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Found 75 with Last Name = 'savvides' and Initial = 'sn'
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208224(2-(3-((1-(2-naphthoyl)piperidin-4-yl)(methyl)carba...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208222((E)-2-(3-chloro-5-fluorostyrylamino)-1-(5-chlorobe...)
Affinity DataKi:  11nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208228(1-(5-chlorobenzo[b]thiophen-3-yl)-2-(naphthalen-2-...)
Affinity DataKi:  36nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
TargetCathepsin G(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208224(2-(3-((1-(2-naphthoyl)piperidin-4-yl)(methyl)carba...)
Affinity DataKi:  38nMAssay Description:Inhibition of human neutrophil Cat GMore data for this Ligand-Target Pair
TargetCathepsin G(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208228(1-(5-chlorobenzo[b]thiophen-3-yl)-2-(naphthalen-2-...)
Affinity DataKi:  9.50E+3nMAssay Description:Inhibition of human neutrophil Cat GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208225((E)-2-(3-chlorostyrylamino)-1-(5-chlorobenzo[b]thi...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208224(2-(3-((1-(2-naphthoyl)piperidin-4-yl)(methyl)carba...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208236(1-(5-chloro-1-methyl-1H-indol-3-yl)-2-(naphthalen-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208243((E)-2-(3,4-difluorostyrylamino)-1-(5-chlorobenzo[b...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208232(1-(5-chloro-1-methyl-1H-indol-3-yl)-2-(naphthalen-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208244((E)-2-(4-fluorostyrylamino)-1-(5-chloro-1-methyl-1...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208222((E)-2-(3-chloro-5-fluorostyrylamino)-1-(5-chlorobe...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208229((E)-2-(3,4-difluorostyrylamino)-1-(5-chloro-1-meth...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208228(1-(5-chlorobenzo[b]thiophen-3-yl)-2-(naphthalen-2-...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208241((E)-1-(5-chlorobenzo[b]thiophen-3-yl)-2-oxo-2-(sty...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208242((E)-2-(3,4-difluorostyrylamino)-1-(5-chlorobenzo[b...)
Affinity DataIC50:  58nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208226((E)-1-(5-chlorobenzo[b]thiophen-3-yl)-2-oxo-2-(sty...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208239((E)-2-(4-fluorostyrylamino)-1-(5-chlorobenzo[b]thi...)
Affinity DataIC50:  66nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208221(1-(5-chlorobenzo[b]thiophen-3-yl)-2-(naphthalen-2-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208227(1-(1-methyl-1H-indol-3-yl)-2-(naphthalen-2-ylamino...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574965(CHEMBL4876372)
Affinity DataIC50:  120nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208234(1-(benzo[b]thiophen-3-yl)-2-(naphthalen-2-ylamino)...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574967(CHEMBL4858644)
Affinity DataIC50:  140nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208223(1-(5-chlorobenzo[b]thiophen-3-yl)-2-(naphthalen-2-...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208235((E)-2-(3,4-difluorostyrylamino)-1-(5-chlorobenzo[b...)
Affinity DataIC50:  165nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208237(1-(naphthalen-1-yl)-2-(naphthalen-2-ylamino)-2-oxo...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208238(CHEMBL223624 | methyl(1-(naphthalen-1-yl)-2-(napht...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574975(CHEMBL4869914)
Affinity DataIC50:  220nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208220(1-(5-chlorobenzo[b]thiophen-3-yl)-2-(naphthalen-2-...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208219((E)-2-(4-methoxystyrylamino)-1-(5-chlorobenzo[b]th...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574970(CHEMBL4860538)
Affinity DataIC50:  450nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574972(CHEMBL4876370)
Affinity DataIC50:  600nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574963(CHEMBL4848605)
Affinity DataIC50:  600nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574964(CHEMBL4868830)
Affinity DataIC50:  650nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574973(CHEMBL4874579)
Affinity DataIC50:  770nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574974(CHEMBL4865732)
Affinity DataIC50:  810nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574956(CHEMBL4854974)
Affinity DataIC50:  890nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208231(1-(1H-indol-3-yl)-2-(naphthalen-2-ylamino)-2-oxoet...)
Affinity DataIC50:  920nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574968(CHEMBL4871611)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574955(CHEMBL4860579)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574961(CHEMBL4854518)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574960(CHEMBL4849731)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208240(1-(5-chlorobenzo[b]thiophen-3-yl)-2-(naphthalen-2-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208233(1-(benzofuran-3-yl)-2-(naphthalen-2-ylamino)-2-oxo...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574943(CHEMBL4870416)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574962(CHEMBL4863370)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574971(CHEMBL4868671)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574966(CHEMBL4855593)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574958(CHEMBL4846640)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50574976(CHEMBL4872239)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv TMPK expressed in Escherichia coli by coupled enzyme based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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