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Found 2273 with Last Name = 'harriman' and Initial = 'gc'
TargetAdenosine deaminase(Bos taurus (bovine))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM22925((8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxol...)
Affinity DataKi:  0.00250nMAssay Description:Binding affinity (Ki) at calf intestinal adenosine deaminase.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463752(US10781204, Compound I-229 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463689(US10781204, Compound I-166 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463711(US10781204, Compound I-188 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463710(US10781204, Compound I-187 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463696(US10781204, Compound I-173 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463582(US10781204, Compound I-186 | US10781204, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463591(US10781204, Compound I-111 | US10781204, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463596(US10781204, Compound I-194 | US10781204, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463605(US10781204, Compound I-84 | US11434240, Compound I...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463609(US10781204, Compound I-88 | US11434240, Compound I...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463621(US10781204, Compound I-100 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463639(US10781204, Compound I-118 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463640(US10781204, Compound I-119 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463657(US10781204, Compound I-136 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463662(US10781204, Compound I-141 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463600(US10781204, Compound I-142 | US10781204, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463671(US10781204, Compound I-149 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463672(US10781204, Compound I-150 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463682(US10781204, Compound I-160 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463684(US10781204, Compound I-162 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463689(US10781204, Compound I-166 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463696(US10781204, Compound I-173 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463710(US10781204, Compound I-187 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463711(US10781204, Compound I-188 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463736(US10781204, Compound I-213 | US10781204, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463752(US10781204, Compound I-229 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM570426(US11434240, Compound I-62)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463591(US10781204, Compound I-111 | US10781204, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463596(US10781204, Compound I-194 | US10781204, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463605(US10781204, Compound I-84 | US11434240, Compound I...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463609(US10781204, Compound I-88 | US11434240, Compound I...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463621(US10781204, Compound I-100 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463639(US10781204, Compound I-118 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463640(US10781204, Compound I-119 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463657(US10781204, Compound I-136 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463662(US10781204, Compound I-141 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463600(US10781204, Compound I-142 | US10781204, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463671(US10781204, Compound I-149 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463672(US10781204, Compound I-150 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463682(US10781204, Compound I-160 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463684(US10781204, Compound I-162 | US11434240, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463736(US10781204, Compound I-213 | US10781204, Compound ...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM332992(US10196390, Compound I-281)
Affinity DataKi:  0.0510nMAssay Description:Inhibition of TYK2 JH1 domain (unknown origin) measured in presence of 10 uM ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM332893(US10196390, Compound I-182)
Affinity DataKi:  0.0810nMAssay Description:Inhibition of TYK2 JH1 domain (unknown origin) measured in presence of 10 uM ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM332847(US10196390, Compound I-136)
Affinity DataKi:  0.150nMAssay Description:Inhibition of TYK2 JH1 domain (unknown origin) measured in presence of 10 uM ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203905(4-(4-benzoylamino-naphthalene-1-sulfonylamino)-pip...)
Affinity DataKi:  0.170nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM50589369(CHEMBL5197513)
Affinity DataKi:  0.190nMAssay Description:Inhibition of TYK2 JH1 domain (unknown origin) measured in presence of 10 uM ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM332858(US10196390, Compound I-147)
Affinity DataKi:  0.210nMAssay Description:Inhibition of TYK2 JH1 domain (unknown origin) measured in presence of 10 uM ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM332993(US10196390, Compound I-282)
Affinity DataKi:  0.230nMAssay Description:Inhibition of TYK2 JH1 domain (unknown origin) measured in presence of 10 uM ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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