Compile Data Set for Download or QSAR
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Found 1957 with Last Name = 'schwartz' and Initial = 'jc'
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50246381(2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-3,8-di...)
Affinity DataKi:  0.0313nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50492784(CHEMBL2413837)
Affinity DataKi:  0.0450nMAssay Description:Displacement of [125I]iodoproxyfan from histamine H3 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50319536((R)-2-(4-methylpiperidin-1-yl)-6-(2-(2-methylpyrro...)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50492781(CHEMBL2413835)
Affinity DataKi:  0.0570nMAssay Description:Displacement of [125I]iodoproxyfan from histamine H3 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
U. 109

Curated by PDSP Ki Database
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.0600nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50246382(8-chloro-2-(4-(1-cyclobutylpiperidin-4-yloxy)pheny...)
Affinity DataKi:  0.0625nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50278495(4-chloro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pi...)
Affinity DataKi:  0.0680nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50246290(2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-3-meth...)
Affinity DataKi:  0.0688nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50246434(2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-fluo...)
Affinity DataKi:  0.0781nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50110291((7-Chloro-quinolin-4-yl)-[4-(3-piperidin-1-yl-prop...)
Affinity DataKi:  0.0860nMAssay Description:Affinity for displacement of [125I]-iodoproxyfan from human histamine H3 receptors stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50110288(CHEMBL15153 | N-(4-(3-(piperidin-1-yl)propoxy)phen...)
Affinity DataKi:  0.0910nMAssay Description:Affinity for displacement of [125I]-iodoproxyfan from human histamine H3 receptors stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50246334(2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-7-meth...)
Affinity DataKi:  0.0938nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50246435(2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-meth...)
Affinity DataKi:  0.0938nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50246333(2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-6-meth...)
Affinity DataKi:  0.0938nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50278350(4-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pi...)
Affinity DataKi:  0.0940nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50246287(3-benzyl-2-(4-(3-(piperidin-1-yl)propoxy)phenyl)qu...)
Affinity DataKi:  0.0969nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50492783(CHEMBL2413824)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]iodoproxyfan from histamine H3 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50319509((R)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)-2-(pyridi...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50319554((R)-2-(2-methylimidazo[1,2-a]pyridin-3-yl)-6-(2-(2...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHrh3 protein(RAT)
U. 109

Curated by PDSP Ki Database
LigandPNGBDBM22911(2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide |...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50319549((R)-5-methyl-4-(6-(2-(2-methylpyrrolidin-1-yl)ethy...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50319538((R)-1-(4-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)quin...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50319552((R)-6-methyl-5-(6-(2-(2-methylpyrrolidin-1-yl)ethy...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50098203(1-{4-[2-(1H-Imidazol-4-yl)-ethylsulfanyl]-phenyl}-...)
Affinity DataKi:  0.110nMAssay Description:Inhibition of [125I]-iodoproxyfan from rat histamine H3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50319517((R)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)-2-(pyrazi...)
Affinity DataKi:  0.110nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50074629(4-[(1R,2R)-2-(5,5-Dimethyl-hex-1-ynyl)-cyclopropyl...)
Affinity DataKi:  0.120nMAssay Description:In vitro inhibitory activity against Histamine H3 receptor for K+ evoked depolarization-induced release of [3H]-histamine from synaptosomes of rat ce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50492772(CHEMBL2413828)
Affinity DataKi:  0.130nMAssay Description:Displacement of [125I]iodoproxyfan from histamine H3 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50319512((R)-2-(6-methylpyridin-3-yl)-6-(2-(2-methylpyrroli...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHrh3 protein(RAT)
U. 109

Curated by PDSP Ki Database
LigandPNGBDBM22911(2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide |...)
Affinity DataKi:  0.150nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50246243(2-(4-(3-(piperidin-1-yl)propoxy)phenyl)-3-propylqu...)
Affinity DataKi:  0.156nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50246332(2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-5-meth...)
Affinity DataKi:  0.156nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50246380(2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-meth...)
Affinity DataKi:  0.156nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50352357(CHEMBL558655)
Affinity DataKi:  0.158nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50296178((+/-)-(S)-1-{3-[4-(8-Methoxy-3-methyl-4,4-dioxo-3,...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50319547((R)-3-(4-chlorophenyl)-5-methyl-4-(6-(2-(2-methylp...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50319528((R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-6-(2-(2-methy...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50296179((+/-)-1-Cyclobutyl-4-[4-(8-methoxy-3-methyl-4,4-di...)
Affinity DataKi:  0.161nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50352086(CHEMBL1824245)
Affinity DataKi:  0.170nMAssay Description:Displacement of [125I]Iodoproxyfan from recombinant human histamine H3 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50492769(CHEMBL2413836)
Affinity DataKi:  0.170nMAssay Description:Displacement of [125I]iodoproxyfan from histamine H3 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50296176((+/-)-(R)-1-{3-[4-(8-Methoxy-3-methyl-4,4-dioxo-3,...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50319527((R)-2-(3-methyl-1H-pyrazol-4-yl)-6-(2-(2-methylpyr...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50319566((R)-N,N-dimethyl-6-(5-methyl-4-(6-(2-(2-methylpyrr...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50224191((R)-2-(1-(6-ethoxypyridazin-3-yl)-5-methyl-1H-pyra...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50319508((R)-2,4-dimethyl-5-(6-(2-(2-methylpyrrolidin-1-yl)...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHrh3 protein(RAT)
U. 109

Curated by PDSP Ki Database
LigandPNGBDBM22916(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50142788(CHEMBL3759491)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]-spiperone from human dopamine D3 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50278449(4-bromo-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pip...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50319534((R)-2-(2-methoxypyrimidin-5-yl)-6-(2-(2-methylpyrr...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50319533((R)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)-2-(pyrimi...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
U. 109

Curated by PDSP Ki Database
LigandPNGBDBM81798(CAS_39860-99-6 | NSC_62867 | Pipotiazine)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

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