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Found 286 with Last Name = 'huffman' and Initial = 'jw'
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50330773(((6aR,10aR)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a...)
Affinity DataKi:  0.0320nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50454329(CHEMBL2112647)
Affinity DataKi:  0.0320nMAssay Description:Ability to bind with Cannabinoid receptor 2 using [H]CP 55,940 as radioligand from cloned human receptor preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  0.280nMAssay Description:Binding affinity to human CB2 receptor by filtration assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  0.280nMAssay Description:Binding affinity to displace [3H]CP-55,940 from cloned human CB2 receptorMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50071414((6aR,10aR)-3-((1S,2R)-1,2-Dimethyl-heptyl)-6,6,9-t...)
Affinity DataKi:  0.460nMAssay Description:Binding affinity of the compound for the cannabinoid brain receptor (CB1) using [3H]- CP-55,940More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50071413((6aR,10aR)-3-((1S,2R)-1,2-Dimethyl-heptyl)-9-hydro...)
Affinity DataKi:  0.490nMAssay Description:Binding affinity of the compound for the cannabinoid brain receptor (CB1) using [3H]- CP-55,940More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50053357((6aR,10aR)-9-Hydroxymethyl-6,6-dimethyl-3-nonyl-6a...)
Affinity DataKi:  0.520nMAssay Description:Ability to bind with Cannabinoid receptor 2 using [H]CP 55,940 as radioligand from cloned human receptor preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat brain membraneMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataKi:  0.690nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptorMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50053357((6aR,10aR)-9-Hydroxymethyl-6,6-dimethyl-3-nonyl-6a...)
Affinity DataKi:  0.730nMAssay Description:Compound was evaluated for Pharmacological response in the Cannabinoid receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50067499((6aR,10aR)-3(1,1-dimethylheptyl)-9-hydroxymethyl)-...)
Affinity DataKi:  0.730nMAssay Description:Binding affinity of the compound for the Cannabinoid receptor using [3H]- CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50053359((6aR,10aR)-6,6,9-Trimethyl-3-nonyl-6a,7,10,10a-tet...)
Affinity DataKi:  0.770nMAssay Description:Compound was evaluated for Pharmacological response in the Cannabinoid receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50067735((6aR,10aR)-3-(1,1-Dimethyl-heptyl)-6,6,9-trimethyl...)
Affinity DataKi:  0.770nMAssay Description:Binding affinity of the compound for the cannabinoid brain receptor (CB1) using [3H]- CP-55,940More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50401063(CHEMBL2206834)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50401063(CHEMBL2206834)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50454329(CHEMBL2112647)
Affinity DataKi:  1.20nMAssay Description:Ability to bind with Cannabinoid receptor 1 using [H]CP-55940 as radioligand in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50330773(((6aR,10aR)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50401059(CHEMBL2206838)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to human CB1 receptor by filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Clemson University

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to displace [3H]CP-55,940 from CB1 receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50401058(CHEMBL2206839)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50323910(2-((1S,3R)-3-hydroxycyclohexyl)-5-(2-methyloctan-2...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50401070(CHEMBL2206856)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50401066(CHEMBL2206860)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50401067(CHEMBL2206859)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50401059(CHEMBL2206838)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50401067(CHEMBL2206859)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50401062(CHEMBL2206835)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50454328(CHEMBL2112646)
Affinity DataKi:  2.90nMAssay Description:Ability to bind with Cannabinoid receptor 2 using [H]CP 55,940 as radioligand from cloned human receptor preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50287933((6aR,10aR)-3-(1,1-Dimethyl-heptyl)-6,6,9-trimethyl...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50401071(CHEMBL2206855)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50401047(CHEMBL2206850)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50192607((5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl)(napht...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]CP 55940 from human cloned CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50192589((5-(2-ethylphenyl)-1-pentyl-1H-pyrrol-3-yl)(naphth...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]CP 55940 from human cloned CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50180036((6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetra...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50192595(CHEMBL220180 | JWH-370 | naphthalen-1-yl(1-pentyl-...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]CP 55940 from human cloned CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50192601((5-(2-chlorophenyl)-1-pentyl-1H-pyrrol-3-yl)(napht...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]CP 55940 from human cloned CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50401051(CHEMBL2206846)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50192595(CHEMBL220180 | JWH-370 | naphthalen-1-yl(1-pentyl-...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]CP 55940 from CB1 receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50192603(CHEMBL385940 | JWH-145 | naphthalen-1-yl(1-pentyl-...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]CP 55940 from human cloned CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50401061(CHEMBL2206836)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50170357(2-(2-Chloro-phenyl)-1-(1-pentyl-1H-indol-3-yl)-eth...)
Affinity DataKi:  7nMAssay Description:Binding affinity to displace [3H]CP-55,940 from cloned human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50192588((1-hexyl-5-phenyl-1H-pyrrol-3-yl)(naphthalen-1-yl)...)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]CP 55940 from human cloned CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50401071(CHEMBL2206855)
Affinity DataKi:  7.20nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50192607((5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl)(napht...)
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H]CP 55940 from CB1 receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50192601((5-(2-chlorophenyl)-1-pentyl-1H-pyrrol-3-yl)(napht...)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]CP 55940 from CB1 receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50170357(2-(2-Chloro-phenyl)-1-(1-pentyl-1H-indol-3-yl)-eth...)
Affinity DataKi:  8nMAssay Description:Binding affinity to displace [3H]CP-55,940 from CB1 receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50192610(CHEMBL384897 | JWH-372 | naphthalen-1-yl(1-pentyl-...)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]CP 55940 from human cloned CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50170337(2-(2-Bromo-phenyl)-1-(1-pentyl-1H-indol-3-yl)-etha...)
Affinity DataKi:  8.40nMAssay Description:Binding affinity to displace [3H]CP-55,940 from CB1 receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Clemson University

Curated by ChEMBL
LigandPNGBDBM50401066(CHEMBL2206860)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells after 1 hr by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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