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Found 545 with Last Name = 'powers' and Initial = 'jj'
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327601(6-(3-(4-(8-fluoronaphthalen-1-yl)piperazin-1-yl)pr...)
Affinity DataKi:  0.0141nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327602(6-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propoxy)is...)
Affinity DataKi:  0.0152nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327603(6-(3-(4-(7-fluoronaphthalen-1-yl)piperazin-1-yl)pr...)
Affinity DataKi:  0.0447nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327604(6-(3-(4-(chroman-8-yl)piperazin-1-yl)propoxy)isoin...)
Affinity DataKi:  0.0501nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327605(6-(4-(4-(8-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  0.0504nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327606(6-(4-(4-(2,3-dihydro-1H-inden-4-yl)piperazin-1-yl)...)
Affinity DataKi:  0.0575nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327607(5-(3-(4-(7-fluoronaphthalen-1-yl)piperazin-1-yl)pr...)
Affinity DataKi:  0.102nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327608(6-(3-(4-(isochroman-8-yl)piperazin-1-yl)propoxy)is...)
Affinity DataKi:  0.108nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327593(5-fluoro-6-(4-(4-(8-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  0.118nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327609(7-fluoro-6-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi:  0.128nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327588(5-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propoxy)is...)
Affinity DataKi:  0.149nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327582(6-(4-(4-(naphthalen-1-yl)piperazin-1-yl)butoxy)iso...)
Affinity DataKi:  0.151nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327610(6-(3-(4-(6,7-difluoronaphthalen-1-yl)piperazin-1-y...)
Affinity DataKi:  0.179nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327573(5-(4-(4-(naphthalen-1-yl)piperazin-1-yl)butoxy)iso...)
Affinity DataKi:  0.204nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327611(5-(4-(4-(7-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  0.243nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327612(6-(3-(4-(5,6,7,8-tetrahydronaphthalen-1-yl)piperaz...)
Affinity DataKi:  0.269nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327575(6-(4-(4-(isochroman-8-yl)piperazin-1-yl)butoxy)iso...)
Affinity DataKi:  0.279nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327613(6-(3-(4-(2,3-dihydro-1H-inden-4-yl)piperazin-1-yl)...)
Affinity DataKi:  0.302nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327587(7-chloro-6-(3-(4-(8-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  0.312nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327578(5-fluoro-6-(3-(4-(7-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  0.341nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327611(5-(4-(4-(7-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  0.483nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327595(6-(3-(4-(6-fluoronaphthalen-1-yl)piperazin-1-yl)pr...)
Affinity DataKi:  0.517nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327602(6-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propoxy)is...)
Affinity DataKi:  0.541nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327590(7-fluoro-6-(4-(4-(8-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  0.568nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327581(6-(4-(4-(1,3-dihydroisobenzofuran-4-yl)piperazin-1...)
Affinity DataKi:  0.575nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327614(6-(4-(4-(chroman-8-yl)piperazin-1-yl)butoxy)isoind...)
Affinity DataKi:  0.576nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327580(7-methyl-6-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi:  0.615nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327615(5-fluoro-6-(4-(4-(naphthalen-1-yl)piperazin-1-yl)b...)
Affinity DataKi:  0.637nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327598(5-methyl-6-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi:  0.670nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327586(5-fluoro-6-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi:  0.671nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327607(5-(3-(4-(7-fluoronaphthalen-1-yl)piperazin-1-yl)pr...)
Affinity DataKi:  0.720nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327606(6-(4-(4-(2,3-dihydro-1H-inden-4-yl)piperazin-1-yl)...)
Affinity DataKi:  0.740nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327616(7-chloro-6-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi:  0.786nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327591(5-methyl-6-(4-(4-(naphthalen-1-yl)piperazin-1-yl)b...)
Affinity DataKi:  0.803nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327584(6-(4-(4-(6-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  0.812nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327589(5-chloro-6-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi:  0.814nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327617(6-(4-(4-(7-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  0.838nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327585(5-chloro-6-(3-(4-(8-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  0.859nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327614(6-(4-(4-(chroman-8-yl)piperazin-1-yl)butoxy)isoind...)
Affinity DataKi:  0.863nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327615(5-fluoro-6-(4-(4-(naphthalen-1-yl)piperazin-1-yl)b...)
Affinity DataKi:  0.877nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327592(5-fluoro-6-(3-(4-(6-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  0.880nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327618(5-fluoro-6-(4-(4-(6-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  0.891nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327619(7-fluoro-6-(3-(4-(7-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  0.904nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327605(6-(4-(4-(8-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  0.951nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327621(6-(3-(4-(6-fluoronaphthalen-1-yl)piperazin-1-yl)pr...)
Affinity DataKi:  1.08nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327620(7-fluoro-6-(4-(4-(naphthalen-1-yl)piperazin-1-yl)b...)
Affinity DataKi:  1.08nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327622(7-chloro-6-(4-(4-(8-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  1.13nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327623(5-fluoro-6-(3-(4-(8-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  1.19nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327624(7-methyl-6-(4-(4-(naphthalen-1-yl)piperazin-1-yl)b...)
Affinity DataKi:  1.26nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327583(6-(4-(4-(6,7-difluoronaphthalen-1-yl)piperazin-1-y...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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