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Found 1627 with Last Name = 'mori' and Initial = 'j'
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM84928(CAS_125368 | FK 1052 | NSC_125368)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM84928(CAS_125368 | FK 1052 | NSC_125368)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50001609(8-Benzyloxy-4-[(methyl-phenethyl-carbamoyl)-methyl...)
Affinity DataKi:  0.140nMAssay Description:Antagonistic activity of the compound against LTB4 receptor using guinea pig (GP) spleen cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50454212(CHEBI:64217 | Emonapride | Nemonapride)
Affinity DataKi:  0.160nMAssay Description:Binding affinity to rat Dopamine receptor D2 expressesd in CHO cells was determined using [125 I ] iodosulpride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50454212(CHEBI:64217 | Emonapride | Nemonapride)
Affinity DataKi:  0.160nMAssay Description:Binding affinity of the compound to rat Dopamine receptor D3 expressed in CHO cells was determined using [125 I] iodosulpride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052196(CHEMBL319597 | N-((S)-1-Bicyclo[3.3.1]non-9-yl-pyr...)
Affinity DataKi:  0.240nMAssay Description:Binding affinity of the compound to rat Dopamine receptor D3 expressed in CHO cells was determined using [125 I] iodosulpride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24466(1-(2-hydroxy-2-methylpropyl)-N-{5-[(7-methoxyquino...)
Affinity DataKi:  0.5nM ΔG°:  -52.6kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052194(4-Amino-N-((R)-1-benzyl-pyrrolidin-3-yl)-5-chloro-...)
Affinity DataKi:  0.550nMAssay Description:Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052191(4-Amino-N-((S)-1-benzyl-pyrrolidin-3-yl)-5-chloro-...)
Affinity DataKi:  0.580nMAssay Description:Binding affinity of the compound to rat Dopamine receptor D3 expressed in CHO cells was determined using [125 I] iodosulpride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052196(CHEMBL319597 | N-((S)-1-Bicyclo[3.3.1]non-9-yl-pyr...)
Affinity DataKi:  0.670nMAssay Description:Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50052196(CHEMBL319597 | N-((S)-1-Bicyclo[3.3.1]non-9-yl-pyr...)
Affinity DataKi:  0.810nMAssay Description:Binding affinity to rat Dopamine receptor D2 expressesd in CHO cells was determined using [125 I ] iodosulpride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50052191(4-Amino-N-((S)-1-benzyl-pyrrolidin-3-yl)-5-chloro-...)
Affinity DataKi:  0.980nMAssay Description:Binding affinity to rat Dopamine receptor D2 expressesd in CHO cells was determined using [125 I ] iodosulpride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24459(N-{3-fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl}...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24462(N-{3-fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl}...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24460(N-{3-fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl}...)
Affinity DataKi:  1.02nM ΔG°:  -50.8kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to rat Dopamine receptor D2 expressesd in CHO cells was determined using [125 I ] iodosulpride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052191(4-Amino-N-((S)-1-benzyl-pyrrolidin-3-yl)-5-chloro-...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24463(N-{3-fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl}...)
Affinity DataKi:  1.10nM ΔG°:  -50.6kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24466(1-(2-hydroxy-2-methylpropyl)-N-{5-[(7-methoxyquino...)
Affinity DataKi:  1.10nM ΔG°:  -50.6kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24466(1-(2-hydroxy-2-methylpropyl)-N-{5-[(7-methoxyquino...)
Affinity DataKi:  1.20nM ΔG°:  -50.4kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50052194(4-Amino-N-((R)-1-benzyl-pyrrolidin-3-yl)-5-chloro-...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to rat Dopamine receptor D2 expressesd in CHO cells was determined using [125 I ] iodosulpride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052186(4-Acryloylamino-N-((S)-1-benzyl-pyrrolidin-3-yl)-5...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24464(N-{3-fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl}...)
Affinity DataKi:  1.30nM ΔG°:  -50.2kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052184(5-Chloro-N-((S)-1-cycloheptyl-pyrrolidin-3-yl)-4-(...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity of the compound to rat Dopamine receptor D3 expressed in CHO cells was determined using [125 I] iodosulpride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052195(CHEMBL93198 | N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-c...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052181(CHEMBL92924 | N-((S)-1-Adamantan-2-yl-pyrrolidin-3...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity of the compound to rat Dopamine receptor D3 expressed in CHO cells was determined using [125 I] iodosulpride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052194(4-Amino-N-((R)-1-benzyl-pyrrolidin-3-yl)-5-chloro-...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity of the compound to rat Dopamine receptor D3 expressed in CHO cells was determined using [125 I] iodosulpride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052182(CHEMBL330318 | N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50001609(8-Benzyloxy-4-[(methyl-phenethyl-carbamoyl)-methyl...)
Affinity DataKi:  2nMAssay Description:Antagonistic activity of the compound against monkey neutrophil LTB4 receptor 2 min after an iv dose of 3 mg/kg .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Mus musculus)
Amgen

LigandPNGBDBM24466(1-(2-hydroxy-2-methylpropyl)-N-{5-[(7-methoxyquino...)
Affinity DataKi:  2nM ΔG°:  -49.2kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM24464(N-{3-fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl}...)
Affinity DataKi:  2nM ΔG°:  -49.2kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052199(5-Chloro-N-((S)-1-cyclohexyl-pyrrolidin-3-yl)-4-(c...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052180(CHEMBL328866 | N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  2.10nMAssay Description:Compound was tested for the binding affinity against rat cortical Muscarinic acetylcholine receptor M1 by radioligand [3H]-pirenzepine binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052183(CHEMBL94050 | N-((S)-1-Bicyclo[3.3.1]non-9-yl-pyrr...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity of the compound to rat Dopamine receptor D3 expressed in CHO cells was determined using [125 I] iodosulpride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11123((2S)-1-[(2S)-2-amino-3-[4-(2,4-difluorophenyl)phen...)
Affinity DataKi:  2.20nM ΔG°:  -49.4kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24466(1-(2-hydroxy-2-methylpropyl)-N-{5-[(7-methoxyquino...)
Affinity DataKi:  2.20nM ΔG°:  -48.9kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052184(5-Chloro-N-((S)-1-cycloheptyl-pyrrolidin-3-yl)-4-(...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24465(N-{3-fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl}...)
Affinity DataKi:  2.70nM ΔG°:  -48.4kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052179(CHEMBL93021 | N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-c...)
Affinity DataKi:  3nMAssay Description:Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11121((2S)-1-[(2S)-2-amino-3-[4-(4-fluorophenyl)phenyl]p...)
Affinity DataKi:  3.10nM ΔG°:  -48.6kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052197(5-Chloro-N-((S)-1-cyclohexylmethyl-pyrrolidin-3-yl...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052200(5-Chloro-4-(cyclopropanecarbonyl-amino)-2-methoxy-...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052197(5-Chloro-N-((S)-1-cyclohexylmethyl-pyrrolidin-3-yl...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity of the compound to rat Dopamine receptor D3 expressed in CHO cells was determined using [125 I] iodosulpride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of human cloned CA12 catalytic domain by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052183(CHEMBL94050 | N-((S)-1-Bicyclo[3.3.1]non-9-yl-pyrr...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24466(1-(2-hydroxy-2-methylpropyl)-N-{5-[(7-methoxyquino...)
Affinity DataKi:  4.10nM ΔG°:  -47.4kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052199(5-Chloro-N-((S)-1-cyclohexyl-pyrrolidin-3-yl)-4-(c...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity of the compound to rat Dopamine receptor D3 expressed in CHO cells was determined using [125 I] iodosulpride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50052181(CHEMBL92924 | N-((S)-1-Adamantan-2-yl-pyrrolidin-3...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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