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Found 57 with Last Name = 'niizuma' and Initial = 'h'
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111903((S)-1-[(S)-2-{2-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataKi:  0.000540nMAssay Description:Binding affinity of the compound against Opioid receptor mu 1 using [3H]-DAMGO in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111905((S)-4-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataKi:  0.00105nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 using [3H]-DT in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125999((R)-2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...)
Affinity DataKi:  0.00205nMAssay Description:Ability of the compound to displace [3H]-DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataKi:  0.00260nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 using [3H]-DT in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50126000((R)-2-[(S)-2-Amino-3-(2,6-dimethyl-phenyl)-propion...)
Affinity DataKi:  0.0216nMAssay Description:Ability of the compound to displace [3H]-DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50126003((R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataKi:  0.0350nMAssay Description:Ability of the compound to displace [3H]-DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125997((R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataKi:  0.0618nMAssay Description:Ability of the compound to displace [3H]-DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125996((R)-2-[(S)-2-Amino-3-(2,6-dimethyl-phenyl)-propion...)
Affinity DataKi:  0.0623nMAssay Description:Ability of the compound to displace [3H]-DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50059841((S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataKi:  0.0920nMAssay Description:Binding affinity of the compound against Opioid receptor mu 1 using [3H]-DAMGO in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125998((R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataKi:  0.172nMAssay Description:Ability of the compound to displace [3H]-DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125999((R)-2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...)
Affinity DataKi:  1.10nMAssay Description:Ability of the compound to displace [3H]-deltorphin II from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111906((S)-1-[(S)-2-{2-[(R)-2-{(R)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity of the compound against Opioid receptor mu 1 using [3H]-DAMGO in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50126001((R)-2-((S)-2-Amino-3-phenyl-propionylamino)-5-guan...)
Affinity DataKi:  7.20nMAssay Description:Ability of the compound to displace [3H]-DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50126002((R)-2-[(R)-2-Amino-3-(2,6-dimethyl-phenyl)-propion...)
Affinity DataKi:  7.60nMAssay Description:Ability of the compound to displace [3H]-DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111903((S)-1-[(S)-2-{2-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataKi:  46nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 using [3H]-DT in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111904((S)-4-[(R)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataKi:  111nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 using [3H]-DT in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50059841((S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataKi:  192nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 using [3H]-DT in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataKi:  314nMAssay Description:Binding affinity of the compound against Opioid receptor mu 1 using [3H]-DAMGO in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125998((R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataKi:  482nMAssay Description:Ability of the compound to displace [3H]-deltorphin II from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50126003((R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataKi:  544nMAssay Description:Ability of the compound to displace [3H]-deltorphin II from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111905((S)-4-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity of the compound against Opioid receptor mu 1 using [3H]-DAMGO in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50126000((R)-2-[(S)-2-Amino-3-(2,6-dimethyl-phenyl)-propion...)
Affinity DataKi:  1.69E+3nMAssay Description:Ability of the compound to displace [3H]-deltorphin II from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111904((S)-4-[(R)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataKi:  1.96E+3nMAssay Description:Binding affinity of the compound against Opioid receptor mu 1 using [3H]-DAMGO in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125996((R)-2-[(S)-2-Amino-3-(2,6-dimethyl-phenyl)-propion...)
Affinity DataKi:  2.57E+3nMAssay Description:Ability of the compound to displace [3H]-deltorphin II from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50126001((R)-2-((S)-2-Amino-3-phenyl-propionylamino)-5-guan...)
Affinity DataKi: >2.82E+3nMAssay Description:Ability of the compound to displace [3H]-deltorphin II from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50126002((R)-2-[(R)-2-Amino-3-(2,6-dimethyl-phenyl)-propion...)
Affinity DataKi: >2.82E+3nMAssay Description:Ability of the compound to displace [3H]-deltorphin II from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125997((R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataKi: >2.82E+3nMAssay Description:Ability of the compound to displace [3H]-deltorphin II from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111906((S)-1-[(S)-2-{2-[(R)-2-{(R)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataKi:  3.30E+3nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 using [3H]-DT in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111905((S)-4-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.0220nMAssay Description:In vitro biological activity by electrically induced smooth muscle contractions in mouse vas deferens (Opioid receptor delta 1); inhibitory concentra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125999((R)-2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...)
Affinity DataIC50:  0.0340nMAssay Description:Ability of the compound to inhibit electrically induced contractions of guinea pig ileum having mu opioid receptors tested in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50292220(1-[2-[(S)-(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-ph...)
Affinity DataIC50:  0.0710nMAssay Description:Inhibitory concentration in guinea-pig ileum assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125999((R)-2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...)
Affinity DataIC50:  0.398nMAssay Description:Ability of the compound to inhibit electrically induced contractions of mouse vas deferens having delta opioid receptors tested in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.582nMAssay Description:In vitro biological activity by electrically induced smooth muscle contractions in mouse vas deferens (Opioid receptor delta 1); inhibitory concentra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111903((S)-1-[(S)-2-{2-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataIC50:  1.20nMAssay Description:In vitro biological activity by electrically induced smooth muscle contractions in guinea pig ileum (Opioid receptor mu 1); inhibitory concentration ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50126003((R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataIC50:  1.70nMAssay Description:Ability of the compound to inhibit electrically induced contractions of guinea pig ileum having mu opioid receptors tested in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50126000((R)-2-[(S)-2-Amino-3-(2,6-dimethyl-phenyl)-propion...)
Affinity DataIC50:  2.80nMAssay Description:Ability of the compound to inhibit electrically induced contractions of guinea pig ileum having mu opioid receptors tested in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50059841((S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataIC50:  3.70nMAssay Description:In vitro biological activity by electrically induced smooth muscle contractions in guinea pig ileum (Opioid receptor mu 1); inhibitory concentration ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111903((S)-1-[(S)-2-{2-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataIC50:  4.60nMAssay Description:In vitro biological activity by electrically induced smooth muscle contractions in mouse vas deferens (Opioid receptor delta 1); inhibitory concentra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125998((R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataIC50:  5.30nMAssay Description:Ability of the compound to inhibit electrically induced contractions of guinea pig ileum having mu opioid receptors tested in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125996((R)-2-[(S)-2-Amino-3-(2,6-dimethyl-phenyl)-propion...)
Affinity DataIC50:  9.90nMAssay Description:Ability of the compound to inhibit electrically induced contractions of guinea pig ileum having mu opioid receptors tested in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125997((R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataIC50:  20nMAssay Description:Ability of the compound to inhibit electrically induced contractions of guinea pig ileum having mu opioid receptors tested in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50126003((R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataIC50:  28nMAssay Description:Ability of the compound to inhibit electrically induced contractions of mouse vas deferens having delta opioid receptors tested in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50059841((S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataIC50:  34nMAssay Description:In vitro biological activity by electrically induced smooth muscle contractions in mouse vas deferens (Opioid receptor delta 1); inhibitory concentra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111906((S)-1-[(S)-2-{2-[(R)-2-{(R)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataIC50:  44nMAssay Description:In vitro biological activity by electrically induced smooth muscle contractions in guinea pig ileum (Opioid receptor mu 1); inhibitory concentration ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50126000((R)-2-[(S)-2-Amino-3-(2,6-dimethyl-phenyl)-propion...)
Affinity DataIC50:  50nMAssay Description:Ability of the compound to inhibit electrically induced contractions of mouse vas deferens having delta opioid receptors tested in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125998((R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataIC50:  116nMAssay Description:Ability of the compound to inhibit electrically induced contractions of mouse vas deferens having delta opioid receptors tested in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111904((S)-4-[(R)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  145nMAssay Description:In vitro biological activity by electrically induced smooth muscle contractions in mouse vas deferens (Opioid receptor delta 1); inhibitory concentra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125996((R)-2-[(S)-2-Amino-3-(2,6-dimethyl-phenyl)-propion...)
Affinity DataIC50:  188nMAssay Description:Ability of the compound to inhibit electrically induced contractions of mouse vas deferens having delta opioid receptors tested in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125997((R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataIC50:  305nMAssay Description:Ability of the compound to inhibit electrically induced contractions of mouse vas deferens having delta opioid receptors tested in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50126002((R)-2-[(R)-2-Amino-3-(2,6-dimethyl-phenyl)-propion...)
Affinity DataIC50:  320nMAssay Description:Ability of the compound to inhibit electrically induced contractions of guinea pig ileum having mu opioid receptors tested in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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