Compile Data Set for Download or QSAR
maximum 50k data
Found 174 with Last Name = 'lee' and Initial = 'yk'
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231280(1-(3-cyano-4-fluorophenyl)-6-[4-(3-dimethylaminome...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM12676(1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-N-[...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM12676(1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-N-[...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231282(1-(3-aminobenzo[d]isoxazol-5-yl)-6-[4-(3-dimethyla...)
Affinity DataKi:  3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231275(1-(3-aminobenzo[d]isoxazol-5-yl)-7-fluoro-6-[2-flu...)
Affinity DataKi:  4.10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231284(1-(3-aminobenzo[d]isoxazol-5-yl)-6-[4-(2-dimethyla...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231271(1-(3-aminobenzo[d]isoxazol-5-yl)-6-{4-[(2-dimethyl...)
Affinity DataKi:  4.90nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231279(1-(3-aminobenzo[d]isoxazol-5-yl)-6-{4-[(3-dimethyl...)
Affinity DataKi:  5.20nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231283(1-(3-aminobenzo[d]isoxazol-5-yl)-7-fluoro-6-[2-flu...)
Affinity DataKi:  6.40nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50086717(JNJ-39439335 | Mavatrep)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]-RTX from human TRPV1 transfected in HEK293 cells after 60 mins by scintillation spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231270(1-(3-aminobenzo[d]isoxazol-5-yl)-6-(2'-dimethylami...)
Affinity DataKi:  8.10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231272(1-(3-amino-1,2-benzisoxazol-5-yl)-6-(4-{2-[(dimeth...)
Affinity DataKi:  15.9nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231269(1-{4-[1-(3-aminobenzo[d]isoxazol-5-yl)-7-fluoro-3-...)
Affinity DataKi:  22.9nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231274(1-{4-[1-(3-aminobenzo[d]isoxazol-5-yl)-7-fluoro-3-...)
Affinity DataKi:  26nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231286(1-{4-[1-(3-aminomethylphenyl)-7-fluoro-3-methyl-1H...)
Affinity DataKi:  124nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231268(1-(3-aminobenzo[d]isoxazol-5-yl)-6-[4-(4-dimethyla...)
Affinity DataKi:  147nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231278(1-{4-[1-(3-aminomethylphenyl)-7-fluoro-3-methyl-1H...)
Affinity DataKi:  223nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231281(1-(3-aminobenzo[d]isoxazol-5-yl)-6-{4-[(2-dimethyl...)
Affinity DataKi:  231nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231267(1-(3-aminobenzo[d]isoxazol-5-yl)-6-{4-[(2-dimethyl...)
Affinity DataKi:  690nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231266(1-(3-aminobenzo[d]isoxazol-5-yl)-6-[4-(3-dimethyla...)
Affinity DataKi:  2.26E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231273(1-{4-[1-(3-aminomethylphenyl)-3-methyl-1H-indazol-...)
Affinity DataKi:  6.85E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50231265(1-{4-[1-(3-aminomethylphenyl)-3-methyl-1H-indazol-...)
Affinity DataKi: >1.44E+4nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM193240(US9193736, 164)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human recombinant full length PDE10A expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM193125(US9193736, 41)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human recombinant full length PDE10A expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM193124(US9193736, 40)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human recombinant full length PDE10A expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50086728(CHEMBL3426347)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM193124(US9193736, 40)
Affinity DataIC50:  2nMAssay Description:Inhibition of rat PDE10A by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM193112(US9193736, 28)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human recombinant full length PDE10A expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM193120(US9193736, 36)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human recombinant full length PDE10A expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM193245(US9193736, 169)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human recombinant full length PDE10A expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50086744(CHEMBL3426376)
Affinity DataIC50:  2.80nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50086740(CHEMBL3426378)
Affinity DataIC50:  2.80nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM193096(US9193736, 12)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant full length PDE10A expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM193244(US9193736, 168)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human recombinant full length PDE10A expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM193186(US9193736, 102)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human recombinant full length PDE10A expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM193184(US9193736, 100)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of human recombinant full length PDE10A expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50086739(CHEMBL3426379)
Affinity DataIC50:  4.5nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50086717(JNJ-39439335 | Mavatrep)
Affinity DataIC50:  4.60nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50086716(CHEMBL3426361)
Affinity DataIC50:  4.90nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM27135(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-1,3-benzodiazo...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly (ADP-ribose) onto histone protein after 60 mins by TACS-Sapphire...More data for this Ligand-Target Pair
LigandPNGBDBM50086713(CHEMBL3426364)
Affinity DataIC50:  5.70nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50086714(CHEMBL3426363)
Affinity DataIC50:  5.90nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50086742(CHEMBL3426377)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50086749(CHEMBL3426369)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50086717(JNJ-39439335 | Mavatrep)
Affinity DataIC50:  6.80nMpH: 5.0Assay Description:Antagonist activity at recombinant human TRPV1 expressed in HEK293 cells assessed as inhibition of pH 5-induced current measured for 150 secs by patc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50086864(CHEMBL3426367)
Affinity DataIC50:  7nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50086848(CHEMBL3426368)
Affinity DataIC50:  7nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50086745(CHEMBL3426375)
Affinity DataIC50:  7nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM193138(US9193736, 54)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of human recombinant full length PDE10A expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50086748(CHEMBL3426370)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 174 total ) | Next | Last >>
Jump to: