Affinity DataKi: 0.0430nM Kon: 0.0000145M-1s-1 Koff: 3.39E+5s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0430nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0680nM Kon: 0.0000759M-1s-1 Koff: 1.12E+6s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0710nM Kon: 0.0000550M-1s-1 Koff: 7.76E+5s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nM Kon: 0.00000617M-1s-1 Koff: 6.46E+4s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nM Kon: 0.0000117M-1s-1 Koff: 1.02E+5s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nM Kon: 0.0000661M-1s-1 Koff: 3.47E+5s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nM Kon: 0.0000708M-1s-1 Koff: 3.09E+5s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nM Kon: 0.0000182M-1s-1 Koff: 4.57E+4s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research
Curated by ChEMBL
Syntex Research
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Binding affinity against HIV Protease enzyme.(by Dixon analysis)More data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nM Kon: 0.00468M-1s-1 Koff: 1.00E+7s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.590nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.870nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 0.870nMAssay Description:Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research
Curated by ChEMBL
Syntex Research
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Binding affinity against HIV protease enzyme.(by Dixon analysis)More data for this Ligand-Target Pair
Affinity DataKi: 0.920nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.970nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nM Kon: 0.00141M-1s-1 Koff: 1.51E+6s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1nM Kon: 0.0000661M-1s-1 Koff: 7.08E+4s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]bremazocine from human delta opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]bremazocine from cloned human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.41nM Kon: 0.000355M-1s-1 Koff: 2.51E+5s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.58nM Kon: 0.0000112M-1s-1 Koff: 7.08E+3s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.58nM Kon: 0.0000178M-1s-1 Koff: 1.18E+4s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]bremazocine from human delta opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.51nM Kon: 0.000813M-1s-1 Koff: 3.02E+5s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.98nM Kon: 0.000537M-1s-1 Koff: 1.29E+5s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research
Curated by ChEMBL
Syntex Research
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Binding affinity against HIV Protease enzyme.(by Dixon analysis)More data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Displacement of [3H]diprenorphine from cloned human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]bremazocine from cloned human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]bremazocine from human delta opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair