Affinity DataKi: 0.0130nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Displacement of [3H]citalopram from SERTMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:In vitro competitive binding versus [3H]-citalopram in murine kidney cells transfected with cDNA for human serotonin transporter (SERT)More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Binding affinity to human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Invitro competitive binding versus [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]citalopram from human SERTMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]citalopram from human SERTMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]PK11195 from PBR in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Competitive binding versus [N-methyl-3H]-WIN 35,428 in murine kidney cells transfected with human dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [125I]RTI55 from human DATMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:In vitro competitive binding versus [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)More data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:In vitro affinity determined using [3H]-WIN- 35428 in murine kidney cells transfected with human dopamine transporter (DAT)More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 0.490nMAssay Description:Invitro competitive binding versus [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)More data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of [125I]RTI55 from human DATMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [125I]RTI55 from human DATMore data for this Ligand-Target Pair
Affinity DataKi: 0.670nMAssay Description:In vitro competitive binding versus [3H]-citalopram in murine kidney cells transfected with cDNA for human serotonin transporter (SERT)More data for this Ligand-Target Pair
Affinity DataKi: 0.670nMAssay Description:In vitro affinity determined using [3H]-citalopram in murine kidney cells transfected with human serotonin transporter (SERT)More data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:In vitro binding affinity against human dopamine transporter in dog kidney cell line by using [125I]-RTI-55 as radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Tennessee At Knoxville
Curated by ChEMBL
University Of Tennessee At Knoxville
Curated by ChEMBL
Affinity DataKi: 0.690nMAssay Description:Inhibitory constant towards reuptake of [125I]-12 from dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 0.760nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of [125I]-Tyr0-sauvagine from human CRF1 receptor expressed in HEK293T cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of [125I]-Tyr0-sauvagine from CRF1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.820nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.840nMAssay Description:Displacement of [3H]nisoxetine from NET in rat brain membranesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Tennessee At Knoxville
Curated by ChEMBL
University Of Tennessee At Knoxville
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Inhibitory constant towards reuptake of [125I]-12 from dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition constant against [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with human dopamine transporter.More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 0.950nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 0.950nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair