Compile Data Set for Download or QSAR
maximum 50k data
Found 41 with Last Name = 'pegg' and Initial = 'sj'
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033933((R)-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033920((R)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50:  6nMAssay Description:Ability to inhibit Thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033901((R)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50:  7nMAssay Description:Ability to inhibit Thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033913((R)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50:  9nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033921((R)-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-y...)
Affinity DataIC50:  24nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033902((R)-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-y...)
Affinity DataIC50:  34nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033900((R)-2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6...)
Affinity DataIC50:  40nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033927((R)-2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6...)
Affinity DataIC50:  42nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033930((R)-2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6...)
Affinity DataIC50:  42nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033910(4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50:  44nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033899(CHEMBL264095 | N-(3-Cyano-benzyl)-4-[(2,7-dimethyl...)
Affinity DataIC50:  48nMAssay Description:Ability to inhibit Thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033937((R)-3-Methyl-2-{4-[(2-methyl-4-oxo-3,4-dihydro-qui...)
Affinity DataIC50:  58nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033898((R)-3,3-Dimethyl-2-{4-[(2-methyl-4-oxo-3,4-dihydro...)
Affinity DataIC50:  58nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033928((R)-4-Carbamoyl-2-{4-[(2-methyl-4-oxo-3,4-dihydro-...)
Affinity DataIC50:  67nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033917((R)-(4-Fluoro-phenyl)-{4-[(2-methyl-4-oxo-3,4-dihy...)
Affinity DataIC50:  89nMAssay Description:Ability to inhibit Thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033904(4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50:  100nMAssay Description:Ability to inhibit Thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033906(4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50:  110nMAssay Description:Ability to inhibit Thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033932(4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmeth...)
Affinity DataIC50:  110nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033903(4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50:  114nMAssay Description:Ability to inhibit Thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033918((R)-2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6...)
Affinity DataIC50:  150nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033935((R)-(3-Hydroxy-phenyl)-{4-[(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50:  160nMAssay Description:Ability to inhibit Thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033905((R)-2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6...)
Affinity DataIC50:  170nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033925(3-({4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50:  270nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033908(CHEMBL268100 | N-(3-Cyano-benzyl)-4-[(2-methyl-4-o...)
Affinity DataIC50:  280nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033922(4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmeth...)
Affinity DataIC50:  320nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033934(4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmeth...)
Affinity DataIC50:  450nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033915(4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmeth...)
Affinity DataIC50:  520nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033923(CHEMBL6560 | {4-[(2-Methyl-4-oxo-3,4-dihydro-quina...)
Affinity DataIC50:  520nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033924(CHEMBL6829 | N-Benzyl-4-[(2-methyl-4-oxo-3,4-dihyd...)
Affinity DataIC50:  720nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033931(4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmeth...)
Affinity DataIC50:  760nMAssay Description:Ability to inhibit Thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033919(4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmeth...)
Affinity DataIC50:  770nMAssay Description:Ability to inhibit Thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033926(4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmeth...)
Affinity DataIC50:  860nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033909(CHEMBL6590 | N-Furan-3-ylmethyl-4-[(2-methyl-4-oxo...)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033914(CHEMBL264097 | N-Furan-2-ylmethyl-4-[(2-methyl-4-o...)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033936(4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmeth...)
Affinity DataIC50:  1.46E+3nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033912(4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmeth...)
Affinity DataIC50:  1.72E+3nMAssay Description:Ability to inhibit Thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033911(4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmeth...)
Affinity DataIC50:  1.82E+3nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033907(4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmeth...)
Affinity DataIC50:  2.26E+3nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033916(CHEMBL6498 | N-Methyl-4-[(2-methyl-4-oxo-3,4-dihyd...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033929(CHEMBL268854 | N-(4-Chloro-benzyl)-4-[(2-methyl-4-...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033938(CHEMBL6307 | N-Ethyl-4-[(2-methyl-4-oxo-3,4-dihydr...)
Affinity DataIC50:  2.29E+4nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed