Compile Data Set for Download or QSAR
maximum 50k data
Found 104 with Last Name = 'palzkill' and Initial = 't'
TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College Of Medicine

LigandPNGBDBM484193(CDD-1714)
Affinity DataKi:  24nMAssay Description:To determine the Ki values of active compounds, 25 nM Mpro was mixed with increasing concentrations of compounds (from 4 nM to 4,000 nM with twofold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College Of Medicine

LigandPNGBDBM484197(CDD-1976 | WO2023004291, Compound CDD-1976)
Affinity DataKi:  42nMAssay Description:To determine the Ki values of active compounds, 25 nM Mpro was mixed with increasing concentrations of compounds (from 4 nM to 4,000 nM with twofold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College Of Medicine

LigandPNGBDBM484196(CDD-1713 | WO2023004291, Compound CDD-1713)
Affinity DataKi:  65nMAssay Description:To determine the Ki values of active compounds, 25 nM Mpro was mixed with increasing concentrations of compounds (from 4 nM to 4,000 nM with twofold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College Of Medicine

LigandPNGBDBM484198(CDD-1777)
Affinity DataKi:  2.40E+3nMAssay Description:To determine the Ki values of active compounds, 25 nM Mpro was mixed with increasing concentrations of compounds (from 4 nM to 4,000 nM with twofold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of recombinant Pseudomonas aeruginosa MBL IMP-1 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
TargetBeta-lactamase(Pseudomonas aeruginosa)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50421220(CHEMBL2087628)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of recombinant Pseudomonas aeruginosa MBL IMP-1 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Bacillus anthracis)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50421214(CHEMBL2087633)
Affinity DataKi:  5.10E+3nMAssay Description:Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Bacillus anthracis)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataKi:  1.79E+4nMAssay Description:Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140666((2S,5R,6S)-6-Mercaptomethyl-3,3-dimethyl-4,4,7-tri...)
Affinity DataIC50:  100nMAssay Description:Inhibition of class B (BCII) metallo-beta-lactamase representative enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140673((2S,5R,6S)-6-Mercaptomethyl-3,3-dimethyl-7-oxo-4-t...)
Affinity DataIC50:  100nMAssay Description:Beta-Lactamase inhibitory activity against representativeclass C (P99) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)
Affinity DataIC50:  122nMAssay Description:Beta-Lactamase inhibitory activity against representative class A (TEM-1) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacillus cereus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140668((2S,5R,6R)-6-Mercaptomethyl-3,3-dimethyl-4,4,7-tri...)
Affinity DataIC50:  300nMAssay Description:Beta-Lactamase Inhibition of metallo-beta-lactamase representative class B (L1) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140668((2S,5R,6R)-6-Mercaptomethyl-3,3-dimethyl-4,4,7-tri...)
Affinity DataIC50:  300nMAssay Description:Beta-Lactamase Inhibition of metallo-beta-lactamase representative class B (L1) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50076678((2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trio...)
Affinity DataIC50:  650nMAssay Description:Beta-Lactamase inhibitory activity against representative class A (TEM-1) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140669((2S,5R,6S)-6-Mercapto-3,3-dimethyl-4,4,7-trioxo-4l...)
Affinity DataIC50:  1.40E+3nMAssay Description:Beta-Lactamase inhibitory activity against representativeclass C (P99) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacillus cereus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140666((2S,5R,6S)-6-Mercaptomethyl-3,3-dimethyl-4,4,7-tri...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of class B (BCII) metallo-beta-lactamase representative enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College Of Medicine

LigandPNGBDBM484197(CDD-1976 | WO2023004291, Compound CDD-1976)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of SARS-CoV-2 replication in VERO E6 and HEK hACE2 cells was measured using an xCELLigence RTCA HT Analyzer (Agilent Technologies), tracki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140667((2S,5R,6R)-6-Mercaptomethyl-3,3-dimethyl-7-oxo-4-t...)
Affinity DataIC50:  3.75E+3nMAssay Description:Beta-Lactamase inhibitory activity against representativeclass C (P99) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50076678((2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trio...)
Affinity DataIC50:  3.90E+3nMAssay Description:Beta-Lactamase inhibitory activity against representativeclass C (P99) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Bacillus anthracis)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50421214(CHEMBL2087633)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant Pseudomonas aeruginosa MBL IMP-1 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College Of Medicine

LigandPNGBDBM484196(CDD-1713 | WO2023004291, Compound CDD-1713)
Affinity DataIC50:  5.19E+3nMAssay Description:Inhibition of SARS-CoV-2 replication in VERO E6 and HEK hACE2 cells was measured using an xCELLigence RTCA HT Analyzer (Agilent Technologies), tracki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBeta-lactamase(Pseudomonas aeruginosa)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50421220(CHEMBL2087628)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of recombinant Pseudomonas aeruginosa MBL IMP-1 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140666((2S,5R,6S)-6-Mercaptomethyl-3,3-dimethyl-4,4,7-tri...)
Affinity DataIC50:  6.80E+3nMAssay Description:Beta-Lactamase inhibitory activity against representative class A (TEM-1) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140668((2S,5R,6R)-6-Mercaptomethyl-3,3-dimethyl-4,4,7-tri...)
Affinity DataIC50:  7.50E+3nMAssay Description:Beta-Lactamase inhibitory activity against representativeclass C (P99) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140669((2S,5R,6S)-6-Mercapto-3,3-dimethyl-4,4,7-trioxo-4l...)
Affinity DataIC50:  7.60E+3nMAssay Description:Beta-Lactamase Inhibition of metallo-beta-lactamase representative class B (L1) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM26116(CHEMBL284104 | Dipicolinate | pyridine carboxylate...)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of class B (BCII) metallo-beta-lactamase representative enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140670((2S,5R,6S)-6-Mercapto-3,3-dimethyl-7-oxo-4-thia-1-...)
Affinity DataIC50:  7.90E+3nMAssay Description:Beta-Lactamase inhibitory activity against representativeclass C (P99) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50076672((2S,5R,6S)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trio...)
Affinity DataIC50:  1.00E+4nMAssay Description:Beta-Lactamase inhibitory activity against representativeclass C (P99) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140666((2S,5R,6S)-6-Mercaptomethyl-3,3-dimethyl-4,4,7-tri...)
Affinity DataIC50:  1.05E+4nMAssay Description:Beta-Lactamase inhibitory activity against representativeclass C (P99) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140667((2S,5R,6R)-6-Mercaptomethyl-3,3-dimethyl-7-oxo-4-t...)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibition of class B (BCII) metallo-beta-lactamase representative enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacillus cereus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140667((2S,5R,6R)-6-Mercaptomethyl-3,3-dimethyl-7-oxo-4-t...)
Affinity DataIC50:  1.09E+4nMAssay Description:Beta-Lactamase Inhibition of metallo-beta-lactamase representative class B (L1) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50076672((2S,5R,6S)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trio...)
Affinity DataIC50:  1.46E+4nMAssay Description:Beta-Lactamase inhibitory activity against representative class A (TEM-1) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacillus cereus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140670((2S,5R,6S)-6-Mercapto-3,3-dimethyl-7-oxo-4-thia-1-...)
Affinity DataIC50:  1.72E+4nMAssay Description:Inhibition of class B (BCII) metallo-beta-lactamase representative enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacillus cereus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM26116(CHEMBL284104 | Dipicolinate | pyridine carboxylate...)
Affinity DataIC50:  2.18E+4nMAssay Description:Inhibition of class B (BCII) metallo-beta-lactamase representative enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Bacillus anthracis)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50:  2.58E+4nMAssay Description:Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
TargetBeta-lactamase(Pseudomonas aeruginosa)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50330325(2,2',2'',2'''-(ethane-1,2-diylbis(azanetriyl))tetr...)
Affinity DataIC50:  2.79E+4nMAssay Description:Inhibition of recombinant Pseudomonas aeruginosa MBL IMP-1 using nitrocefin as substrate after 12 hrs by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacillus cereus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140673((2S,5R,6S)-6-Mercaptomethyl-3,3-dimethyl-7-oxo-4-t...)
Affinity DataIC50:  3.21E+4nMAssay Description:Beta-Lactamase Inhibition of metallo-beta-lactamase representative class B (L1) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140673((2S,5R,6S)-6-Mercaptomethyl-3,3-dimethyl-7-oxo-4-t...)
Affinity DataIC50:  3.21E+4nMAssay Description:Beta-Lactamase Inhibition of metallo-beta-lactamase representative class B (L1) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50421221(CHEMBL1722922)
Affinity DataIC50:  3.47E+4nMAssay Description:Inhibition of recombinant Pseudomonas aeruginosa MBL IMP-1 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140670((2S,5R,6S)-6-Mercapto-3,3-dimethyl-7-oxo-4-thia-1-...)
Affinity DataIC50:  3.69E+4nMAssay Description:Inhibition of class B (BCII) metallo-beta-lactamase representative enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacillus cereus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140665((2S,5R,6R)-6-Mercapto-3,3-dimethyl-7-oxo-4-thia-1-...)
Affinity DataIC50:  4.14E+4nMAssay Description:Beta-Lactamase Inhibition of metallo-beta-lactamase representative class B (L1) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140665((2S,5R,6R)-6-Mercapto-3,3-dimethyl-7-oxo-4-thia-1-...)
Affinity DataIC50:  4.14E+4nMAssay Description:Beta-Lactamase Inhibition of metallo-beta-lactamase representative class B (L1) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140665((2S,5R,6R)-6-Mercapto-3,3-dimethyl-7-oxo-4-thia-1-...)
Affinity DataIC50:  4.23E+4nMAssay Description:Beta-Lactamase inhibitory activity against representativeclass C (P99) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140668((2S,5R,6R)-6-Mercaptomethyl-3,3-dimethyl-4,4,7-tri...)
Affinity DataIC50:  5.17E+4nMAssay Description:Beta-Lactamase inhibitory activity against representative class A (TEM-1) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)
Affinity DataIC50:  5.32E+4nMAssay Description:Beta-Lactamase inhibitory activity against representativeclass C (P99) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140669((2S,5R,6S)-6-Mercapto-3,3-dimethyl-4,4,7-trioxo-4l...)
Affinity DataIC50:  6.92E+4nMAssay Description:Beta-Lactamase inhibitory activity against representative class A (TEM-1) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50076678((2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trio...)
Affinity DataIC50:  7.23E+4nMAssay Description:Inhibition of class B (BCII) metallo-beta-lactamase representative enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Bacillus anthracis)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50421216(CHEMBL2087635)
Affinity DataIC50:  7.41E+4nMAssay Description:Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50421214(CHEMBL2087633)
Affinity DataIC50:  7.70E+4nMAssay Description:Inhibition of recombinant Pseudomonas aeruginosa MBL IMP-1 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 104 total ) | Next | Last >>
Jump to: