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Found 76 with Last Name = 'reily' and Initial = 'md'
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369268(CHEMBL1790519)
Affinity DataIC50:  1nMAssay Description:Inhibition of binding to Endothelin A receptor of rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50032181(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  4nMAssay Description:Inhibition of binding to Endothelin A receptor of rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50366421(CHEMBL1791271)
Affinity DataIC50:  14nMAssay Description:Inhibition of [125I]endothelin-1 [ET-1] binding to endothelin A receptor (ETA) of rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50032181(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  15nMAssay Description:Inhibitory concentration was evaluated by measuring the binding affinity at the Endothelin B receptor in rat cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369269(CHEMBL1793932)
Affinity DataIC50:  20nMAssay Description:Inhibition of binding to Endothelin B receptor of rat cerebellar membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369268(CHEMBL1790519)
Affinity DataIC50:  40nMAssay Description:Inhibition of binding to Endothelin B receptor of rat cerebellar membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50366424(CHEMBL2369709)
Affinity DataIC50:  40nMAssay Description:Inhibition of [125I]endothelin-1 [ET-1] binding to endothelin A receptor (ETA) of rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50366424(CHEMBL2369709)
Affinity DataIC50:  40nMAssay Description:Inhibition of [125I]-endothelin-3 [ET-3] binding to endothelin B receptor (ETB) of rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  46nMAssay Description:Inhibition of Acetylcholinesterase in rat red blood cellMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50032172((S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propi...)
Affinity DataIC50:  58nMAssay Description:Inhibition of binding to Endothelin A receptor of rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50366421(CHEMBL1791271)
Affinity DataIC50:  60nMAssay Description:Inhibition of [125I]-endothelin-3 [ET-3] binding to endothelin B receptor (ETB) of rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  75nMAssay Description:Inhibition of Acetylcholinesterase in monkey red blood cellMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  78nMAssay Description:Inhibition of Acetylcholinesterase in human red blood cellMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369267(CHEMBL2369736)
Affinity DataIC50:  80nMAssay Description:Inhibition of binding to Endothelin A receptor of rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369267(CHEMBL2369736)
Affinity DataIC50:  80nMAssay Description:Inhibition of binding to Endothelin B receptor of rat cerebellar membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50032172((S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propi...)
Affinity DataIC50:  130nMAssay Description:Inhibitory concentration was evaluated by measuring the binding affinity at the Endothelin B receptor in rat cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  143nMAssay Description:Inhibition of Acetylcholinesterase in mouse red blood cellMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369273(CHEMBL1793926)
Affinity DataIC50:  200nMAssay Description:Inhibition of binding to Endothelin A receptor of rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369266(CHEMBL1793925)
Affinity DataIC50: >250nMAssay Description:Inhibition of binding to Endothelin B receptor of rat cerebellar membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369264(CHEMBL1793929)
Affinity DataIC50: >250nMAssay Description:Inhibition of binding to Endothelin B receptor of rat cerebellar membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369265(CHEMBL1793928)
Affinity DataIC50: >250nMAssay Description:Inhibition of binding to Endothelin B receptor of rat cerebellar membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369269(CHEMBL1793932)
Affinity DataIC50:  250nMAssay Description:Inhibition of binding to Endothelin A receptor of rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369264(CHEMBL1793929)
Affinity DataIC50:  260nMAssay Description:Inhibition of binding to Endothelin A receptor of rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369266(CHEMBL1793925)
Affinity DataIC50:  260nMAssay Description:Inhibition of binding to Endothelin A receptor of rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM9347((2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahyd...)
Affinity DataIC50:  361nMAssay Description:Inhibition of Acetylcholinesterase in rat red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50052410(9-Amino-1,2,3,4-tetrahydro-acridin-4-ol | CHEMBL31...)
Affinity DataIC50:  411nMAssay Description:Inhibition of Acetylcholinesterase in rat red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50052410(9-Amino-1,2,3,4-tetrahydro-acridin-4-ol | CHEMBL31...)
Affinity DataIC50:  476nMAssay Description:Inhibition of Acetylcholinesterase in monkey red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50052409(7-Hydroxytacrine | 9-Amino-1,2,3,4-tetrahydro-acri...)
Affinity DataIC50:  483nMAssay Description:Inhibition of Acetylcholinesterase in rat red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50052410(9-Amino-1,2,3,4-tetrahydro-acridin-4-ol | CHEMBL31...)
Affinity DataIC50:  521nMAssay Description:Inhibition of Acetylcholinesterase in human red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369273(CHEMBL1793926)
Affinity DataIC50:  600nMAssay Description:Inhibition of binding to Endothelin B receptor of rat cerebellar membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50052409(7-Hydroxytacrine | 9-Amino-1,2,3,4-tetrahydro-acri...)
Affinity DataIC50:  623nMAssay Description:Inhibition of Acetylcholinesterase in human red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369270(CHEMBL1793933)
Affinity DataIC50:  700nMAssay Description:Inhibition of binding to Endothelin A receptor of rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM9347((2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahyd...)
Affinity DataIC50:  702nMAssay Description:Inhibition of Acetylcholinesterase in human red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50052409(7-Hydroxytacrine | 9-Amino-1,2,3,4-tetrahydro-acri...)
Affinity DataIC50:  759nMAssay Description:Inhibition of Acetylcholinesterase in monkey red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369265(CHEMBL1793928)
Affinity DataIC50:  880nMAssay Description:Inhibition of binding to Endothelin A receptor of rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM9347((2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahyd...)
Affinity DataIC50:  954nMAssay Description:Inhibition of Acetylcholinesterase in monkey red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369270(CHEMBL1793933)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of binding to Endothelin B receptor of rat cerebellar membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM9347((2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahyd...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Acetylcholinesterase in mouse red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50052409(7-Hydroxytacrine | 9-Amino-1,2,3,4-tetrahydro-acri...)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of Acetylcholinesterase in mouse red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369263(CHEMBL1793924)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of binding to Endothelin B receptor of rat cerebellar membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50052410(9-Amino-1,2,3,4-tetrahydro-acridin-4-ol | CHEMBL31...)
Affinity DataIC50:  1.43E+3nMAssay Description:Inhibition of Acetylcholinesterase in mouse red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369271(CHEMBL1793934)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of binding to Endothelin B receptor of rat cerebellar membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50052411(9-Amino-1,2,3,4-tetrahydro-acridin-2-ol | CHEMBL31...)
Affinity DataIC50:  1.61E+3nMAssay Description:Inhibition of Acetylcholinesterase in human red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50052411(9-Amino-1,2,3,4-tetrahydro-acridin-2-ol | CHEMBL31...)
Affinity DataIC50:  1.77E+3nMAssay Description:Inhibition of Acetylcholinesterase in rat red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50366423(CHEMBL1791279)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of [125I]endothelin-1 [ET-1] binding to endothelin A receptor (ETA) of rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50366423(CHEMBL1791279)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of [125I]-endothelin-3 [ET-3] binding to endothelin B receptor (ETB) of rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50052411(9-Amino-1,2,3,4-tetrahydro-acridin-2-ol | CHEMBL31...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Acetylcholinesterase in monkey red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369263(CHEMBL1793924)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of binding to Endothelin A receptor of rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50369271(CHEMBL1793934)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of binding to Endothelin A receptor of rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50366416(CHEMBL2369713)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of [125I]-endothelin-3 [ET-3] binding to endothelin B receptor (ETB) of rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails Article
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