Affinity DataKi: 0.124nMAssay Description:Compound was tested for TS activity against human Thymidylate synthase by tight binding kineticsMore data for this Ligand-Target Pair
Affinity DataKi: 0.124nMAssay Description:Compound was tested for TS activity against human Thymidylate synthase by tight binding kineticsMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Agouron Pharmaceuticals
Agouron Pharmaceuticals
Affinity DataKi: 0.400nMAssay Description:Protease activity was measured by continuous chromogenic assay. The chromogenic peptide His-Lys-Ala-Arg-Val-Leu-(p-NO2-Phe)-Glu-Ala-Nleu-Ser was use...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Agouron Pharmaceuticals
Agouron Pharmaceuticals
Affinity DataKi: 0.900nM ΔG°: -53.7kJ/molepH: 5.6 T: 2°CAssay Description:Protease activity was measured by continuous chromogenic assay. The chromogenic peptide His-Lys-Ala-Arg-Val-Leu-(p-NO2-Phe)-Glu-Ala-Nleu-Ser was use...More data for this Ligand-Target Pair
Affinity DataKi: 1.31nMAssay Description:Compound was tested for TS activity against human Thymidylate synthase by tight binding kineticsMore data for this Ligand-Target Pair
Affinity DataKi: 1.31nMAssay Description:Compound was tested for TS activity against human Thymidylate synthase by tight binding kineticsMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Agouron Pharmaceuticals
Agouron Pharmaceuticals
Affinity DataKi: 2nMAssay Description:Protease activity was measured by continuous chromogenic assay. The chromogenic peptide His-Lys-Ala-Arg-Val-Leu-(p-NO2-Phe)-Glu-Ala-Nleu-Ser was use...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Agouron Pharmaceuticals
Agouron Pharmaceuticals
Affinity DataKi: 2nMAssay Description:Protease activity was measured by continuous chromogenic assay. The chromogenic peptide His-Lys-Ala-Arg-Val-Leu-(p-NO2-Phe)-Glu-Ala-Nleu-Ser was use...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Agouron Pharmaceuticals
Agouron Pharmaceuticals
Affinity DataKi: 2nM ΔG°: -51.6kJ/molepH: 5.6 T: 2°CAssay Description:Protease activity was measured by continuous chromogenic assay. The chromogenic peptide His-Lys-Ala-Arg-Val-Leu-(p-NO2-Phe)-Glu-Ala-Nleu-Ser was use...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibitory effect against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Agouron Pharmaceuticals
Agouron Pharmaceuticals
Affinity DataKi: 4nMAssay Description:Protease activity was measured by continuous chromogenic assay. The chromogenic peptide His-Lys-Ala-Arg-Val-Leu-(p-NO2-Phe)-Glu-Ala-Nleu-Ser was use...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity against HRV-14 3C protease.More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity against HRV-14 3C protease.More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity against HRV-14 3C protease.More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of Escherichia coli Thymidylate synthase (TS)More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human Thymidylate synthase (TS)More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Agouron Pharmaceuticals
Agouron Pharmaceuticals
Affinity DataKi: 6nMAssay Description:Protease activity was measured by continuous chromogenic assay. The chromogenic peptide His-Lys-Ala-Arg-Val-Leu-(p-NO2-Phe)-Glu-Ala-Nleu-Ser was use...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Agouron Pharmaceuticals
Agouron Pharmaceuticals
Affinity DataKi: 6nMAssay Description:Protease activity was measured by continuous chromogenic assay. The chromogenic peptide His-Lys-Ala-Arg-Val-Leu-(p-NO2-Phe)-Glu-Ala-Nleu-Ser was use...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity against HRV-14 3C protease.More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:In vitro inhibitory activity of the compound towards human Poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair