Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Compound was tested for the inhibition of Delta-(24)-sterol reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMpH: 4.5Assay Description:Binding affinity towards Dopamine beta hydroxylase using tyramine substrate at pH 4.5 in the absence of fumarateMore data for this Ligand-Target Pair
Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Compound was tested for the inhibition of Delta-(24)-sterol reductaseMore data for this Ligand-Target Pair
Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Compound was tested for the inhibition of delta24-sterol reductaseMore data for this Ligand-Target Pair
Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Compound was tested for the inhibition of delta24-sterol reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 41nMpH: 4.5Assay Description:Binding affinity towards Dopamine beta hydroxylase using tyramine substrate at pH 4.5 in the absence of fumarateMore data for this Ligand-Target Pair
Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Compound was tested for the inhibition of delta24-sterol reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 55nMpH: 4.5Assay Description:Compound was evaluated for the inhibition of Dopamine beta hydroxylase at pH 4.5More data for this Ligand-Target Pair
Affinity DataKi: 55nMpH: 4.5Assay Description:Binding affinity towards Dopamine beta hydroxylase using tyramine substrate at pH 4.5 in the absence of fumarateMore data for this Ligand-Target Pair
Affinity DataKi: 149nMAssay Description:Compound was evaluated for the inhibition of Dopamine beta hydroxylase at pH 4.5More data for this Ligand-Target Pair
Affinity DataKi: 149nMpH: 4.5Assay Description:Binding affinity towards Dopamine beta hydroxylase using tyramine substrate at pH 4.5 in the absence of fumarateMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Reversible binding potential for rat ATP-Citrate Lyase as carbon-carbon bond cleavage activity in citrate substrateMore data for this Ligand-Target Pair
Affinity DataKi: 344nMpH: 6.6Assay Description:Compound was evaluated for the inhibition of Dopamine beta hydroxylase at pH 6.6More data for this Ligand-Target Pair
Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Compound was tested for the inhibition of Delta-(24)-sterol reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+4nMAssay Description:Reversible binding potential for rat ATP-Citrate Lyase as carbon-carbon bond cleavage activity in citrate substrateMore data for this Ligand-Target Pair
Affinity DataKi: 2.90E+4nMAssay Description:Reversible binding potential for rat ATP-Citrate Lyase as carbon-carbon bond cleavage activity in citrate substrateMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+4nMAssay Description:Reversible binding potential for rat ATP-Citrate Lyase as carbon-carbon bond cleavage activity in citrate substrateMore data for this Ligand-Target Pair
Affinity DataKi: 3.50E+4nMAssay Description:KI value was determined from plots of 1/kinact(observed) vs 1/[inhibitor]More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMpH: 4.5Assay Description:Compound was evaluated for the inhibition of Dopamine beta hydroxylase at pH 6.6More data for this Ligand-Target Pair
Affinity DataKi: 5.70E+4nMAssay Description:KI value was determined from plots of 1/kinact(observed) vs 1/[inhibitor]More data for this Ligand-Target Pair
Affinity DataKi: 5.70E+4nMAssay Description:KI value was determined from plots of 1/kinact(observed) vs 1/[inhibitor]More data for this Ligand-Target Pair
Affinity DataKi: 5.80E+4nMAssay Description:Reversible binding potential for rat ATP-Citrate Lyase as carbon-carbon bond cleavage activity in citrate substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+5nMAssay Description:Reversible binding potential for rat ATP-Citrate Lyase as carbon-carbon bond cleavage activity in citrate substrateMore data for this Ligand-Target Pair
Affinity DataKi: 2.95E+5nMAssay Description:Reversible binding potential for rat ATP-Citrate Lyase as carbon-carbon bond cleavage activity in citrate substrateMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+5nMAssay Description:Reversible binding potential for rat ATP-Citrate Lyase as carbon-carbon bond cleavage activity in citrate substrateMore data for this Ligand-Target Pair
Affinity DataKi: 4.00E+5nMAssay Description:Reversible binding potential for rat ATP-Citrate Lyase as carbon-carbon bond cleavage activity in citrate substrateMore data for this Ligand-Target Pair
Affinity DataKi: 4.80E+5nMAssay Description:Reversible binding potential for rat ATP-Citrate Lyase as carbon-carbon bond cleavage activity in citrate substrateMore data for this Ligand-Target Pair
Affinity DataKi: 5.20E+5nMpH: 5.0Assay Description:KI value was determined from plots of 1/kinact(observed) vs 1/[inhibitor]; Apparent values at pH 5.0, 0.24 mM O2More data for this Ligand-Target Pair
Affinity DataKi: 7.16E+5nMpH: 6.6Assay Description:Compound was evaluated for the inhibition of Dopamine beta hydroxylase at pH 4.5More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Reversible binding potential for rat ATP-Citrate Lyase as carbon-carbon bond cleavage activity in citrate substrateMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Reversible binding potential for rat ATP-Citrate Lyase as carbon-carbon bond cleavage activity in citrate substrateMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Reversible binding potential for rat ATP-Citrate Lyase as carbon-carbon bond cleavage activity in citrate substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+6nMAssay Description:KI value was determined from plots of 1/kinact(observed) vs 1/[inhibitor]More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (0.060-0.0877).More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (0.42-1.1).More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value ranges from 0.4-1.1More data for this Ligand-Target Pair
Affinity DataIC50: 860nMAssay Description:Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.More data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value ranges from 1.1-1.4More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (1.0-1.9)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (0.9-2.2)More data for this Ligand-Target Pair
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
Affinity DataIC50: 1.95E+3nMAssay Description:Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.More data for this Ligand-Target Pair