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Found 1448 with Last Name = 'ortega muñoz' and Initial = 'a'
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254546(US10214477, Example 3 | US9469597, 1 | US9670136, ...)
Affinity DataKi:  50nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254603(US10214477, Example 5 | US9469597, 4 | US9670136, ...)
Affinity DataKi:  50nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM50155773(CHEMBL3781751 | US9469597, 5)
Affinity DataKi:  50nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254553(US9469597, 12 | US9670136, 12 4-(((trans)-2-(6-(3-...)
Affinity DataKi:  50nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254556(US10214477, Example 15 | US9469597, 15 | US9670136...)
Affinity DataKi:  50nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM256457(US9487512, 1)
Affinity DataKi:  50nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM256459(US10329256, Example 3 | US9487512, 3 | US9944601, ...)
Affinity DataKi:  50nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM256460(US9487512, 4)
Affinity DataKi:  50nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50142189(CHEMBL3759239 | US10329256, Example 5 | US9487512,...)
Affinity DataKi:  50nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM256461(US10329256, Example 6 | US9487512, 6 | US9944601, ...)
Affinity DataKi:  50nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179729(US9676701, 48 3-(5-((trans)-2-amninocyclopropyl)py...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM261742(US9708309, 2)
Affinity DataKi:  50nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254546(US10214477, Example 3 | US9469597, 1 | US9670136, ...)
Affinity DataKi:  50nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254603(US10214477, Example 5 | US9469597, 4 | US9670136, ...)
Affinity DataKi:  50nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254603(US10214477, Example 5 | US9469597, 4 | US9670136, ...)
Affinity DataKi:  50nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM356626(US10214477, Example 12)
Affinity DataKi:  50nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254556(US10214477, Example 15 | US9469597, 15 | US9670136...)
Affinity DataKi:  50nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM261741(US10233178, Example 1 | US9708309, 1)
Affinity DataKi:  50nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM369812(5-(((trans)-2-(4-(benzyloxy)phenyl)cyclopropylamin...)
Affinity DataKi:  50nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179652(US9676701, 23 5-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179653(US9676701, 24 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179654(US9676701, 25 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179670(US9676701, 29 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179672(US9676701, 31 (trans)-2-(6-(5-chlorothiophen-2-yl)...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179724(US9676701, 46 5-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM261741(US10233178, Example 1 | US9708309, 1)
Affinity DataKi:  50nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179446(US9676701, 4 4′-((trans)-2-aminocyclopropyl)...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179461(US9676701, 9 (trans)-2-(6-(4-(trifluoromethyl)phen...)
Affinity DataKi:  50nMpH: 7.5Assay Description:Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179641(US9676701, 13 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179646(US9676701, 17 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179649(US9676701, 20 2-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179646(US9676701, 17 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179865(US9676701, 99 N-(3-(5-((trans)-2-aminocyclopropyl)...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179905(US9676701, 100 N-(3-(5-((trans)-2-aminocyclopropyl...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179906(US9676701, 101 N-(3-(5-((trans)-2-aminocyclopropyl...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179933(US9676701, 102 N-(3-(5-((trans)-2-aminocyclopropyl...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179973(US9676701, 113 3-(5-((trans)-2-aminocyclopropyl)th...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179976(US9676701, 116 3-(5-((trans)-2-aminocyclopropyl)th...)
Affinity DataKi:  50nMpH: 7.5Assay Description:Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179976(US9676701, 116 3-(5-((trans)-2-aminocyclopropyl)th...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179984(US9676701, 124 N-(3-(5-((trans)-2-aminocyclopropyl...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM182862(US9670136, 1 N1-((trans)-2-phenylcyclopropyl)cyclo...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254546(US10214477, Example 3 | US9469597, 1 | US9670136, ...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254546(US10214477, Example 3 | US9469597, 1 | US9670136, ...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254553(US9469597, 12 | US9670136, 12 4-(((trans)-2-(6-(3-...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254556(US10214477, Example 15 | US9469597, 15 | US9670136...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM50158875(CHEMBL3787372 | US9676701, 69 N-(4′-((trans)...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179835(US9676701, 70 N-(4′-((trans)-2-aminocyclopro...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179840(US9676701, 75 N-(4′-((trans)-2-aminocyclopro...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179854(US9676701, 88 N-(4′-((trans)-2-aminocyclopro...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179855(US9676701, 89 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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