TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Boehringer Ingelheim (Canada)
Curated by ChEMBL
Boehringer Ingelheim (Canada)
Curated by ChEMBL
Affinity DataKi: 600nMAssay Description:The apparent Ki value against NS3-4Apep proteaseMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Boehringer Ingelheim (Canada)
Curated by ChEMBL
Boehringer Ingelheim (Canada)
Curated by ChEMBL
Affinity DataKi: 1.40E+4nMAssay Description:The apparent Ki value against NS3-4Apep proteaseMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Chul Research Center
Curated by ChEMBL
Chul Research Center
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrateMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Chul Research Center
Curated by ChEMBL
Chul Research Center
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrateMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Chul Research Center
Curated by ChEMBL
Chul Research Center
Curated by ChEMBL
Affinity DataIC50: 172nMAssay Description:In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrateMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Chul Research Center
Curated by ChEMBL
Chul Research Center
Curated by ChEMBL
Affinity DataIC50: 192nMAssay Description:In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrateMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center
Curated by ChEMBL
Chul Research Center
Curated by ChEMBL
Affinity DataIC50: 218nMAssay Description:In vitro inhibition of human Steroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrateMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Chul Research Center
Curated by ChEMBL
Chul Research Center
Curated by ChEMBL
Affinity DataIC50: 387nMAssay Description:In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Chul Research Center
Curated by ChEMBL
Chul Research Center
Curated by ChEMBL
Affinity DataIC50: 437nMAssay Description:In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrateMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of DNMT1 (unknown origin) using biotinylated substrate using [3H]-SAM after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center
Curated by ChEMBL
Chul Research Center
Curated by ChEMBL
Affinity DataIC50: 709nMAssay Description:In vitro inhibition of human tSteroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrate.More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center
Curated by ChEMBL
Chul Research Center
Curated by ChEMBL
Affinity DataIC50: 981nMAssay Description:In vitro inhibition of human tSteroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrate.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center
Curated by ChEMBL
Chul Research Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibition of human tSteroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrate.More data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center
Curated by ChEMBL
Chul Research Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibition of human tSteroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrate.More data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Boehringer Ingelheim (Canada)
Curated by ChEMBL
Boehringer Ingelheim (Canada)
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of DNMT3A/3L (unknown origin) using poly(2'-deoxyinosinic-2'-deoxycytidylic acid) as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair