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Found 1234 with Last Name = 'parker' and Initial = 'em'
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185364(CHEMBL2371908 | CHEMBL415187 | Sub[-Tyr-Arg-Leu-Ar...)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [125I]hPP from human NPY4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM50409214(CHEMBL2110365 | GR-231118)
Affinity DataKi:  0.0700nMAssay Description:Affinity for cloned Y1 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50099198(CHEMBL429531 | Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly...)
Affinity DataKi:  0.0800nMAssay Description:Affinity for cloned Y4 receptor using [125I]-PP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM50099198(CHEMBL429531 | Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly...)
Affinity DataKi:  0.230nMAssay Description:Affinity for cloned Y2 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50409214(CHEMBL2110365 | GR-231118)
Affinity DataKi:  0.260nMAssay Description:Affinity for cloned Y4 receptor using [125I]-PP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM50099197(CHEMBL411117 | Ile-Glu-Pro-Dpr-Tyr-Arg-Leu-Arg-Tyr...)
Affinity DataKi:  0.270nMAssay Description:Affinity for cloned Y1 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373621(CHEMBL403414)
Affinity DataKi:  0.400nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM50099200(CHEMBL410166 | Ile-Glu-Pro-Dpr-Tyr-Arg-Leu-Arg-(CH...)
Affinity DataKi:  0.460nMAssay Description:Affinity for cloned Y1 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM50099198(CHEMBL429531 | Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly...)
Affinity DataKi:  0.520nMAssay Description:Affinity for cloned Y1 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299343((2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulf...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]Arg8-vasopressin from human vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373623(CHEMBL404461)
Affinity DataKi:  0.75nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392835(CHEMBL2151181)
Affinity DataKi: <1nMAssay Description:Inhibition of human recombinant BACE2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(RAT)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299343((2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulf...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Arg8-vasopressin from rat vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50596254(CHEMBL5198665)
Affinity DataKi:  1nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50596252(CHEMBL5190011)
Affinity DataKi:  1nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50398688(CHEMBL2178715)
Affinity DataKi:  1nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50398683(CHEMBL2178147)
Affinity DataKi:  1nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373639(CHEMBL428423)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373624(CHEMBL255353)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50164512(CHEMBL3800286)
Affinity DataKi:  1.40nMAssay Description:Inhibition of recombinant human BACE1 preincubated for 30 mins followed QSY7EISEVNLDAEFC-Eu-amide substrate addition measured after 90 mins by FRET a...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108680(CHEMBL3596517)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373625(CHEMBL403918)
Affinity DataKi:  1.5nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50392835(CHEMBL2151181)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373626(CHEMBL257940)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50398684(CHEMBL2178146)
Affinity DataKi:  2nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185366(CHEMBL2371911 | CHEMBL436499 | Sub[-Trp-Arg-Nva-Ar...)
Affinity DataKi:  2nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373622(CHEMBL255147)
Affinity DataKi:  2nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50596253(CHEMBL5203401)
Affinity DataKi:  2nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50596248(CHEMBL5194897)
Affinity DataKi:  2nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50580216(MK-8931 | SCH 900931 | SCH-900931 | SCH900931 | VE...)
Affinity DataKi:  2nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50398678(CHEMBL2178152)
Affinity DataKi:  2nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185366(CHEMBL2371911 | CHEMBL436499 | Sub[-Trp-Arg-Nva-Ar...)
Affinity DataKi:  2nMAssay Description:Inhibition of [3H]-FPP incorporation into biotin-linked K-ras decapeptide (CVIM) by bovine farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin E(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50271627(CHEMBL507651 | N'-[(1S,2S)-2-[(4S)-1-benzyl-5-oxoi...)
Affinity DataKi:  2nMAssay Description:Inhibition of cathepsin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50099198(CHEMBL429531 | Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly...)
Affinity DataKi:  2.21nMAssay Description:Affinity for cloned Y5 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM50099201(CHEMBL413455 | Ile-Asn-Pro-Cys-Tyr-Arg-Leu-Arg-(CH...)
Affinity DataKi:  2.30nMAssay Description:Affinity for cloned Y1 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373622(CHEMBL255147)
Affinity DataKi:  2.40nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373649(CHEMBL257022)
Affinity DataKi:  2.60nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM50109179(4-[3-(3-{3-[4-(3-Hydroxy-phenyl)-piperidin-1-yl]-p...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373655(CHEMBL257707)
Affinity DataKi:  2.80nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50596255(CHEMBL5195553)
Affinity DataKi:  3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM209918(US9273042, 7 | US9556135, 17)
Affinity DataKi:  3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50398685(CHEMBL2178145)
Affinity DataKi:  3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50398690(CHEMBL2178712)
Affinity DataKi:  3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50596249(CHEMBL5170892)
Affinity DataKi:  3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50596246(CHEMBL5203915)
Affinity DataKi:  3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50596250(CHEMBL5204704)
Affinity DataKi:  3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 5B(RAT)
University Of Heidelberg Zmbh

Curated by PDSP Ki Database
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataKi:  3.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373656(CHEMBL428953)
Affinity DataKi:  3.20nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373653(CHEMBL429679)
Affinity DataKi:  3.20nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM50109122(4-[3-(3-{3-[4-(3-Methoxy-phenyl)-piperidin-1-yl]-p...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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