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Found 170 with Last Name = 'martino' and Initial = 'br'
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200028(2-methoxy-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipy...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150141(2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataKi:  1.5nMAssay Description:In vitro binding affinity tested on HEK293 cells co-transfected with human D4.4 receptor using [3H]spiperone as a radioligand in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145073(5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity towards human D4.4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [125I]7-OH-PIPAT from human D2L receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150143(2-[4-(2,5-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataKi:  3.80nMAssay Description:In vitro binding affinity tested on HEK293 cells co-transfected with human D4.4 receptor using [3H]spiperone as a radioligand in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200037(2-(3',4',-5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200029(6-(4-((1H-benzo[d]imidazol-2-yl)methyl)piperazin-1...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200028(2-methoxy-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipy...)
Affinity DataKi:  27nMAssay Description:Displacement of [125I]7-OH-PIPAT from human D2L receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200043(3-methyl-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipyr...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145079(2-(4-Phenyl-piperazin-1-ylmethyl)-1H-benzoimidazol...)
Affinity DataKi:  33nMAssay Description:Binding affinity tested against D4.2 receptor in Chinese hamster ovary cell line (CHO cells) using [3H]spiperone as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145073(5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataKi:  120nMAssay Description:Binding affinity towards human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataKi:  160nMAssay Description:In vitro binding affinity tested on human Dopamine receptor D2 using [3H]spiperon as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145073(5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataKi:  200nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200066(CHEMBL220189 | N-(3',4',5',6'-tetrahydro-2'H-[2,4'...)
Affinity DataKi:  235nMAssay Description:Displacement of [125I]7-OH-PIPAT from human D2L receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200030(2-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'bipyridin...)
Affinity DataKi:  294nMAssay Description:Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145073(5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataKi:  300nMAssay Description:Binding affinity towards human Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200041(CHEMBL219261 | N-(2-methyl-4-fluorophenyl)-2-(1-ox...)
Affinity DataKi:  405nMAssay Description:Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145073(5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataKi:  560nMAssay Description:Binding affinity towards human Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200050(ABT-670 | CHEMBL219182 | methyl-N-(1-oxy-3',4',5',...)
Affinity DataKi:  1.45E+3nMAssay Description:Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200037(2-(3',4',-5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1...)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [125I]7-OH-PIPAT from human D2L receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200043(3-methyl-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipyr...)
Affinity DataKi:  3.50E+3nMAssay Description:Displacement of [125I]7-OH-PIPAT from human D2L receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200043(3-methyl-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipyr...)
Affinity DataKi:  3.50E+3nMAssay Description:Agonist activity at human D2 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200030(2-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'bipyridin...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]7-OH-PIPAT from human D2L receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200029(6-(4-((1H-benzo[d]imidazol-2-yl)methyl)piperazin-1...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human D2S receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200041(CHEMBL219261 | N-(2-methyl-4-fluorophenyl)-2-(1-ox...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]7-OH-PIPAT from human D2L receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200030(2-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'bipyridin...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human D2S receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200029(6-(4-((1H-benzo[d]imidazol-2-yl)methyl)piperazin-1...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]7-OH-PIPAT from human D2L receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200050(ABT-670 | CHEMBL219182 | methyl-N-(1-oxy-3',4',5',...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human D2S receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200041(CHEMBL219261 | N-(2-methyl-4-fluorophenyl)-2-(1-ox...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human D2S receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity tested on human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200050(ABT-670 | CHEMBL219182 | methyl-N-(1-oxy-3',4',5',...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]7-OH-PIPAT from human D2L receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataKi:  1.50E+4nMAssay Description:In vitro binding affinity tested on human Dopamine receptor D2 (long) using [3H]spiperon as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataKi:  5.10E+4nMAssay Description:In vitro binding affinity tested on human Dopamine receptor D2 (short) using [3H]spiperone as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataKi:  2.78E+6nMAssay Description:In vitro binding affinity tested on human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150143(2-[4-(2,5-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory concentration tested on human D4.4 receptor in HEK293 cells using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150141(2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory concentration tested on human D4.4 receptor in HEK293 cells using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human D4.4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human D2 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at human D4.4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataEC50:  5.80nMAssay Description:Agonist activity at human D2 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200037(2-(3',4',-5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human D4.4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200050(ABT-670 | CHEMBL219182 | methyl-N-(1-oxy-3',4',5',...)
Affinity DataEC50:  160nMAssay Description:Agonist activity at ferret D4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200041(CHEMBL219261 | N-(2-methyl-4-fluorophenyl)-2-(1-ox...)
Affinity DataEC50:  60nMAssay Description:Agonist activity at human D4.4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at ferret D2 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at ferret D4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200029(6-(4-((1H-benzo[d]imidazol-2-yl)methyl)piperazin-1...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at ferret D4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200028(2-methoxy-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipy...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human D2 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200026(2-[1-[2-(m-tolylamino)allyl]piperidin-4-yl]benzoni...)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human D4.4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200024(CHEMBL219565 | N-(2-methoxy-6-methylphenyl)-2-(1-o...)
Affinity DataEC50:  340nMAssay Description:Agonist activity at human D4.4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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