Affinity DataKi: 0.220nMAssay Description:Inhibition of human recombinant GSK3beta using biotin- AAEELDSRAGS(PO3H2)PQL as substrate and [gamma32P]ATP after 20 mins by scintillation proximity ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Affinity DataKi: 0.300nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Affinity DataKi: 0.320nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Affinity DataKi: 0.340nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of human recombinant GSK3beta using biotin- AAEELDSRAGS(PO3H2)PQL as substrate and [gamma32P]ATP after 20 mins by scintillation proximity ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Affinity DataKi: 0.410nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...More data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Inhibition of human recombinant GSK3beta using biotin- AAEELDSRAGS(PO3H2)PQL as substrate and [gamma32P]ATP after 20 mins by scintillation proximity ...More data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Inhibition of human recombinant GSK3beta using biotin- AAEELDSRAGS(PO3H2)PQL as substrate and [gamma32P]ATP after 20 mins by scintillation proximity ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Affinity DataKi: 0.480nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Affinity DataKi: 0.670nMAssay Description:Inhibition of human recombinant GSK3beta using biotin- AAEELDSRAGS(PO3H2)PQL as substrate and [gamma32P]ATP after 20 mins by scintillation proximity ...More data for this Ligand-Target Pair
Affinity DataKi: 0.990nMAssay Description:Inhibition of human recombinant GSK3beta using biotin- AAEELDSRAGS(PO3H2)PQL as substrate and [gamma32P]ATP after 20 mins by scintillation proximity ...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of human recombinant GSK3beta using biotin- AAEELDSRAGS(PO3H2)PQL as substrate and [gamma32P]ATP after 20 mins by scintillation proximity ...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of human recombinant GSK3beta using biotin- AAEELDSRAGS(PO3H2)PQL as substrate and [gamma32P]ATP after 20 mins by scintillation proximity ...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of human recombinant GSK3beta using biotin- AAEELDSRAGS(PO3H2)PQL as substrate and [gamma32P]ATP after 20 mins by scintillation proximity ...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of human recombinant GSK3beta using biotin- AAEELDSRAGS(PO3H2)PQL as substrate and [gamma32P]ATP after 20 mins by scintillation proximity ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Affinity DataKi: 2.37nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Affinity DataKi: 3.10nMAssay Description:In vitro binding affinity at 5-HT1A receptor by measuring its ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocam...More data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Inhibition of human recombinant GSK3beta using biotin- AAEELDSRAGS(PO3H2)PQL as substrate and [gamma32P]ATP after 20 mins by scintillation proximity ...More data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Displacement of [125I]-IL8 from human CXCR2 transfected in HEK293 cells after 4 hrs by microbeta counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Inhibition of human recombinant GSK3beta using biotin- AAEELDSRAGS(PO3H2)PQL as substrate and [gamma32P]ATP after 20 mins by scintillation proximity ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Preclinical R & D, Astra Arcus
Curated by PDSP Ki Database
Affinity DataKi: 4.70nMAssay Description:Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Inhibition of human recombinant GSK3beta using biotin- AAEELDSRAGS(PO3H2)PQL as substrate and [gamma32P]ATP after 20 mins by scintillation proximity ...More data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Inhibition of human recombinant GSK3beta using biotin- AAEELDSRAGS(PO3H2)PQL as substrate and [gamma32P]ATP after 20 mins by scintillation proximity ...More data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysisMore data for this Ligand-Target Pair