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Found 2213 with Last Name = 'hol' and Initial = 'wg'
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045775((3R,4R)3-[1-(3-Cyclohexyl-3-hydroxy-propyl)-3,4-di...)
Affinity DataKi:  0.0430nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219919(6-(4-((phenethylamino)methyl)phenoxy)nicotinamide ...)
Affinity DataKi:  0.0700nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045775((3R,4R)3-[1-(3-Cyclohexyl-3-hydroxy-propyl)-3,4-di...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219921(4-(4-((phenethylamino)methyl)phenoxy)benzamide | C...)
Affinity DataKi:  0.150nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045775((3R,4R)3-[1-(3-Cyclohexyl-3-hydroxy-propyl)-3,4-di...)
Affinity DataKi:  0.150nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219919(6-(4-((phenethylamino)methyl)phenoxy)nicotinamide ...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219919(6-(4-((phenethylamino)methyl)phenoxy)nicotinamide ...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219921(4-(4-((phenethylamino)methyl)phenoxy)benzamide | C...)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045775((3R,4R)3-[1-(3-Cyclohexyl-3-hydroxy-propyl)-3,4-di...)
Affinity DataKi:  0.320nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219918(5-(4-((phenethylamino)methyl)phenoxy)picolinamide ...)
Affinity DataKi:  0.440nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  0.590nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50131892(CHEMBL421252 | N-(3-tert-Butyl-2,5-dioxo-1,4diaza-...)
Affinity DataKi:  0.670nMAssay Description:Binding affinity against Co(II)-substituted E. coli peptide deformylase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  0.870nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  0.870nMAssay Description:Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219921(4-(4-((phenethylamino)methyl)phenoxy)benzamide | C...)
Affinity DataKi:  0.920nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219919(6-(4-((phenethylamino)methyl)phenoxy)nicotinamide ...)
Affinity DataKi:  0.970nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219921(4-(4-((phenethylamino)methyl)phenoxy)benzamide | C...)
Affinity DataKi:  1.20nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219919(6-(4-((phenethylamino)methyl)phenoxy)nicotinamide ...)
Affinity DataKi:  1.20nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219919(6-(4-((phenethylamino)methyl)phenoxy)nicotinamide ...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]bremazocine from cloned human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045775((3R,4R)3-[1-(3-Cyclohexyl-3-hydroxy-propyl)-3,4-di...)
Affinity DataKi:  1.20nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219919(6-(4-((phenethylamino)methyl)phenoxy)nicotinamide ...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]bremazocine from human delta opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219918(5-(4-((phenethylamino)methyl)phenoxy)picolinamide ...)
Affinity DataKi:  1.80nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219921(4-(4-((phenethylamino)methyl)phenoxy)benzamide | C...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]bremazocine from human delta opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219925(6-(4-(2-(benzylamino)ethyl)phenoxy)nicotinamide | ...)
Affinity DataKi:  2.30nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219916(6-(4-((benzylamino)methyl)phenoxy)nicotinamide | C...)
Affinity DataKi:  2.5nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219918(5-(4-((phenethylamino)methyl)phenoxy)picolinamide ...)
Affinity DataKi:  2.90nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  3nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219916(6-(4-((benzylamino)methyl)phenoxy)nicotinamide | C...)
Affinity DataKi:  4.10nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045775((3R,4R)3-[1-(3-Cyclohexyl-3-hydroxy-propyl)-3,4-di...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]diprenorphine from cloned human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045775((3R,4R)3-[1-(3-Cyclohexyl-3-hydroxy-propyl)-3,4-di...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045775((3R,4R)3-[1-(3-Cyclohexyl-3-hydroxy-propyl)-3,4-di...)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]bremazocine from cloned human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045775((3R,4R)3-[1-(3-Cyclohexyl-3-hydroxy-propyl)-3,4-di...)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]bremazocine from human delta opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50226256(6-(4-(2-(3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phe...)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]diprenorphine from cloned human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219925(6-(4-(2-(benzylamino)ethyl)phenoxy)nicotinamide | ...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219925(6-(4-(2-(benzylamino)ethyl)phenoxy)nicotinamide | ...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50226245(6-(2-(4-methylpentyl)-2,3,4,5-tetrahydro-1H-benzo[...)
Affinity DataKi:  7.60nMAssay Description:Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219919(6-(4-((phenethylamino)methyl)phenoxy)nicotinamide ...)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219919(6-(4-((phenethylamino)methyl)phenoxy)nicotinamide ...)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]diprenorphine from cloned human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219918(5-(4-((phenethylamino)methyl)phenoxy)picolinamide ...)
Affinity DataKi:  8.5nMAssay Description:Displacement of [3H]bremazocine from human delta opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219918(5-(4-((phenethylamino)methyl)phenoxy)picolinamide ...)
Affinity DataKi:  9.60nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50226261(6-(2-phenethyl-2,3,4,5-tetrahydro-1H-benzo[c]azepi...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  11nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50226244(6-(2-isopentyl-2,3,4,5-tetrahydro-1H-benzo[c]azepi...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50226250(6-(2-pentyl-2,3,4,5-tetrahydro-1H-benzo[c]azepin-7...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50226249(6-(2-hexyl-2,3,4,5-tetrahydro-1H-benzo[c]azepin-7-...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50226252(6-(2-(5-methylhexyl)-2,3,4,5-tetrahydro-1H-benzo[c...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219921(4-(4-((phenethylamino)methyl)phenoxy)benzamide | C...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]bremazocine from human delta opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

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