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Found 149 with Last Name = 'moore' and Initial = 'pf'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50229040(CHEMBL156140)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50229041(CHEMBL351567)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50229038(CHEMBL345917)
Affinity DataIC50:  3.20nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331888(5-Chloro-2-oxo-3-(thiophene-2-carbonyl)-2,3-dihydr...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50218545(Nitraquazone)
Affinity DataIC50:  14nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012881(2-Methoxy-10H-phenothiazine | CHEMBL64404 | cid_74...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012860(1-Oxo-1,2-dihydro-6-oxa-10b-aza-aceanthrylene-2-ca...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50229040(CHEMBL156140)
Affinity DataIC50:  40nMAssay Description:Inhibition of phosphodiesterase 4 from rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012867(1-Oxo-1,2-dihydro-6-thia-10b-aza-aceanthrylene-2-c...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50229041(CHEMBL351567)
Affinity DataIC50:  70nMAssay Description:Inhibition of phosphodiesterase 4 from rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012846(4,8-Difluoro-1-oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012831(1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]azepino[3,2,1-h...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50229038(CHEMBL345917)
Affinity DataIC50:  100nMAssay Description:Inhibition of phosphodiesterase 4 from rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50229039(CHEMBL351568)
Affinity DataIC50:  180nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012885(8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acr...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012831(1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]azepino[3,2,1-h...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012883(1-Oxo-1,2-dihydro-6-oxa-10b-aza-aceanthrylene-2-ca...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012835(1-Oxo-1,2-dihydro-6-thia-10b-aza-aceanthrylene-2-c...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012820(4,8-Difluoro-1-oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012873(1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acridine-2-c...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012841(1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]azepino[3,2,1-h...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012827(10H-Phenoxazine | CHEMBL276850 | PHENOXAZINE)
Affinity DataIC50:  320nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012827(10H-Phenoxazine | CHEMBL276850 | PHENOXAZINE)
Affinity DataIC50:  350nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012861(1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acridine-2-c...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012869(1-Oxo-1,2-dihydro-6-thia-10b-aza-aceanthrylene-2-c...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012856(1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]azepino[3,2,1-h...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012858(1-Oxo-1,2-dihydro-6-thia-10b-aza-aceanthrylene-2-c...)
Affinity DataIC50:  480nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  490nMAssay Description:Inhibition of phosphodiesterase 4 from rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012841(1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]azepino[3,2,1-h...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012839(1-Oxo-1,2-dihydro-6-oxa-10b-aza-aceanthrylene-2-ca...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012877(8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acr...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012848(1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]azepino[3,2,1-h...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012873(1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acridine-2-c...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012839(1-Oxo-1,2-dihydro-6-oxa-10b-aza-aceanthrylene-2-ca...)
Affinity DataIC50:  600nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012875(1-Oxo-1,2-dihydro-6-oxa-10b-aza-aceanthrylene-2-ca...)
Affinity DataIC50:  600nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012870(1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acridine-2-c...)
Affinity DataIC50:  700nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012844(8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acr...)
Affinity DataIC50:  700nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012885(8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acr...)
Affinity DataIC50:  700nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012872(1-Oxo-1,2-dihydro-6-thia-10b-aza-aceanthrylene-2-c...)
Affinity DataIC50:  700nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012820(4,8-Difluoro-1-oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de...)
Affinity DataIC50:  700nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012822(1-Oxo-1,2-dihydro-6-oxa-10b-aza-aceanthrylene-2-ca...)
Affinity DataIC50:  700nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012823(1-Oxo-1,2-dihydro-6-oxa-10b-aza-aceanthrylene-2-ca...)
Affinity DataIC50:  700nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012825(1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]azepino[3,2,1-h...)
Affinity DataIC50:  700nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012877(8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acr...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012872(1-Oxo-1,2-dihydro-6-thia-10b-aza-aceanthrylene-2-c...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012854(1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acridine-2-c...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012856(1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]azepino[3,2,1-h...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012863(8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acr...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012865(1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acridine-2-c...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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