TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Displacement of [125I]IPT from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 0.171nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 0.530nMAssay Description:Displacement of [3H]paroxetine from SERTMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 0.870nMAssay Description:Displacement of [3H]WIN35428 from human cloned DAT receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Displacement of [125I]IDAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 0.980nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 1.25nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 1.49nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 1.65nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 1.65nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 1.65nMAssay Description:Displacement of [3H]paroxetine from SERTMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]MADAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]paroxetine from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 1.92nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 2.23nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 2.75nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Reversible competitive inhibition of human cathepsin K using fluorogenic AMC-derived peptide substrate assessed as reduction in residual activity pre...More data for this Ligand-Target Pair
Affinity DataKi: 3.57nMAssay Description:Displacement of (-)-[3H]pentazocine from sigma 1 receptor in rat cortical membranes after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 3.68nMAssay Description:Displacement of (-)-[3H]vesamicol from rat VAChT expressed in rat PC12 cells after 60 minsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 4.15nMAssay Description:Displacement of [3H]paroxetine from SERTMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Reversible competitive inhibition of human cathepsin L using fluorogenic AMC-derived peptide substrate assessed as reduction in residual activity pre...More data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine transporter (NET) of rat cortical homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 6.95nMAssay Description:Displacement of (-)-[3H]vesamicol from rat VAChT expressed in rat PC12 cells after 60 minsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 7.96nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [125I]IDAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Reversible competitive inhibition of human cathepsin K using fluorogenic AMC-derived peptide substrate assessed as reduction in residual activity pre...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]MADAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 10.3nMAssay Description:Displacement of [3H]paroxetine from SERTMore data for this Ligand-Target Pair
Affinity DataKi: 10.9nMAssay Description:Displacement of (-)-[3H]vesamicol from rat VAChT expressed in rat PC12 cells after 60 minsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nicotinic acetylcholine receptor in Wistar rat frontal cortex by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 12.8nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine transporter (NET) of rat cortical homogenatesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 13.2nMAssay Description:Displacement of (-)-[3H]pentazocine from sigma 1 receptor in rat cortical membranes after 120 minsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]MADAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nicotinic acetylcholine receptor in Wistar rat frontal cortex by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 15.8nMAssay Description:Displacement of (-)-[3H]vesamicol from rat VAChT expressed in rat PC12 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Reversible competitive inhibition of human cathepsin S using fluorogenic AMC-derived peptide substrate assessed as reduction in residual activity at ...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]WIN35428 from human cloned DAT receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 19.3nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
Affinity DataKi: 19.6nMAssay Description:Displacement of (-)-[3H]vesamicol from rat VAChT expressed in rat PC12 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Reversible competitive inhibition of human cathepsin S using fluorogenic AMC-derived peptide substrate assessed as reduction in residual activity at ...More data for this Ligand-Target Pair
Affinity DataKi: 28.4nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine transporter (NET) of rat cortical homogenatesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 34nMAssay Description:Displacement of [125I]IDAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair