Compile Data Set for Download or QSAR
maximum 50k data
Found 48 with Last Name = 'pendergast' and Initial = 'w'
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040857((S)-2-{2-Fluoro-4-[(3-methyl-1-oxo-1,2-dihydro-ben...)
Affinity DataKi:  0.0900nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase(purified recombinant human gene) from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040861((S)-2-(5-(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUIN...)
Affinity DataKi:  0.0900nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase(purified recombinant human gene) from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040865((S)-2-{4-[(3-Methyl-1-oxo-1,2-dihydro-benzo[f]quin...)
Affinity DataKi:  0.440nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase(purified recombinant human gene) from E. coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040860((S)-2-({5-[(3-Methyl-1-oxo-1,2-dihydro-benzo[f]qui...)
Affinity DataKi:  1.10nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase(purified recombinant human gene) from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040863((S)-2-{4-[(3-Amino-1-oxo-1,2-dihydro-benzo[f]quina...)
Affinity DataKi:  1.20nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase(purified recombinant human gene) from E. coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042378(2-[4-(3-Amino-1-oxo-1,2,5,6-tetrahydro-benzo[f]qui...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040859((S)-2-{5-[Methyl-(3-methyl-1-oxo-1,2-dihydro-benzo...)
Affinity DataKi:  2.5nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase(purified recombinant human gene) from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040862((S)-2-{6-[(3-Methyl-1-oxo-1,2-dihydro-benzo[f]quin...)
Affinity DataKi:  4nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase(purified recombinant human gene) from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040858((S)-2-[4-(3-Methyl-1-oxo-1,2-dihydro-benzo[f]quina...)
Affinity DataKi:  5.5nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase(purified recombinant human gene) from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040858((S)-2-[4-(3-Methyl-1-oxo-1,2-dihydro-benzo[f]quina...)
Affinity DataKi:  5.5nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042375(2-[4-(3-Methyl-1-oxo-1,2,5,6-tetrahydro-benzo[f]qu...)
Affinity DataKi:  18nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50230985(CHEMBL306705)
Affinity DataKi:  20nMAssay Description:Inhibition of purified human thymidylate synthase (TS) isolated from an Escherichia coli harboring a plasmid with thy A gene cloned from SV40 transfo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040864((S)-2-{4-[Methyl-(3-methyl-1-oxo-1,2-dihydro-benzo...)
Affinity DataKi:  22nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase(purified recombinant human gene) from E. coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042382(2-[4-(3-Amino-1-oxo-1,2,5,6-tetrahydro-benzo[f]qui...)
Affinity DataKi:  57nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042380(2-[4-(3-Amino-8-bromo-1-oxo-1,2,5,6-tetrahydro-ben...)
Affinity DataKi:  79nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231342(CHEMBL118750)
Affinity DataKi:  100nMAssay Description:Inhibition of purified human thymidylate synthase (TS) isolated from an Escherichia coli harboring a plasmid with thy A gene cloned from SV40 transfo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042376(2-{[4-(3-Amino-1-oxo-1,2,5,6-tetrahydro-benzo[f]qu...)
Affinity DataKi:  660nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042381(3-Methyl-2H-benzo[f]quinazolin-1-one | CHEMBL41889...)
Affinity DataKi:  5.40E+3nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042383(3-Amino-5,6-dihydro-2H-benzo[f]quinazolin-1-one | ...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042373(2-[4-(3-Methyl-1-oxo-1,2-dihydro-benzo[f]quinazoli...)
Affinity DataKi:  7.37E+3nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042377(3-Amino-8-bromo-5,6-dihydro-2H-benzo[f]quinazolin-...)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231341(CHEMBL116508)
Affinity DataKi:  1.64E+4nMAssay Description:Inhibition of purified human thymidylate synthase (TS) isolated from an Escherichia coli harboring a plasmid with thy A gene cloned from SV40 transfo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042374(2-{Methyl-[4-(3-methyl-1-oxo-1,2,5,6-tetrahydro-be...)
Affinity DataKi:  1.67E+4nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042379(3-Methyl-5,6-dihydro-2H-benzo[f]quinazolin-1-one |...)
Affinity DataKi:  3.56E+4nMAssay Description:Inhibition of purified human thymidylate synthase isolated from an E. coli harboring thy A gene cloned from SV40 transformed human fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044608(3-Amino-8,9-dichloro-5,6-dihydro-2H-benzo[f]quinaz...)
Affinity DataIC50:  2.96E+3nMAssay Description:Tested for inhibition against thymidylate synthase (TS) in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044612(3-Amino-7,9-dimethyl-5,6-dihydro-2H-benzo[f]quinaz...)
Affinity DataIC50:  1.30E+4nMAssay Description:Tested for inhibition against thymidylate synthase (TS) in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044614(2-Amino-11,12-dihydro-3H-1,3-diaza-chrysen-4-one |...)
Affinity DataIC50:  3.60E+4nMAssay Description:Tested for inhibition against thymidylate synthase (TS) in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403873(CHEMBL1207447)
Affinity DataEC50:  100nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403873(CHEMBL1207447)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y6 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403874(CHEMBL2113465)
Affinity DataEC50:  9.80E+3nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 4(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403874(CHEMBL2113465)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 4(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
Affinity DataEC50:  100nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50371609(CHEMBL1162193)
Affinity DataEC50:  2.20E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 4(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403875(CHEMBL2113398)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403875(CHEMBL2113398)
Affinity DataEC50:  8.40E+3nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50371609(CHEMBL1162193)
Affinity DataEC50:  200nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y6 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 4(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50371609(CHEMBL1162193)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403871(URIDINE_DIPHOSPHATE)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403874(CHEMBL2113465)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y6 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y6 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
Affinity DataEC50:  30nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403872(CHEMBL2113401)
Affinity DataEC50:  5.60E+3nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 4(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403872(CHEMBL2113401)
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403875(CHEMBL2113398)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y6 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50421511(CHEMBL227380)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y6 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403871(URIDINE_DIPHOSPHATE)
Affinity DataEC50:  100nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y6 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403872(CHEMBL2113401)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y6 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 4(Homo sapiens (Human))
Inspire Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403873(CHEMBL1207447)
Affinity DataEC50:  400nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed