TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataKi: 8.80nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in human erythrocyteMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in human erythrocyteMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in human erythrocyteMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in human erythrocyteMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in Cellulomonas spMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in Cellulomonas spMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of mouse brain AChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of mouse brain AChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in Cellulomonas spMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in human erythrocyteMore data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of mouse brain AChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of mouse brain AChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in human erythrocyteMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in human erythrocyteMore data for this Ligand-Target Pair
Affinity DataIC50: 330nMpH: 4.5 T: 2°CAssay Description:Compounds were dissolved in dimethylsulfoxide (DMSO), and further diluted in 0.1 M sodium acetate buffer (with 150 mM sodium chloride, pH 4.5). The s...More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in Cellulomonas spMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMpH: 4.5 T: 2°CAssay Description:Compounds were dissolved in dimethylsulfoxide (DMSO), and further diluted in 0.1 M sodium acetate buffer (with 150 mM sodium chloride, pH 4.5). The s...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in human erythrocyteMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in human erythrocyteMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of mouse brain AChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMpH: 4.5 T: 2°CAssay Description:Compounds were dissolved in dimethylsulfoxide (DMSO), and further diluted in 0.1 M sodium acetate buffer (with 150 mM sodium chloride, pH 4.5). The s...More data for this Ligand-Target Pair
Affinity DataIC50: 480nMpH: 4.5 T: 2°CAssay Description:Compounds were dissolved in dimethylsulfoxide (DMSO), and further diluted in 0.1 M sodium acetate buffer (with 150 mM sodium chloride, pH 4.5). The s...More data for this Ligand-Target Pair
Affinity DataIC50: 490nMpH: 4.5 T: 2°CAssay Description:Compounds were dissolved in dimethylsulfoxide (DMSO), and further diluted in 0.1 M sodium acetate buffer (with 150 mM sodium chloride, pH 4.5). The s...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMpH: 4.5 T: 2°CAssay Description:Compounds were dissolved in dimethylsulfoxide (DMSO), and further diluted in 0.1 M sodium acetate buffer (with 150 mM sodium chloride, pH 4.5). The s...More data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair