Compile Data Set for Download or QSAR
maximum 50k data
Found 2012 with Last Name = 'katz' and Initial = 'b'
TargetEstrogen receptor beta(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133069(3'-Ethylamino-[1,1';2',1'']terphenyl-4'-carbaldehy...)
Affinity DataKi:  0.0480nMAssay Description:Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50104326(4-{3-(4-hydroxy-phenyl)-4-ethyl-5-[4-(2-piperidin-...)
Affinity DataKi:  0.0600nMAssay Description:Displacement of [3H]-estradiol from Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238727(CHEMBL4065838)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50133070(CHEMBL335465 | [1,1';2',1'']Terphenyl-4'-carbaldeh...)
Affinity DataKi:  0.150nMAssay Description:Relative binding affinity for human estrogen receptor alpha compared to [3H]-estradiolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238724(CHEMBL4060067)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133070(CHEMBL335465 | [1,1';2',1'']Terphenyl-4'-carbaldeh...)
Affinity DataKi:  0.270nMAssay Description:Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238716(CHEMBL4079530)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238726(CHEMBL4083780)
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238743(CHEMBL4070669)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238720(CHEMBL4102857)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50104326(4-{3-(4-hydroxy-phenyl)-4-ethyl-5-[4-(2-piperidin-...)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]-estradiol from Estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238742(CHEMBL4062045)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238739(CHEMBL4079644)
Affinity DataKi:  0.370nMAssay Description:Inhibition constant was evaluated against Histamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238733(CHEMBL4099302)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238717(CHEMBL4097562)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238737(CHEMBL4083658)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50104329(4-{3-Ethyl-5-phenyl-4-[4-(2-piperidin-1-yl-ethoxy)...)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]-estradiol from Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238738(CHEMBL4060817)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238740(CHEMBL4078577)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238728(CHEMBL4089824)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50104324(4-{5-(4-hydroxy-phenyl)-4-methyl-3-[4-(2-piperidin...)
Affinity DataKi:  0.470nMAssay Description:Displacement of [3H]-estradiol from Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50133069(3'-Ethylamino-[1,1';2',1'']terphenyl-4'-carbaldehy...)
Affinity DataKi:  0.470nMAssay Description:Relative binding affinity for human estrogen receptor alpha compared to [3H]-estradiolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101871(3-[3-(3-Benzyl-5-carbamimidoyl-1H-indol-2-yl)-5-br...)
Affinity DataKi:  0.5nMAssay Description:Inhibitory activity against Coagulation factor X in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101882(CHEMBL53829 | Phosphoric acid mono-{2-[3-(3-benzyl...)
Affinity DataKi:  0.5nMAssay Description:Inhibitory activity against Coagulation factor X in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50180517(2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-3'-ca...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to plasma kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238719(CHEMBL4073395)
Affinity DataKi:  0.570nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238735(CHEMBL4100247)
Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101881(4-[3-(3-Benzyl-5-carbamimidoyl-1H-indol-2-yl)-5-br...)
Affinity DataKi:  0.700nMAssay Description:Inhibitory activity against Coagulation factor X in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238725(CHEMBL4081283)
Affinity DataKi:  0.710nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238715(CHEMBL4098470)
Affinity DataKi:  0.710nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238729(CHEMBL4098232)
Affinity DataKi:  0.710nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238714(CHEMBL4081969)
Affinity DataKi:  0.740nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50104325(4-[5-(4-hydroxy-phenyl)-4-ethyl-3-(4-methoxy-pheny...)
Affinity DataKi:  0.910nMAssay Description:Displacement of [3H]-estradiol from Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM16303(2-(1H-1,3-benzodiazol-2-ylmethyl)-1H-1,3-benzodiaz...)
Affinity DataKi:  1nMAssay Description:Binding affinity to FXa in presence of Zn2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50176252(2-((6-fluoro-1H-benzo[d]imidazol-2-yl)methyl)-1H-b...)
Affinity DataKi:  1nMAssay Description:Binding affinity to FXa in presence of Zn2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238736(CHEMBL1091535 | GW7604)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50181921(2-[5-(5-carbamimidoyl-1H-indol-2-yl)-6-hydroxy-3'-...)
Affinity DataKi:  1nMAssay Description:Binding affinity to factor7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50176251(2-((6-chloro-1H-benzo[d]imidazol-2-yl)methyl)-1H-b...)
Affinity DataKi:  1nMAssay Description:Binding affinity to FXa in presence of Zn2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM16303(2-(1H-1,3-benzodiazol-2-ylmethyl)-1H-1,3-benzodiaz...)
Affinity DataKi:  1nMAssay Description:Binding affinity to thrombin in presence of Zn2+More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238721(CHEMBL4071436)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50133071(3'-Hydroxy-[1,1';2',1'']terphenyl-4'-carbaldehyde ...)
Affinity DataKi:  1.10nMAssay Description:Relative binding affinity for human estrogen receptor alpha compared to [3H]-estradiolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14338(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-nit...)
Affinity DataKi:  1.30nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238731(CHEMBL4091563)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238722(CHEMBL4068722)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238734(CHEMBL4101656)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133071(3'-Hydroxy-[1,1';2',1'']terphenyl-4'-carbaldehyde ...)
Affinity DataKi:  1.70nMAssay Description:Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238730(CHEMBL4099166)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50181916(CHEMBL206168 | [5-(5-carbamimidoyl-1H-benzoimidazo...)
Affinity DataKi:  2nMAssay Description:Binding affinity to factor7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50180400(2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-6,2'-...)
Affinity DataKi:  2nMAssay Description:Binding affinity to F7a/TF complexMore data for this Ligand-Target Pair
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