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Found 1077 with Last Name = 'stewart' and Initial = 'el'
TargetEstrogen receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataKi:  0.220nMAssay Description:Ability to displace [3H]-17-beta-estradiol from Estrogen receptor alpha by scintillation proximity assay.More data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataKi:  0.251nMAssay Description:Inhibition of 4 nM progesterone-stimulated transactivation of MMTV-Luc reporter in CV-1 cells expressing PR-BMore data for this Ligand-Target Pair
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086433(CHEMBL3426034)
Affinity DataKi:  0.300nMAssay Description:Inhibition of wild type fully glycosylated human recombinant CD38-catalyzed NAD hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086438(CHEMBL3426039)
Affinity DataKi:  0.450nMAssay Description:Inhibition of wild type fully glycosylated human recombinant CD38-catalyzed NAD hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086434(CHEMBL3426035)
Affinity DataKi:  0.700nMAssay Description:Inhibition of wild type fully glycosylated human recombinant CD38-catalyzed NAD hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataKi:  2.20nMAssay Description:Ability to displace [3H]-17-beta-estradiol from Estrogen receptor alpha by scintillation proximity assay.More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataKi:  3.5nMAssay Description:Ability to displace [3H]-17-beta-estradiol from Estrogen receptor beta by scintillation proximity assay.More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121622(4-[2-(4-(4-Benzyl-piperazin-1-yl)-6-{[3-(4-chloro-...)
Affinity DataKi:  8nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataKi:  10nMAssay Description:Displacement of fluorescent ligand from binding domain of progesterone receptorMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataKi:  10nMAssay Description:Ability to displace [3H]-17-beta-estradiol from Estrogen receptor beta by scintillation proximity assay.More data for this Ligand-Target Pair
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086425(CHEMBL3426030)
Affinity DataKi:  14nMAssay Description:Inhibition of wild type fully glycosylated human recombinant CD38-catalyzed NAD hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121598(4-{2-[4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121626(4-(2-{4-[3-(4-Chloro-phenyl)-propylsulfanyl]-6-pip...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121602(4-[2-(4-{[3-(4-Fluoro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121590(4-{2-[4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121589(4-(2-{4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121608(4-[2-(4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50102194(4-(4-Benzyl-4'-phenyl-3,4,5,6-tetrahydro-2H-[1,2']...)
Affinity DataKi:  20nMAssay Description:Ability to displace [3H]-17-beta-estradiol from Estrogen receptor alpha by scintillation proximity assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121584(4-[2-(4-{[3-(3,4-Difluoro-phenyl)-propyl]-methyl-a...)
Affinity DataKi:  20nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50474916(CHEMBL364712)
Affinity DataKi:  20nMAssay Description:Displacement of fluorescent ligand from binding domain of progesterone receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50474916(CHEMBL364712)
Affinity DataKi:  25nMAssay Description:Inhibition of 4 nM progesterone-stimulated transactivation of MMTV-Luc reporter in CV-1 cells expressing PR-BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121604(4-(2-{4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  25nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121601(4-[2-(4-{[3-(2,4-Dichloro-phenyl)-propyl]-methyl-a...)
Affinity DataKi:  25nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121603(4-(2-{4-[(3-Benzo[1,3]dioxol-5-yl-propyl)-methyl-a...)
Affinity DataKi:  30nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121634(4-[2-(4-(4-Allyl-piperazin-1-yl)-6-{[3-(4-chloro-p...)
Affinity DataKi:  30nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121600(4-{2-[4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  35nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50474917(CHEMBL366252)
Affinity DataKi:  40nMAssay Description:Displacement of fluorescent ligand from binding domain of progesterone receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121587(CHEMBL153395 | cis-4-(2-{4-[Methyl-(2-phenyl-cyclo...)
Affinity DataKi:  40nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121633(4-[2-(4-{[3-(2-Chloro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  40nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50474911(CHEMBL192314)
Affinity DataKi:  40nMAssay Description:Displacement of fluorescent ligand from binding domain of progesterone receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121636(1-(4-{4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  40nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50474914(CHEMBL190198)
Affinity DataKi:  40nMAssay Description:Displacement of fluorescent ligand from binding domain of progesterone receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121625(4-{2-[4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  40nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121593(4-{2-[4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  50nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121588(4-{2-[4-(4-Methyl-piperazin-1-yl)-6-(3-phenyl-prop...)
Affinity DataKi:  50nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121596(4-(2-{4-[3-(4-Chloro-phenyl)-propylamino]-6-pipera...)
Affinity DataKi:  55nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121590(4-{2-[4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  60nMAssay Description:In vitro binding affinity towards human Estrogen receptor alpha using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50102204(2-Methyl-4-[4-phenyl-6-(propyl-pyridin-2-ylmethyl-...)
Affinity DataKi:  70nMAssay Description:Ability to displace [3H]-17-beta-estradiol from Estrogen receptor alpha by scintillation proximity assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121594(4-[2-(4-{Methyl-[3-(4-trifluoromethyl-phenyl)-prop...)
Affinity DataKi:  75nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121620(4-[3-({4-[2-(4-Hydroxy-phenyl)-ethylamino]-6-piper...)
Affinity DataKi:  90nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121607(4-(2-{4-[2-(4-Chloro-phenoxy)-ethylsulfanyl]-6-pip...)
Affinity DataKi:  90nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121632(1-(4-{4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  100nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121624(4-[2-(4-{[3-(4-Chloro-phenyl)-propyl]-ethyl-amino}...)
Affinity DataKi:  100nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121613(4-(2-{4-[Methyl-(3-p-tolyl-propyl)-amino]-6-pipera...)
Affinity DataKi:  100nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50474919(CHEMBL364924)
Affinity DataKi:  100nMAssay Description:Displacement of fluorescent ligand from binding domain of progesterone receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50474912(CHEMBL190264)
Affinity DataKi:  100nMAssay Description:Displacement of fluorescent ligand from binding domain of progesterone receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121614(1-(4-{4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  110nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50102194(4-(4-Benzyl-4'-phenyl-3,4,5,6-tetrahydro-2H-[1,2']...)
Affinity DataKi:  110nMAssay Description:Ability to displace [3H]-17-beta-estradiol from Estrogen receptor beta by scintillation proximity assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121609((4-{4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino}-...)
Affinity DataKi:  110nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50121621(4-{2-[4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  115nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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