Affinity DataKi: 0.00600nMAssay Description:Inhibition of EGFRChecked by AuthorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Inhibition of CaM-KKbetaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of human JNK1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human JNK2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:Inhibition of human recombinant BACE2 using (europium)CEVNLDAEFK(Qsy7) as substrate incubated for 10 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of human myosin light chain kinaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of GSK3-betaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of adhenosine kinaseChecked by AuthorMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Inhibition of Cdk1/cyclin B1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibition of GSK3-betaChecked by AuthorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 52nMAssay Description:Inhibition of human JNK3Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibition of Cdk7/cyclin HChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Inhibition of human recombinant BACE2 using (europium)CEVNLDAEFK(Qsy7) as substrate incubated for 10 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of p160ROCKChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Inhibition of AblChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Binding affinity to ERK2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Inhibition of ERK1Checked by AuthorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 310nMAssay Description:Inhibition of p38alphaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Inhibition of ERK2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Binding affinity to ERK1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 318nMAssay Description:Inhibition of PKCdeltaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 370nMAssay Description:Inhibition of human recombinant BACE2 using (europium)CEVNLDAEFK(Qsy7) as substrate incubated for 10 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
Affinity DataKi: 530nMAssay Description:Inhibition of ERK2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 740nMAssay Description:Inhibition of human recombinant BACE2 using (europium)CEVNLDAEFK(Qsy7) as substrate incubated for 10 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
Affinity DataKi: 770nMAssay Description:Inhibition of human recombinant BACE2 using (europium)CEVNLDAEFK(Qsy7) as substrate incubated for 10 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
Affinity DataKi: 790nMAssay Description:Inhibition of human recombinant BACE2 using (europium)CEVNLDAEFK(Qsy7) as substrate incubated for 10 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Inhibition of human recombinant BACE2 using (europium)CEVNLDAEFK(Qsy7) as substrate incubated for 10 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of AKTChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of FynChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of EphB3Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of PKCalphaChecked by AuthorMore data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 3.80E+3nMAssay Description:Inhibition of myosin light chain kinaseChecked by AuthorMore data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 7.40E+3nMAssay Description:Inhibition of myosin light chain kinaseChecked by AuthorMore data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 1.01E+4nMAssay Description:Binding affinity at MLCKChecked by AuthorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 1.30E+4nMAssay Description:Inhibition of CaM-KKbetaChecked by AuthorMore data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 2.83E+4nMAssay Description:Binding affinity at MLCKChecked by AuthorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 2.97E+4nMAssay Description:Inhibition of CaM-KKbetaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 3.83E+4nMAssay Description:Inhibition of casein kinase 1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 8.00E+4nMAssay Description:Inhibition of casein kinase 1Checked by AuthorMore data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 1.50E+5nMAssay Description:Binding affinity at MLCKChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00600nMAssay Description:Inhibition of wild type EGFRChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0250nMAssay Description:Inhibition of EGFRChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Inhibition of wild type EGFRChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Inhibition of BACE1 in human SH-SY5Y cells assessed as inhibition of sAPPbeta release after 16 hrs by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of BACE1 in human SH-SY5Y cells assessed as inhibition of sAPPbeta release after 16 hrs by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMAssay Description:Inhibition of BACE1 in human SH-SY5Y cells assessed as inhibition of sAPPbeta release after 16 hrs by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Inhibition of BACE1 in human SH-SY5Y cells assessed as inhibition of sAPPbeta release after 16 hrs by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of GSK3-betaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of GSK3-betaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of JAK2Checked by AuthorMore data for this Ligand-Target Pair