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Found 252 with Last Name = 'nelson' and Initial = 'sl'
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM85093(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200028(2-methoxy-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipy...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150141(2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataKi:  1.5nMAssay Description:In vitro binding affinity tested on HEK293 cells co-transfected with human D4.4 receptor using [3H]spiperone as a radioligand in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145073(5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity towards human D4.4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [125I]7-OH-PIPAT from human D2L receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179735(4-(3,4-dichlorobenzylthio)-2-aminobutanoic acid | ...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150143(2-[4-(2,5-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataKi:  3.80nMAssay Description:In vitro binding affinity tested on HEK293 cells co-transfected with human D4.4 receptor using [3H]spiperone as a radioligand in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145078(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...)
Affinity DataKi:  4.30nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179703(4-(4-chlorobenzylthio)-2-aminobutanoic acid | CHEM...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179700(4-(4-bromobenzylthio)-2-aminobutanoic acid | CHEMB...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179710(4-(2,3-dichlorobenzylthio)-2-aminobutanoic acid | ...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179732(2-amino-4-(2-methyl-benzylsulfanyl)-butyric acid |...)
Affinity DataKi:  7.60nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200037(2-(3',4',-5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145081(2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-be...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145081(2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-be...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145076(2-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-be...)
Affinity DataKi:  9.60nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145076(2-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-be...)
Affinity DataKi:  9.60nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145084(2-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-be...)
Affinity DataKi:  14.8nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145084(2-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-be...)
Affinity DataKi:  14.8nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200029(6-(4-((1H-benzo[d]imidazol-2-yl)methyl)piperazin-1...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179701(4-(2,3,4-trichlorobenzylthio)-2-aminobutanoic acid...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179689(4-(3,5-dichlorobenzylthio)-2-aminobutanoic acid | ...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179707(4-(3-fluorobenzylthio)-2-aminobutanoic acid | CHEM...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179711(4-(2-bromobenzylthio)-2-aminobutanoic acid | CHEMB...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145072(2-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...)
Affinity DataKi:  20.4nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179736(4-(2,5-dichlorobenzylthio)-2-aminobutanoic acid | ...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179722(4-(3-chlorobenzylthio)-2-aminobutanoic acid | CHEM...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145083(2-[4-(3-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...)
Affinity DataKi:  26.5nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200028(2-methoxy-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipy...)
Affinity DataKi:  27nMAssay Description:Displacement of [125I]7-OH-PIPAT from human D2L receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179713((S)-2-amino-4-(benzylthio)butanoic acid | CHEMBL38...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179727(4-(3-bromobenzylthio)-2-aminobutanoic acid | CHEMB...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179715(4-(2-(trifluoromethyl)benzylthio)-2-aminobutanoic ...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200043(3-methyl-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipyr...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145079(2-(4-Phenyl-piperazin-1-ylmethyl)-1H-benzoimidazol...)
Affinity DataKi:  33nMAssay Description:Binding affinity tested against D4.2 receptor in Chinese hamster ovary cell line (CHO cells) using [3H]spiperone as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179690(4-(3-nitrobenzylthio)-2-aminobutanoic acid | CHEMB...)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179696(2-amino-2-(3-bromophenyl)acetic acid | CHEMBL38237...)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145079(2-(4-Phenyl-piperazin-1-ylmethyl)-1H-benzoimidazol...)
Affinity DataKi:  52nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179731(2-amino-2-(3-chlorophenyl)acetic acid | CHEMBL2046...)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179712((S)-2-amino-2-cyclohexylacetic acid | CHEMBL382372...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179718(CHEMBL380671 | rac-2-amino-5-cyclohexylpentanoic a...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179737(4-(3,4-dimethylbenzylthio)-2-aminobutanoic acid | ...)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179698(4-(4-tert-butylbenzylthio)-2-aminobutanoic acid | ...)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145080(2-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-be...)
Affinity DataKi:  79.6nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179725((S)-2-amino-3-cyclohexylpropanoic acid | 2-AMINO-3...)
Affinity DataKi:  90nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179717(2-amino-2-(2,3-difluorophenyl)acetic acid | CHEMBL...)
Affinity DataKi:  96nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179728(4-(2,4-bis(trifluoromethyl)benzylthio)-2-aminobuta...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179693((S)-2-amino-4-(ethylthio)butanoic acid | 2-AMINO-4...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50179697((S)-2-amino-3-(benzylthio)propanoic acid | CHEMBL2...)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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