TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0700nMAssay Description:Affinity of compound for D2 receptor in rat striatal membrane determined for agonist state (high affinity state, D2 High) [3H]quinpirole as radioliga...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Affinity of compound for D2 receptor in rat striatal membrane determined for agonist state (high affinity state, D2 High) [3H]quinpirole as radioliga...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Affinity of compound for D2 receptor in rat striatal membrane determined for agonist state (high affinity state, D2 High) [3H]quinpirole as radioliga...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Antagonistic activity towards dopamine D2 receptor using radioligand [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Inhibtion of [3H]-spiperone binding to rat striatal membrane Dopamine receptor D2 low affinity without GTP and sodiumMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Inhibition of [3H]-quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodiumMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Inhibtion of [3H]-spiperone binding to rat striatal membrane Dopamine receptor D2 low affinity without GTP and sodiumMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:In vitro binding affinity to rat hippocampal 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity at human Dopamine receptor D3 (hD3) using [3H]spiperone radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Affinity of compound for D2 receptor in rat striatal membrane determined for agonist state (high affinity state, D2 High) [3H]quinpirole as radioliga...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Inhibition of [3H]-quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodiumMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Inhibition of [3H]-quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodiumMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.220nMAssay Description:Antagonist activity against rat hippocampal tissue 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Antagonist activity against rat hippocampal tissue 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Inhibition of [3H]-quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodiumMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]citalopram form human SRET by liquid scintillation countingMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:In vitro binding affinity to rat hippocampal 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.350nMAssay Description:Agonistic activity towards dopamine D2 receptor using radioligand [3H]-quinpirole in rat striatal membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Affinity for the Human Dopamine receptor D3 was determined using membranes from CHO cells labeled with [3H]spiperoneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenatesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenatesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:In vitro binding affinity to rat hippocampal 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.410nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.430nMAssay Description:Antagonist activity against rat hippocampal tissue 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.440nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Compound was tested to inhibit Dopa accumulation in Dopamine receptor D3 at 10 mg/kg, scMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A r receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenatesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.510nMAssay Description:Affinity for Dopamine receptor D2 in rat striatal membranes for high agonist state using [3H]-quinpiroleMore data for this Ligand-Target Pair