BindingDB PrimarySearch_ki

Found 1228 with Last Name = 'henke' and Initial = 'br'

Estrogen receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)

Ki: 0.220nMAssay Description:Ability to displace [3H]-17-beta-estradiol from Estrogen receptor alpha by scintillation proximity assay.More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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3D Structure (crystal)

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

PNG

BDBM50086433(CHEMBL3426034)

Ki: 0.300nMAssay Description:Inhibition of wild type fully glycosylated human recombinant CD38-catalyzed NAD hydrolysisMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Gastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by PDSP K_i Database

PNG

BDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)

Ki: 0.350nMMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

PNG

BDBM50086438(CHEMBL3426039)

Ki: 0.450nMAssay Description:Inhibition of wild type fully glycosylated human recombinant CD38-catalyzed NAD hydrolysisMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471981(CHEMBL446629)

Ki: 0.692nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

PNG

BDBM50086434(CHEMBL3426035)

Ki: 0.700nMAssay Description:Inhibition of wild type fully glycosylated human recombinant CD38-catalyzed NAD hydrolysisMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471983(CHEMBL149876)

Ki: 0.776nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471980(CHEMBL147095)

Ki: 0.851nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471978(CHEMBL147090)

Ki: 0.871nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471951(CHEMBL343210)

Ki: 0.891nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472023(CHEMBL148384)

Ki: 0.933nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472019(CHEMBL148668)

Ki: 0.977nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471959(CHEMBL146301)

Ki: 0.977nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50151001((S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-...)

Ki: 1nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL MMDB PC cid PC sid

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50085044((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-...)

Ki: 1.10nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50085044((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-...)

Ki: 1.10nMAssay Description:Binding affinity to human Peroxisome proliferator activated receptor gamma using scintillation proximity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50085044((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-...)

Ki: 1.10nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471953(CHEMBL356382)

Ki: 1.10nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50085044((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-...)

Ki: 1.10nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471968(CHEMBL358379)

Ki: 1.10nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471966(CHEMBL147935)

Ki: 1.30nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Gastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by PDSP K_i Database

PNG

BDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)

Ki: 1.32nMMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471974(CHEMBL148950)

Ki: 1.40nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472043(CHEMBL148596)

Ki: 1.5nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50418564(CHEMBL423026)

Ki: 1.5nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid Similars

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Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471982(CHEMBL147384)

Ki: 1.60nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472035(CHEMBL2112870)

Ki: 1.60nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472034(CHEMBL147021)

Ki: 1.70nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472037(CHEMBL414442)

Ki: 1.80nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471955(CHEMBL148797)

Ki: 1.80nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471970(CHEMBL148459)

Ki: 1.90nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471948(CHEMBL149647)

Ki: 2nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

PNG

BDBM50151001((S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-...)

Ki: 2nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL MMDB PC cid PC sid

Details Article PubMed

Estrogen receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)

Ki: 2.20nMAssay Description:Ability to displace [3H]-17-beta-estradiol from Estrogen receptor alpha by scintillation proximity assay.More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471954(CHEMBL358325)

Ki: 2.20nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472047(CHEMBL146355)

Ki: 2.20nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472024(CHEMBL145886)

Ki: 2.30nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472048(CHEMBL146562)

Ki: 2.30nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472041(CHEMBL147770)

Ki: 2.40nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471963(CHEMBL359285)

Ki: 2.60nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472021(CHEMBL146637)

Ki: 2.60nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472029(CHEMBL149780)

Ki: 2.60nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471991(CHEMBL146650)

Ki: 2.60nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50471989(CHEMBL149835)

Ki: 2.60nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472031(CHEMBL146579)

Ki: 2.70nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472028(CHEMBL150215)

Ki: 2.70nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472032(CHEMBL146584)

Ki: 2.80nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472025(CHEMBL150232)

Ki: 2.80nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50472011(CHEMBL148300)

Ki: 3nMAssay Description:Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50145710(2-Methyl-3-{4-[2-(5-methyl-2-thiophen-2-yl-oxazol-...)

Ki: 3nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

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Displayed 1 to 50 (of 1228 total ) | Next | Last >>

Filter my 1228 hits

Targets 19▿
- Peroxisome proliferator-activated receptor gamma 506
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 213
- Peroxisome proliferator-activated receptor alpha 136
- Estrogen receptor 87
- Estrogen receptor beta 81
- Gastrin/cholecystokinin type B receptor 73
- Cholecystokinin receptor type A 64
- Peroxisome proliferator-activated receptor delta 40
- Cytochrome P450 3A4 10
- Potassium voltage-gated channel subfamily H member 2 3
- Cytochrome P450 1A2 2
- Cytochrome P450 2C9 2
- Cytochrome P450 2C19 2
- Cytochrome P450 2D6 2
- Cytochrome P450 2C8 2
- Cytochrome P450 2B6 2
- Solute carrier family 22 member 6 1
- Solute carrier family 22 member 8 1
- Cytochrome P450 3A5 1
- ...
Publications 17▿
- J Med Chem 41: 5037-54 (1998) 181
- J Med Chem 58: 3548-71 (2015) 172
- J Med Chem 41: 5055-69 (1998) 138
- J Med Chem 45: 5492-505 (2002) 132
- J Med Chem 41: 5020-36 (1999) 94
- J Med Chem 43: 527-50 (2000) 72
- Bioorg Med Chem Lett 11: 2385-8 (2001) 70
- Bioorg Med Chem Lett 25: 1849-55 (2015) 52
- J Med Chem 40: 2706-25 (1997) 50
- Bioorg Med Chem Lett 11: 3111-3 (2001) 48
- Bioorg Med Chem 26: 2107-2150 (2018) 47
- J Med Chem 47: 4118-27 (2004) 47
- Bioorg Med Chem Lett 11: 1939-42 (2001) 36
- Bioorg Med Chem Lett 9: 3329-34 (2000) 32
- J Med Chem 64: 5037-5048 (2021) 22
- J Med Chem 39: 2655-8 (1996) 21
- J Med Chem 39: 3030-4 (1996) 14
Institutions 6▿
- Glaxo Wellcome Research And Development 566
- Glaxosmithkline 469
- Glaxo Wellcome Research & Development 72
- Mayo Clinic 52
- Glaxosmithkline Research And Development 47
- Hemoshear Therapeutics 22
Affinity: 0.0020 to 1.0E+7 nM▿
- Ki 445
- IC50 326
- EC50 457
- Affinity ≤ nM
Xtal structures: 16
Docked structures: 0
Catalog Cmpds: 24