Affinity DataKi: 0.0500nMAssay Description:Displacement of [125I]hPP from human NPY4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
Affinity DataKi: 0.0700nMAssay Description:Affinity for cloned Y1 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Affinity for cloned Y4 receptor using [125I]-PP as radioligandMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Affinity for cloned Y2 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Affinity for cloned Y4 receptor using [125I]-PP as radioligandMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Affinity for cloned Y1 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
Affinity DataKi: 0.460nMAssay Description:Affinity for cloned Y1 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
Affinity DataKi: 0.520nMAssay Description:Affinity for cloned Y1 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]Arg8-vasopressin from human vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 0.75nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition of human recombinant BACE2 by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]Arg8-vasopressin from rat vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of recombinant human BACE1 preincubated for 30 mins followed QSY7EISEVNLDAEFC-Eu-amide substrate addition measured after 90 mins by FRET a...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of human adenosine A2A receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of [3H]-FPP incorporation into biotin-linked K-ras decapeptide (CVIM) by bovine farnesyltransferaseMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of cathepsin EMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 2.21nMAssay Description:Affinity for cloned Y5 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Affinity for cloned Y1 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
University Of Cincinnati And Va Medical Centers
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair