TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Competitive inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in LPC hydrolysis measured every 30 secs for 90 mins by Lin...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Inhibition of rat ATX by Michaelis-Menten analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of rat ATX by Michaelis-Menten analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 41nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataKi: 63.1nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis His-tagged AchBPMore data for this Ligand-Target Pair
Affinity DataKi: 63.1nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis His-tagged AchBPMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis His-tagged AchBPMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis His-tagged AchBPMore data for this Ligand-Target Pair
Affinity DataKi: 126nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis His-tagged AchBPMore data for this Ligand-Target Pair
Affinity DataKi: 126nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis His-tagged AchBPMore data for this Ligand-Target Pair
Affinity DataKi: 316nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis His-tagged AchBPMore data for this Ligand-Target Pair
Affinity DataKi: 316nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis His-tagged AchBPMore data for this Ligand-Target Pair
Affinity DataKi: 398nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis His-tagged AchBPMore data for this Ligand-Target Pair
Affinity DataKi: 501nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis His-tagged AchBPMore data for this Ligand-Target Pair
Affinity DataKi: 631nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis His-tagged AchBPMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis His-tagged AchBPMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.26E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis His-tagged AchBPMore data for this Ligand-Target Pair
Affinity DataKi: 1.58E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis His-tagged AchBPMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.16E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis His-tagged AchBPMore data for this Ligand-Target Pair
Affinity DataKi: 3.16E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis His-tagged AchBPMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataKi: 1.26E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of ATX (unknown origin) using lysophosphatidyl choline as substrateMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human ATX expressed in HEK293 cells using FS-3 as substrate preincubated for 15 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human ATX expressed in HEK293 cells using FS-3 as substrate after 15 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human ATX using bisP-nitrophenyl phosphate as substrate measured after 30 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human ATX using bisP-nitrophenyl phosphate as substrate measured after 30 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataIC50: 7.30nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells using LPC as substrate measured every 30 sec for 90 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of rat ATX lysoPLD activity using LPC as substrate assessed as reduction in choline release measured after 60 mins by HVA fluorescence bas...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant HA-tagged ATX (unknown origin) using FS-3 as substrate measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human ATX using bisP-nitrophenyl phosphate as substrate measured after 30 minsMore data for this Ligand-Target Pair