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Found 2799 with Last Name = 'murugesan' and Initial = 'n'
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50091105(4''-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dime...)
Affinity DataKi: >0.000100nMAssay Description:Compound was evaluated for its binding affinity towards rat Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50042235(2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4...)
Affinity DataKi: >0.000100nMAssay Description:Compound was evaluated for its binding affinity towards human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50091105(4''-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dime...)
Affinity DataKi: >0.000100nMAssay Description:Compound was evaluated for its binding affinity towards human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122692(CHEMBL282336 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsu...)
Affinity DataKi:  0.00100nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122693(CHEMBL29346 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsul...)
Affinity DataKi:  0.00400nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122706(2'-(3-Methyl-2-oxo-imidazolidin-1-ylmethyl)-4'-oxa...)
Affinity DataKi:  0.00400nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122686(1-Methyl-1H-indole-2-carboxylic acid [2'-(3,4-dime...)
Affinity DataKi:  0.00500nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122694(2'-(3,3-Dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-4'-o...)
Affinity DataKi:  0.00500nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122715(3,5-Dichloro-N-[2'-(3,4-dimethyl-isoxazol-5-ylsulf...)
Affinity DataKi:  0.00900nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122676(CHEMBL274489 | N-[2'-(4,5-Dimethyl-isoxazol-3-ylsu...)
Affinity DataKi:  0.0100nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122712(CHEMBL440780 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsu...)
Affinity DataKi:  0.0100nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122700(4'-Oxazol-2-yl-2'-(3-trifluoromethyl-pyrazol-1-ylm...)
Affinity DataKi:  0.0200nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122697(2'-[(Methyl-phenyl-amino)-methyl]-4'-oxazol-2-yl-b...)
Affinity DataKi:  0.0200nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122707(CHEMBL281659 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsu...)
Affinity DataKi:  0.0200nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122681(CHEMBL27855 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsul...)
Affinity DataKi:  0.0300nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122698(CHEMBL28863 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsul...)
Affinity DataKi:  0.0400nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122713(CHEMBL282359 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsu...)
Affinity DataKi:  0.0400nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122684(2'-(4,4-Dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-4'-o...)
Affinity DataKi:  0.0450nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122690(CHEMBL28963 | N-Cyclopropyl-N-[2'-(3,4-dimethyl-is...)
Affinity DataKi:  0.0500nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122696(CHEMBL281549 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsu...)
Affinity DataKi:  0.0500nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122703(2'-[(5-Methyl-isoxazol-3-ylamino)-methyl]-4'-oxazo...)
Affinity DataKi:  0.0700nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122711(4'-Oxazol-2-yl-2'-(pyrimidin-4-ylaminomethyl)-biph...)
Affinity DataKi:  0.150nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122704(2'-{[Methyl-(2,2,2-trifluoro-ethyl)-amino]-methyl}...)
Affinity DataKi:  0.150nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122710(CHEMBL284656 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsu...)
Affinity DataKi:  0.200nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50091104(CHEMBL29422 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsul...)
Affinity DataKi:  0.200nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50091104(CHEMBL29422 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsul...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of Human Endothelin A receptor expressed in CHO Cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122678(2'-Isobutoxymethyl-4'-oxazol-2-yl-biphenyl-2-sulfo...)
Affinity DataKi:  0.200nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122699(2'-Imidazol-1-ylmethyl-4'-oxazol-2-yl-biphenyl-2-s...)
Affinity DataKi:  0.300nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122680(4'-Oxazol-2-yl-2'-pyrazol-1-ylmethyl-biphenyl-2-su...)
Affinity DataKi:  0.300nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122689(2'-(3,3-Dimethyl-2-oxo-piperidin-1-ylmethyl)-4'-ox...)
Affinity DataKi:  0.390nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122679(CHEMBL29775 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsul...)
Affinity DataKi:  0.400nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122705(2-Cyclohexyl-N-[2'-(3,4-dimethyl-isoxazol-5-ylsulf...)
Affinity DataKi:  0.440nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50091101(4'-Oxazol-4-yl-biphenyl-2-sulfonic acid (3,4-dimet...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of Human Endothelin A receptor expressed in CHO Cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122708(2'-Isopropoxymethyl-4'-oxazol-2-yl-biphenyl-2-sulf...)
Affinity DataKi:  0.600nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122702(CHEMBL30215 | N-tert-Butyl-2-[2'-(3,4-dimethyl-iso...)
Affinity DataKi:  0.600nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122695(CHEMBL29710 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsul...)
Affinity DataKi:  0.600nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A/B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125339(3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-2-meth...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards Angiotensin II receptor, type 1 in rat aortic smooth muscle cells using 0.2 nM [125I]-labeled Sar-Ile-angiotensin IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  0.730nMAssay Description:Displacement of [3H]BMS-725519 from human CB1 receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122687(4'-Oxazol-2-yl-2'-oxazol-2-ylmethyl-biphenyl-2-sul...)
Affinity DataKi:  0.75nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122677(4'-Oxazol-2-yl-2'-[(2,2,2-trifluoro-ethylamino)-me...)
Affinity DataKi:  0.800nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50042235(2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4...)
Affinity DataKi:  0.800nMAssay Description:Compound was evaluated for its binding affinity towards rat Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109666(4'-Pyrimidin-2-yl-biphenyl-2-sulfonic acid (3,4-di...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to CHO cells stably expressing human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125343(2'-(3,3-Dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-4'-(...)
Affinity DataKi:  1nMAssay Description:Binding affinity towards human ETA receptor expressed in CHO-K1 cells in the presence of 0.05 nM [125I]-labeled endothelin 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122709(2-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxaz...)
Affinity DataKi:  1nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50122683(4'-Oxazol-2-yl-2'-phenoxymethyl-biphenyl-2-sulfoni...)
Affinity DataKi:  1nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50042235(2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4...)
Affinity DataKi:  1.10nMAssay Description:Compound was evaluated for its binding affinity towards human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A/B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125362(3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-2-ethy...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity towards Angiotensin II receptor, type 1 in rat aortic smooth muscle cells using 0.2 nM [125I]-labeled Sar-Ile-angiotensin IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011322(CHEMBL3260745)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50091105(4''-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dime...)
Affinity DataKi:  1.40nMAssay Description:Compound was evaluated for its binding affinity towards human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50091105(4''-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dime...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of Human Endothelin A receptor expressed in CHO Cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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