Affinity DataKi: 0.0460nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0585nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0637nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.122nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.127nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.131nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.143nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:In vitro inhibitory activity against human NK1 receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.183nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.198nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.367nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Binding affinity measured by displacement of tritiated radiolabeled substance P from cloned human NK1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKi: 6.20nMAssay Description:Inhibition of hexa-His-tagged JNK2 expressed in baculoviral system using GST-tagged cJun as substrate preincubated for 15 mins prior ATP addition mea...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Binding affinity measured by displacement of tritiated radiolabeled substance P from cloned human NK1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Inhibition of hexa-His-tagged JNK1 expressed in baculoviral system using GST-tagged c-Jun as substrate preincubated for 15 mins prior ATP addition me...More data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 3(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKi: 89nMAssay Description:Inhibition of human Cdc25CMore data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKi: 95nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Inhibition of Mycobacterium tuberculosis ptpBMore data for this Ligand-Target Pair
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKi: 250nMAssay Description:Inhibition of Mycobacterium tuberculosis ptpBMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity measured by displacement of tritiated radiolabeled substance P from cloned human NK1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis ptpAMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Institute For Medical Research And Occupational Health
Curated by ChEMBL
Institute For Medical Research And Occupational Health
Curated by ChEMBL
Affinity DataKi: 3.90E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Institute For Medical Research And Occupational Health
Curated by ChEMBL
Institute For Medical Research And Occupational Health
Curated by ChEMBL
Affinity DataKi: 7.10E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Institute For Medical Research And Occupational Health
Curated by ChEMBL
Institute For Medical Research And Occupational Health
Curated by ChEMBL
Affinity DataKi: 1.20E+6nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Institute For Medical Research And Occupational Health
Curated by ChEMBL
Institute For Medical Research And Occupational Health
Curated by ChEMBL
Affinity DataKi: 1.40E+6nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0220nMAssay Description:Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0260nMAssay Description:Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0260nMAssay Description:Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0270nMAssay Description:Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0270nMAssay Description:Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...More data for this Ligand-Target Pair
TargetUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 0.0280nMAssay Description:Each assay plate contains wells with vehicle controls (1% DMSO) for the measurement of non-inhibited transfer reaction (=100% Ctl) and wells with 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0330nMAssay Description:Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0330nMAssay Description:Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...More data for this Ligand-Target Pair
TargetUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 0.0340nMAssay Description:Each assay plate contains wells with vehicle controls (1% DMSO) for the measurement of non-inhibited transfer reaction (=100% Ctl) and wells with 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0340nMAssay Description:Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...More data for this Ligand-Target Pair
TargetUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 0.0350nMAssay Description:Each assay plate contains wells with vehicle controls (1% DMSO) for the measurement of non-inhibited transfer reaction (=100% Ctl) and wells with 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0380nMAssay Description:Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0380nMAssay Description:Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...More data for this Ligand-Target Pair
TargetUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 0.0400nMAssay Description:Each assay plate contains wells with vehicle controls (1% DMSO) for the measurement of non-inhibited transfer reaction (=100% Ctl) and wells with 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0450nMAssay Description:Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...More data for this Ligand-Target Pair