Found 1191 with Last Name = 'quinn' and Initial = 'kp' 
Affinity DataIC50: 0.130nMAssay Description:Inhibition of gamma-secretase in human IMR32 cell membrane using APP as substrate after 2 hrs by ELISAMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of gamma-secretase in human IMR32 cell membrane using APP as substrate after 2 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of gamma-secretase in human IMR32 cell membrane using APP as substrate after 2 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:Inhibition of gamma-secretase in human IMR32 cell membrane using APP as substrate after 2 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.360nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of gamma-secretase in human IMR32 cell membrane using APP as substrate after 2 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.440nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: <0.5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.570nMAssay Description:Inhibition of gamma-secretase in human IMR32 cell membrane using APP as substrate after 2 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.620nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PI3Kdelta (unknown origin) in presence of [gamma-32P]ATP by phosphorimaging assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.740nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.75nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.930nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant JNK1 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant JNK1 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant JNK1 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of cathepsin-D (unknown origin) using C-terminal biotinylated peptide substrate treated 30 mins before addition of peptide substrate measu...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of gamma-secretase in human IMR32 cell membrane using APP as substrate after 2 hrs by ELISAMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Elan Pharmaceuticals
Curated by ChEMBL
Elan Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of wild type GST-tagged LRRK2 (970 to 2527 amino acid residues) (unknown origin) assessed as inhibition of biotinylated-LRRKtide phosphory...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Elan Pharmaceuticals
Curated by ChEMBL
Elan Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of wild type GST-tagged LRRK2 (970 to 2527 amino acid residues) (unknown origin) assessed as inhibition of biotinylated-LRRKtide phosphory...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Elan Pharmaceuticals
Curated by ChEMBL
Elan Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of wild type GST-tagged LRRK2 (970 to 2527 amino acid residues) (unknown origin) assessed as inhibition of biotinylated-LRRKtide phosphory...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of gamma-secretase in human IMR32 cell membrane using APP as substrate after 2 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
