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Found 1086 with Last Name = 'walters' and Initial = 'j'
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17129(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.00400nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17127(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.00400nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17122(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.00400nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17136(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.00500nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17135(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.00500nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataKi:  0.00500nMAssay Description:Competitive reversible inhibition of human C-terminal His6-tagged CD73 expressed in HEK293 cells using AMP as substrate preincubated with substrate f...More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17134(4-[(2-amino-1H-imidazol-1-yl)methyl]-3-chloro-N-{4...)
Affinity DataKi:  0.00600nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17111(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.00700nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17137(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.00800nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17124(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0100nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17130(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0100nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17128(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0100nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17125(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0100nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17133(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0100nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17131(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0100nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17123(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0100nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17112(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0120nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17118(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0120nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17104(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0190nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17138(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0200nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17107(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0200nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17132(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0220nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17110(3-[({[4-chloro-5-({4-chloro-2-[(5-chloropyridin-2-...)
Affinity DataKi:  0.0220nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17103(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0240nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17120(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0240nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17106(4-{[carbamoyl(methyl)amino]methyl}-3-chloro-N-{4-c...)
Affinity DataKi:  0.0260nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17119(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0260nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17117(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0310nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17126(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0340nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17109(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0360nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17105(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0450nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17108(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0500nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17121(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0590nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetCoagulation factor X(Rattus norvegicus (rat))
Berlex Biosciences

LigandPNGBDBM17135(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.0600nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17284(2-{[2-(5-carbamimidoyl-2-hydroxyphenoxy)-3,5-diflu...)
Affinity DataKi:  0.110nMAssay Description:Inhibitory potency was measured against human coagulation factor XMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17114(4-{[tert-butyl(4,5-dihydro-1,3-oxazol-2-yl)amino]m...)
Affinity DataKi:  0.120nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17116(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.120nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Canis lupus familiaris (Dog))
Berlex Biosciences

LigandPNGBDBM17111(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.150nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17088(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.160nM ΔG°:  -55.3kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17099(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.180nM ΔG°:  -55.1kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17090(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.210nM ΔG°:  -54.7kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17093(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.220nM ΔG°:  -54.6kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17098(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.240nM ΔG°:  -54.4kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM50066635((4-{2-(5-Carbamimidoyl-2-hydroxy-phenoxy)-3,5-difl...)
Affinity DataKi:  0.240nMAssay Description:Inhibitory potency was measured against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17102(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.260nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17115(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.260nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM50066619(({2-(5-Carbamimidoyl-2-hydroxy-phenoxy)-3,5-difluo...)
Affinity DataKi:  0.260nMAssay Description:Inhibitory potency was measured against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Rattus norvegicus (rat))
Berlex Biosciences

LigandPNGBDBM17111(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.290nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17259(3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]...)
Affinity DataKi:  0.300nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM50066634((4-{2-(5-Carbamimidoyl-2-hydroxy-phenoxy)-3,5-difl...)
Affinity DataKi:  0.310nMAssay Description:Inhibitory potency was measured against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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