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Found 57 with Last Name = 'parmar' and Initial = 'b'
TargetCoagulation factor X(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392592(CHEMBL2153381)
Affinity DataKi:  1.10nMAssay Description:Inhibition of F10a assessed as S-2765 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392589(CHEMBL2153377)
Affinity DataKi:  1.5nMAssay Description:Inhibition of F10a assessed as S-2765 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392589(CHEMBL2153377)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of activated protein C assessed as S-2366 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392592(CHEMBL2153381)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of activated protein C assessed as S-2366 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392589(CHEMBL2153377)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of thrombin assessed as S-2238 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392592(CHEMBL2153381)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of thrombin assessed as S-2238 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392589(CHEMBL2153377)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of plasmin assessed as S-2302 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392592(CHEMBL2153381)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of plasmin assessed as S-2302 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392589(CHEMBL2153377)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of tPA assessed as S-2288 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392592(CHEMBL2153381)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of tPA assessed as S-2288 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM7840(RIVAROXABAN | US8822458, 44 | US8822458, 97)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 minsMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392592(CHEMBL2153381)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392595(CHEMBL2153392)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392589(CHEMBL2153377)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392593(CHEMBL2153383)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392596(CHEMBL2153393)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392590(CHEMBL2153378)
Affinity DataIC50:  4nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392588(CHEMBL2153376)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392594(CHEMBL2153391)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392597(CHEMBL2153394)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392591(CHEMBL2153380)
Affinity DataIC50:  9nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392598(CHEMBL2153395)
Affinity DataIC50:  11.6nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50139534(2-[2-Methoxy-6-({3-trifluoromethyl-4-[4-(3-trifluo...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human Plasminogen activator inhibitor 1 using HRP substrate after 30 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50354841(CHEMBL1834496)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human Plasminogen activator inhibitor 1 using HRP substrate after 30 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50354839(CHEMBL1834494)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human Plasminogen activator inhibitor 1 using HRP substrate after 30 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50354834(CHEMBL1834489)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human Plasminogen activator inhibitor 1 using HRP substrate after 30 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242808(2-((3,5-bis(trifluoromethyl)benzyl)(4-(3-(trifluor...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50354835(CHEMBL1834490)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of human Plasminogen activator inhibitor 1 using HRP substrate after 30 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242811(2-((3,5-bis(trifluoromethyl)benzyl)(4-(N-methyl-3,...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242810(2-((3,5-bis(trifluoromethyl)benzyl)(4-(N-(4-(trifl...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242812(2-((3,5-bis(trifluoromethyl)benzyl)(4-(N-propyl-3,...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242805(2-((3,5-bis(trifluoromethyl)benzyl)(4-(N-(4-(trifl...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242790(2-((3,5-bis(trifluoromethyl)benzyl)(4-(4-(trifluor...)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50149275(2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242809(2-((3,5-bis(trifluoromethyl)benzyl)(4-(N-allyl-3-(...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242813(2-((3,5-bis(trifluoromethyl)benzyl)(4-(N-allyl-3,5...)
Affinity DataIC50:  1.28E+4nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242803(2-((3,5-bis(trifluoromethyl)benzyl)(4-(N-allyl-4-(...)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242774(CHEMBL460054 | N-(3,5-Bis-trifluoromethyl-benzyl)-...)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50354840(CHEMBL1834495)
Affinity DataIC50:  1.46E+4nMAssay Description:Inhibition of human Plasminogen activator inhibitor 1 using HRP substrate after 30 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50149275(2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of human Plasminogen activator inhibitor 1 using HRP substrate after 30 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242802(2-((3,5-bis(trifluoromethyl)benzyl)(4-(N-pentyl-4-...)
Affinity DataIC50:  1.49E+4nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242791(2-((3,5-bis(trifluoromethyl)benzyl)(4-(3-(trifluor...)
Affinity DataIC50:  1.54E+4nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242801(2-((3,5-bis(trifluoromethyl)benzyl)(4-(N-propyl-4-...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50354842(CHEMBL1834497)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of human Plasminogen activator inhibitor 1 using HRP substrate after 30 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242773(CHEMBL460053 | N-(4'-Trifluoromethoxy-biphenyl-4-y...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242800(2-((3,5-bis(trifluoromethyl)benzyl)(4-(N-methyl-4-...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50354837(CHEMBL1834492)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of human Plasminogen activator inhibitor 1 using HRP substrate after 30 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242789(2-((3,5-bis(trifluoromethyl)benzyl)(4-(3,4-difluor...)
Affinity DataIC50:  2.99E+4nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242804(2-((3,5-bis(trifluoromethyl)benzyl)(4-(N-benzyl-4-...)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50242807(2-((3,5-bis(trifluoromethyl)benzyl)(4-(N-methyl-4-...)
Affinity DataIC50:  6.10E+4nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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