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Found 331 with Last Name = 'kleinert' and Initial = 'hd'
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022633(CHEMBL3142281 | [1-[1-(1-Cyclohexylmethyl-2,3-dihy...)
Affinity DataIC50:  0.200nMAssay Description:In vitro inhibitory activity was tested against purified human renal reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022635(CHEMBL3142255 | {1-[1-(1-Cyclohexylmethyl-2,3-dihy...)
Affinity DataIC50:  0.25nMAssay Description:In vitro inhibitory activity was tested against purified human renal reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022647(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  0.290nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014078(A-62198 | CHEMBL291591 | N-{(S)-1-[(S)-1-((1S,2R,3...)
Affinity DataIC50:  0.290nMpH: 7.4Assay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022619(CHEMBL3348544 | N-[1-(1-Cyclohexylmethyl-2,3-dihyd...)
Affinity DataIC50:  0.300nMAssay Description:In vitro inhibitory activity was tested against purified human renal reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022597(CHEMBL3142268 | {1-[1-(1-Cyclohexylmethyl-2,3-dihy...)
Affinity DataIC50:  0.300nMAssay Description:In vitro inhibitory activity was tested against purified human renal reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022646(CHEMBL307917 | Morpholine-4-carboxylic acid {1-[1-...)
Affinity DataIC50:  0.300nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014084((R)-2-Benzyl-N*1*-[(S)-1-[(1S,2R)-1-cyclohexylmeth...)
Affinity DataIC50:  0.330nMpH: 7.4Assay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022650(CHEMBL75117 | Morpholine-4-carboxylic acid {1-[1-(...)
Affinity DataIC50:  0.350nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014084((R)-2-Benzyl-N*1*-[(S)-1-[(1S,2R)-1-cyclohexylmeth...)
Affinity DataIC50:  0.370nMpH: 6.5Assay Description:Inhibitory activity against purified human renal renin at pH 6.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280221((1S,2S,3R)-2-Phenyl-3-(propane-2-sulfonyl)-cyclopr...)
Affinity DataIC50:  0.370nMpH: 6.0Assay Description:In vitro inhibition of human plasma renin at PH 7.4More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280229((1S,2S,3R)-2-Phenyl-3-(propane-2-sulfonyl)-cyclopr...)
Affinity DataIC50:  0.380nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017780(CHEMBL284451 | {1-[1-(4-Azido-1-cyclohexylmethyl-2...)
Affinity DataIC50:  0.400nMpH: 6.0Assay Description:Inhibitory activity against purified human plasma renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017780(CHEMBL284451 | {1-[1-(4-Azido-1-cyclohexylmethyl-2...)
Affinity DataIC50:  0.400nMpH: 6.0Assay Description:Inhibitory activity against purified human renal renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022643(4-Hydroxy-piperidine-1-carboxylic acid {1-[1-(1-cy...)
Affinity DataIC50:  0.420nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280237((1S,2R,3S)-2-(2-Methoxymethoxy-ethanesulfonyl)-3-p...)
Affinity DataIC50:  0.480nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014081((R)-2-Benzyl-N*1*-[(S)-1-[(1S,2R)-1-cyclohexylmeth...)
Affinity DataIC50:  0.490nMpH: 6.5Assay Description:Inhibitory activity against purified human renal renin at pH 6.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022603(CHEMBL3348551 | {1-[1-(1-Cyclohexylmethyl-2,3-dihy...)
Affinity DataIC50:  0.5nMAssay Description:In vitro inhibitory activity was tested against purified human renal reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022649(CHEMBL76458 | N-[1-(1-Cyclohexylmethyl-2,3-dihydro...)
Affinity DataIC50:  0.5nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022628(CHEMBL3142261 | {1-[1-(1-Cyclohexylmethyl-2,3-dihy...)
Affinity DataIC50:  0.5nMAssay Description:In vitro inhibitory activity was tested against purified human renal reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022599(CHEMBL3142262 | {1-[1-(1-Cyclohexylmethyl-2,3-dihy...)
Affinity DataIC50:  0.5nMAssay Description:In vitro inhibitory activity was tested against purified human renal reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017783(CHEMBL440779 | N-{1-[1-(4-Azido-1-cyclohexylmethyl...)
Affinity DataIC50:  0.550nMpH: 6.0Assay Description:Inhibitory activity against purified human plasma renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022645(CHEMBL75510 | N-[1-(1-Cyclohexylmethyl-2,3-dihydro...)
Affinity DataIC50:  0.550nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017783(CHEMBL440779 | N-{1-[1-(4-Azido-1-cyclohexylmethyl...)
Affinity DataIC50:  0.550nMpH: 6.0Assay Description:Inhibitory activity against purified human plasma renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014084((R)-2-Benzyl-N*1*-[(S)-1-[(1S,2R)-1-cyclohexylmeth...)
Affinity DataIC50:  0.570nMpH: 7.4Assay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022651(CHEMBL306274 | Morpholine-4-carboxylic acid {1-[1-...)
Affinity DataIC50:  0.580nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280235((1S,2S,3R)-2-Phenyl-3-(propane-2-sulfonyl)-cyclopr...)
Affinity DataIC50:  0.590nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014073((R)-2-Benzyl-N*1*-[(S)-1-[(1S,2R)-1-cyclohexylmeth...)
Affinity DataIC50:  0.590nMpH: 6.5Assay Description:Inhibitory activity against purified human renal renin at pH 6.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022595(CHEMBL3348552 | {1-[1-(1-Cyclohexylmethyl-2,3-dihy...)
Affinity DataIC50:  0.600nMAssay Description:In vitro inhibitory activity was tested against purified human renal reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022598(CHEMBL3348548 | {1-[1-(1-Cyclohexylmethyl-2,3-dihy...)
Affinity DataIC50:  0.600nMAssay Description:In vitro inhibitory activity was tested against purified human renal reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50011231(2-Benzyl-N-{1-[1-cyclohexylmethyl-2-(3-ethyl-2-oxo...)
Affinity DataIC50:  0.600nMpH: 6.5Assay Description:Compound was evaluated for the inhibitory concentration against purified human renal renin at pH 6.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280224((1S,2R,3S)-2-Methanesulfonyl-3-phenyl-cyclopropane...)
Affinity DataIC50:  0.630nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280222((1S,2R,3S)-2-Ethenesulfonyl-3-phenyl-cyclopropanec...)
Affinity DataIC50:  0.630nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022644(CHEMBL73712 | Piperazine-1-carboxylic acid {1-[1-(...)
Affinity DataIC50:  0.650nMpH: 6.0Assay Description:Inhibition of human plasma renin (pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022643(4-Hydroxy-piperidine-1-carboxylic acid {1-[1-(1-cy...)
Affinity DataIC50:  0.680nMpH: 7.4Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017782(CHEMBL280744 | Tetrahydro-pyran-4-carboxylic acid ...)
Affinity DataIC50:  0.700nMpH: 6.0Assay Description:Inhibitory activity against purified human plasma renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280227((1S,2R,3S)-2-(2-Morpholin-4-yl-2-oxo-ethyl)-3-phen...)
Affinity DataIC50:  0.700nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022630(CHEMBL3348531 | Cyclohexanecarboxylic acid {1-[1-(...)
Affinity DataIC50:  0.700nMAssay Description:In vitro inhibitory activity was tested against purified human renal reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50405479(CHEMBL2028988)
Affinity DataIC50:  0.700nMAssay Description:Inhibition against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022637(2-(2-Acetylamino-3-phenyl-propionylamino)-N-(1-cyc...)
Affinity DataIC50:  0.75nMAssay Description:In vitro inhibitory activity was tested against purified human renal reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022653(CHEMBL309345 | Morpholine-4-carboxylic acid [1-[1-...)
Affinity DataIC50:  0.760nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280219(3-Benzenesulfonyl-2-benzyl-N-[(S)-1-((1S,2R,3S)-1-...)
Affinity DataIC50:  0.770nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280231((1S,2R,3R)-2-Cyclohexyl-3-(propane-2-sulfonyl)-cyc...)
Affinity DataIC50:  0.790nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022641(2-Benzylidene-N-[1-(1-cyclohexylmethyl-2,3-dihydro...)
Affinity DataIC50:  0.790nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022654(CHEMBL265485 | Morpholine-4-carboxylic acid 1-[1-(...)
Affinity DataIC50:  0.820nMpH: 6.0Assay Description:Inhibition of human plasma renin (pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014079((R)-2-Benzyl-N*1*-[(S)-1-[(1S,2R)-1-cyclohexylmeth...)
Affinity DataIC50:  0.850nMpH: 6.5Assay Description:Inhibitory activity against purified human renal renin at pH 6.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046796((S)-N-[(S)-1-((1S,2R,3S)-1-Cyclohexylmethyl-2,3-di...)
Affinity DataIC50:  0.870nMpH: 7.4Assay Description:In vitro inhibition of human plasma renin at PH 7.4More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022650(CHEMBL75117 | Morpholine-4-carboxylic acid {1-[1-(...)
Affinity DataIC50:  0.890nMpH: 7.4Assay Description:Inhibition of human plasma renin (pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006147(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  0.900nMpH: 7.4Assay Description:In vitro potency against purified renin at a pH of 6.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006157(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  0.900nMpH: 6.0Assay Description:In vitro potency against plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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