...)
Affinity DataIC50:  1.60E+3nMAssay Description:The tests are carried out as follows: the enzyme to be assayed was purified, for example by affinity chromatography on agarose beads. The catalytic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM153483(US8999955, 5-hydroxy-8,9-methoxy-1-trimethylsilany...)
Affinity DataIC50:  1.70E+3nMAssay Description:The tests are carried out as follows: the enzyme to be assayed was purified, for example by affinity chromatography on agarose beads. The catalytic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM153481(US8999955, 5-hydroxy-8-methoxy-1-trimethylsilanyl-...)
Affinity DataIC50:  1.70E+3nMAssay Description:The tests are carried out as follows: the enzyme to be assayed was purified, for example by affinity chromatography on agarose beads. The catalytic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM153477(US8999955, 5-hydroxy-1-trimethylsilanyl-3,3a,4,5-t...)
Affinity DataIC50:  1.95E+3nMAssay Description:The tests are carried out as follows: the enzyme to be assayed was purified, for example by affinity chromatography on agarose beads. The catalytic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM153477(US8999955, 5-hydroxy-1-trimethylsilanyl-3,3a,4,5-t...)
Affinity DataIC50:  3.00E+3nMAssay Description:The tests are carried out as follows: the enzyme to be assayed was purified, for example by affinity chromatography on agarose beads. The catalytic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM153483(US8999955, 5-hydroxy-8,9-methoxy-1-trimethylsilany...)
Affinity DataIC50:  3.30E+3nMAssay Description:The tests are carried out as follows: the enzyme to be assayed was purified, for example by affinity chromatography on agarose beads. The catalytic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448047(CHEMBL3115503)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM153480(US8999955, 5-chloro-1-trimethylsilanyl-3,3a,4,5-te...)
Affinity DataIC50:  3.60E+3nMAssay Description:The tests are carried out as follows: the enzyme to be assayed was purified, for example by affinity chromatography on agarose beads. The catalytic a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM153481(US8999955, 5-hydroxy-8-methoxy-1-trimethylsilanyl-...)
Affinity DataIC50:  4.00E+3nMAssay Description:The tests are carried out as follows: the enzyme to be assayed was purified, for example by affinity chromatography on agarose beads. The catalytic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM153482(US8999955, 5-hydroxy-9-methoxy-1-trimethylsilanyl-...)
Affinity DataIC50:  4.80E+3nMAssay Description:The tests are carried out as follows: the enzyme to be assayed was purified, for example by affinity chromatography on agarose beads. The catalytic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448040(CHEMBL3115496)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of NPM/ALK (unknown origin) transfected in mouse BAF3 cells assessed as cell growth inhibition after 72 hrs by [3H]-thymidine incorporatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM153477(US8999955, 5-hydroxy-1-trimethylsilanyl-3,3a,4,5-t...)
Affinity DataIC50:  7.80E+3nMAssay Description:The tests are carried out as follows: the enzyme to be assayed was purified, for example by affinity chromatography on agarose beads. The catalytic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448044(CHEMBL3115497)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448046(CHEMBL3115493)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448045(CHEMBL3115502)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448044(CHEMBL3115497)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of NPM/ALK (unknown origin) transfected in mouse BAF3 cells assessed as cell growth inhibition after 72 hrs by [3H]-thymidine incorporatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448043(CHEMBL3115501)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM153477(US8999955, 5-hydroxy-1-trimethylsilanyl-3,3a,4,5-t...)
Affinity DataIC50:  2.60E+4nMAssay Description:The tests are carried out as follows: the enzyme to be assayed was purified, for example by affinity chromatography on agarose beads. The catalytic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448035(CHEMBL3115499)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448036(CHEMBL3115495)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448042(CHEMBL3115494)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448041(CHEMBL3115492)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM153480(US8999955, 5-chloro-1-trimethylsilanyl-3,3a,4,5-te...)
Affinity DataIC50:  6.30E+4nMAssay Description:The tests are carried out as follows: the enzyme to be assayed was purified, for example by affinity chromatography on agarose beads. The catalytic a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448040(CHEMBL3115496)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448037(CHEMBL3115500)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448038(CHEMBL3115498)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448039(CHEMBL3115491)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataEC50:  2.04E+3nMAssay Description:Competitive inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataEC50:  2.28E+4nMAssay Description:Competitive inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataEC50:  575nMAssay Description:Competitive inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using...More data for this Ligand-Target Pair