Compile Data Set for Download or QSAR
maximum 50k data
Found 283 with Last Name = 'tirado-rives' and Initial = 'j'
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataKi:  3nMAssay Description:Effective concentration required against L100I mutant HIV-1 reverse transcriptase (as per ref 8 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataKi:  17nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptase (as per ref 6 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataKi:  17nMAssay Description:Binding affinity towards L100I mutant HIV-1 reverse transcriptase (as per ref 10 in the article)More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399046(CHEMBL2178862)
Affinity DataKi:  38nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50206083(CHEMBL3927658 | US10968198, Example 43)
Affinity DataKi:  39nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399047(CHEMBL2178856)
Affinity DataKi:  39nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399054(CHEMBL2178851)
Affinity DataKi:  43nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50206084(CHEMBL3899123)
Affinity DataKi:  48nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50206030(CHEMBL3957289 | US10336721, Example 22 | US1096819...)
Affinity DataKi:  74nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50280114(CHEMBL4160035)
Affinity DataKi:  75nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50280113(CHEMBL4170679)
Affinity DataKi:  90nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50206094(CHEMBL3960793)
Affinity DataKi:  144nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50167985(CHEMBL3798384 | US10336721, Example 21 | US1096819...)
Affinity DataKi:  160nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50206085(CHEMBL3924400)
Affinity DataKi:  200nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50206061(CHEMBL3953102 | US10336721, Example 1 | US10968198...)
Affinity DataKi:  230nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50206087(CHEMBL3897449)
Affinity DataKi:  260nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50206090(CHEMBL3915405)
Affinity DataKi:  360nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50280115(CHEMBL4169208)
Affinity DataKi:  363nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399048(CHEMBL2178861)
Affinity DataKi:  370nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399062(CHEMBL2178843)
Affinity DataKi:  370nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50206093(CHEMBL3925522)
Affinity DataKi:  530nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399056(CHEMBL2178849)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399051(CHEMBL2178855)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399059(CHEMBL2178846)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399049(CHEMBL2178858)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399053(CHEMBL2178852)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399060(CHEMBL2178845)
Affinity DataKi:  5.60E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399065(CHEMBL2178837)
Affinity DataKi:  6.90E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399058(CHEMBL2178847)
Affinity DataKi:  6.90E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399057(CHEMBL2178848)
Affinity DataKi:  7.20E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399050(CHEMBL2178857)
Affinity DataKi:  7.70E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399072(CHEMBL2178826)
Affinity DataKi:  8.60E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399055(CHEMBL2178850)
Affinity DataKi:  1.13E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399071(CHEMBL2178828)
Affinity DataKi:  1.55E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399069(CHEMBL2178830)
Affinity DataKi:  1.93E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399074(CHEMBL2178863)
Affinity DataKi:  2.06E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399066(CHEMBL2178833)
Affinity DataKi:  2.29E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399073(CHEMBL2178867)
Affinity DataKi:  2.54E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399070(CHEMBL2178829)
Affinity DataKi:  2.86E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50167988(CHEMBL3798703)
Affinity DataKi:  3.01E+4nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399067(CHEMBL2178832)
Affinity DataKi:  4.34E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399063(CHEMBL2178841)
Affinity DataKi:  5.72E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399064(CHEMBL2178838)
Affinity DataKi:  6.76E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399052(CHEMBL2178853)
Affinity DataKi:  9.33E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM61233(4-[(3,4-diketo-1-naphthyl)amino]benzenesulfonamide...)
Affinity DataKi:  9.90E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50399047(CHEMBL2178856)
Affinity DataKi:  1.01E+5nMAssay Description:Inhibition of human MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399061(CHEMBL2178844)
Affinity DataKi:  1.22E+5nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50399068(CHEMBL2178831)
Affinity DataKi:  1.22E+5nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50399046(CHEMBL2178862)
Affinity DataKi:  2.70E+5nMAssay Description:Inhibition of human MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50490935(CHEMBL2348625 | d4TTP-4PEG-TMC)
Affinity DataIC50:  3nMAssay Description:Competitive inhibition of C-Terminal histidine-tagged wild type heterodimeric HIV-1 reverse transcriptase p66/p51 assessed as inhibition of dTTP inco...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 283 total ) | Next | Last >>
Jump to: